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The map label for this gene is pgm [H]

Identifier: 161525666

GI number: 161525666

Start: 2711480

End: 2712937

Strand: Reverse

Name: pgm [H]

Synonym: Bmul_2497

Alternate gene names: 161525666

Gene position: 2712937-2711480 (Counterclockwise)

Preceding gene: 161525673

Following gene: 161525665

Centisome position: 78.67

GC content: 67.83

Gene sequence:

>1458_bases
ATGCGCCGGCACCGGCGAGAGGCCGCCAGACTATTTTCCATGCACGCAACCGAGAGAGAATCGATGATCTCCCAATCCAT
CTTCAAGGCATATGACATCCGCGGCGTGGTCGGCAAGACGCTCGACGCCGACACGGCGCGCAGCATCGGCCGCGCGTTCG
GCAGCGAAGTGCGCGCGCAGGGCGGCGACGCGGTCGTCGTCGCGCGCGACGGCCGCCTGTCCGGGCCCGAGCTCGTCGGC
GCGCTCGCCGACGGGCTGCGTGCGGCAGGCGTCGACGTCGTCGACATCGGCATGGTCCCGACGCCGGTCGGCTACTTCGC
GGCGAGCGTGCCGCTCGCGCTGAAGGGCGGCGAGCGCCGCGTCGATTCGTGCATCGTCGTCACCGGCAGCCACAACCCGC
CCGACTACAACGGCTTCAAGATGGTGCTGCGCGGCGCGGCGATCTACGGCGAGCAGATCCAGGCGCTGTATCGCCGCATC
GTCGACGAGCGCTTCGAGAGCGGCAGCGGCACGTACGAAGAGCACGACGTGGCCGACGCGTACATCGACCGCATCGTCGG
CGACGTGAAGCTCGCGCGCCCGCTGAAGCTCGTCGTCGACGCGGGCAACGGCGTTGCCGGTCCGCTTGCGACGCGCCTGT
TCAAGGCGCTCGGCTGCACGCTGGTCGAGCGCTTCACCGACATCGACGGCACGTTCCCGAACCATCACCCCGATCCGGCC
CACCCGGAAAACCTGCAGGACGTGATCCAGGCGCTGAAGGACACGGACGCCGAGCTCGGCTTCGCGTTCGACGGCGACGG
CGACCGTCTCGGCGTCGTCACGAAGGACGGCCAGATCATCTATCCGGATCGCCAGCTGATGCTGTTCGCCGAGGAAGTGC
TGTCGCGCAACCCGGGCGCGCAGATCATCTACGACGTGAAGTGCACGCGCCACCTCGCGCAATGGGTGAAGTCGAAGGGC
GGCGAGCCGCTGATGTGGAAGACGGGCCACTCGCTCGTGAAGGCGAAGCTGCGCGAAACGGGCGCGCCGCTCGCGGGCGA
AATGAGCGGCCACGTGTTCTTCAAGGATCGCTGGTACGGCTTCGACGACGGCCTCTACACGGGCGCGCGCCTGCTCGAGA
TCCTCGCGAAGACGGCCGACCCGAGCGCCGTGCTGAACGCGCTGCCCGATGCGATGAGCACGCCGGAACTGCAGCTGAAG
CTCGAGGAAGGCGAGAACTTCAGCCTGATCGAGAAGCTGCAGAAGGAAGCGAAGTTCGACGGCGCGGACGAAGTCGTGAC
GATCGACGGCCTGCGTGTCGAGTATCCGGACGGCTTCGGGCTCGCGCGTTCGTCGAACACGACGCCGGTCGTCGTGCTGC
GCTTCGAGGCCGAGACGCAGGACGGCCTGAAGCGCATTCAGGACGACTTCCGCCGTGTGCTGACGGCCGCGAAGCCGGAC
GTGAAGCTGCCGTTCTGA

Upstream 100 bases:

>100_bases
AAATGGGCGGTATGCACGTCATCGAAACCCGCGATTATAAGTGGGATCGGGGCCGCTCCAGCCGTCCCGTCCGTTGTTCC
GCGCGGGGCCTGCGTGTAGC

Downstream 100 bases:

>100_bases
CCTGGGCATCGGGCGGCCGCACGGGTCGCCCCAGCCGGTCGCGCTGGCCGGTCACCTTCTCCCCGAAAAGCGGCGTGCGC
GTGACGCGTGCGCCGCTTTT

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MRRHRREAARLFSMHATERESMISQSIFKAYDIRGVVGKTLDADTARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVG
ALADGLRAAGVDVVDIGMVPTPVGYFAASVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRI
VDERFESGSGTYEEHDVADAYIDRIVGDVKLARPLKLVVDAGNGVAGPLATRLFKALGCTLVERFTDIDGTFPNHHPDPA
HPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWVKSKG
GEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSAVLNALPDAMSTPELQLK
LEEGENFSLIEKLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEAETQDGLKRIQDDFRRVLTAAKPD
VKLPF

Sequences:

>Translated_485_residues
MRRHRREAARLFSMHATERESMISQSIFKAYDIRGVVGKTLDADTARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVG
ALADGLRAAGVDVVDIGMVPTPVGYFAASVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRI
VDERFESGSGTYEEHDVADAYIDRIVGDVKLARPLKLVVDAGNGVAGPLATRLFKALGCTLVERFTDIDGTFPNHHPDPA
HPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWVKSKG
GEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSAVLNALPDAMSTPELQLK
LEEGENFSLIEKLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEAETQDGLKRIQDDFRRVLTAAKPD
VKLPF
>Mature_485_residues
MRRHRREAARLFSMHATERESMISQSIFKAYDIRGVVGKTLDADTARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELVG
ALADGLRAAGVDVVDIGMVPTPVGYFAASVPLALKGGERRVDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRI
VDERFESGSGTYEEHDVADAYIDRIVGDVKLARPLKLVVDAGNGVAGPLATRLFKALGCTLVERFTDIDGTFPNHHPDPA
HPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGAQIIYDVKCTRHLAQWVKSKG
GEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILAKTADPSAVLNALPDAMSTPELQLK
LEEGENFSLIEKLQKEAKFDGADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEAETQDGLKRIQDDFRRVLTAAKPD
VKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=451, Percent_Identity=36.8070953436807, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789566, Length=457, Percent_Identity=26.9146608315098, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 52954; Mature: 52954

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRHRREAARLFSMHATERESMISQSIFKAYDIRGVVGKTLDADTARSIGRAFGSEVRAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHCC
GGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDIGMVPTPVGYFAASVPLALKGGERR
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCC
VDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRIVDERFESGSGTYEEHDVADA
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YIDRIVGDVKLARPLKLVVDAGNGVAGPLATRLFKALGCTLVERFTDIDGTFPNHHPDPA
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGA
CCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCC
QIIYDVKCTRHLAQWVKSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYG
CEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
FDDGLYTGARLLEILAKTADPSAVLNALPDAMSTPELQLKLEEGENFSLIEKLQKEAKFD
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
GADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEAETQDGLKRIQDDFRRVLTAAKPD
CCCCEEEECCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
VKLPF
CCCCC
>Mature Secondary Structure
MRRHRREAARLFSMHATERESMISQSIFKAYDIRGVVGKTLDADTARSIGRAFGSEVRAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHCC
GGDAVVVARDGRLSGPELVGALADGLRAAGVDVVDIGMVPTPVGYFAASVPLALKGGERR
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEECCCCCC
VDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQALYRRIVDERFESGSGTYEEHDVADA
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
YIDRIVGDVKLARPLKLVVDAGNGVAGPLATRLFKALGCTLVERFTDIDGTFPNHHPDPA
HHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HPENLQDVIQALKDTDAELGFAFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNPGA
CCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCC
QIIYDVKCTRHLAQWVKSKGGEPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYG
CEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
FDDGLYTGARLLEILAKTADPSAVLNALPDAMSTPELQLKLEEGENFSLIEKLQKEAKFD
CCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCC
GADEVVTIDGLRVEYPDGFGLARSSNTTPVVVLRFEAETQDGLKRIQDDFRRVLTAAKPD
CCCCEEEECCEEEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
VKLPF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]