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The map label for this gene is cbl [H]

Identifier: 161524805

GI number: 161524805

Start: 1808940

End: 1809866

Strand: Reverse

Name: cbl [H]

Synonym: Bmul_1632

Alternate gene names: 161524805

Gene position: 1809866-1808940 (Counterclockwise)

Preceding gene: 161524806

Following gene: 161524804

Centisome position: 52.48

GC content: 65.91

Gene sequence:

>927_bases
ATGAACTTCCAGCAACTGCGCTTCGTGCGCGAGGCGGTGCGCCAGAACATGAACCTGACCGAGGTCGCGAACGTGCTGTA
CACGTCGCAGTCGGGCGTGTCGAAGCAGATCAAGGACCTCGAGGACGAACTCGGCGTCGACATCTTCATTCGCCGCGGCA
AGCGGCTGACGGGCCTGACCGAGCCCGGCAAGGCCGTGCATCAGCTGATCGAGCGGATGCTGCTCGACGCGGAGAACCTG
CGGCGCGTCGCACGGCAGTTCGCCGATCAGGACAGCGGCCACCTCGTCGTCGCGACGACGCACACGCAGGCGCGCTACGC
GCTGCCGAAGGTGATCCGGCAGTTCACCGACGTGTTCCCGAAGGTCCATCTCGCGCTGCGGCAGGGCAGCCCGCAGCAGA
TCGCGCAGATGATCCTGAACGGCGAGGCCGATCTCGGCATCTCGACCGAGGCGCTCGACCGCTATCCCGACATCGTCACG
TTCCCGTGCTATTCGTGGCACCACACGGTCGTCGTGCCGAAGGGGCATCCGCTCGTCGGCCGTGAAAACCTGACGCTCGA
CGAAATCGCCGAGTATCCGATCATCACGTACGACCAGGACTTCACCGGCCGCTCGCACATCGACCAGGCGTTCGCACAGG
CCGGCGCCGTGCCAGACGTCGTGCTGACCGCGATCGACGCCGACGTGATCAAGACCTACGTCGAACTCGGCATGGGCATC
GGCGTGGTAGCGGCGATGGCCTACGATCCGCAGCGCGACACGGGCCTCGTCGCGCTCGACACGCAGCATCTGTTCGAGGC
GAGCACGACGCGCGTCGGGCTGCGCAAGGGCGCGTTCCTGCGTGCGTATGCGTATCGACTGATCGAGATGTTCGCGCCGC
ACCTGAACGAAGCCGAAATCGCCGGCCAGCTGCGCGAAGCGGTGTGA

Upstream 100 bases:

>100_bases
CGGTACGCGTATTTCCGGCGCGCTGACGCCGGCCAGGCAGGAAGGAGCGCACGGCGCTCCGTATCGACCATCGAACAACG
ACAGCCCAAGAGGCATACCC

Downstream 100 bases:

>100_bases
TCGGCGCAGGCGGGCGCGCGCCTGCTTCGCGCGCGTCCCGTTAGCCGTCGGCGCGCTCCGAATAAACCCTTAAATATTGA
TTAGACGGGTTGCGCGCCGA

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRENLTLDEIAEYPIITYDQDFTGRSHIDQAFAQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGQLREAV

Sequences:

>Translated_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRENLTLDEIAEYPIITYDQDFTGRSHIDQAFAQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGQLREAV
>Mature_308_residues
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLTEPGKAVHQLIERMLLDAENL
RRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFPKVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVT
FPCYSWHHTVVVPKGHPLVGRENLTLDEIAEYPIITYDQDFTGRSHIDQAFAQAGAVPDVVLTAIDADVIKTYVELGMGI
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEIAGQLREAV

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=307, Percent_Identity=54.071661237785, Blast_Score=350, Evalue=9e-98,
Organism=Escherichia coli, GI1787530, Length=296, Percent_Identity=49.6621621621622, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI157672245, Length=225, Percent_Identity=30.2222222222222, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788887, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=25.2559726962457, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788481, Length=258, Percent_Identity=25.1937984496124, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.0663900414938, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789204, Length=246, Percent_Identity=24.7967479674797, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787806, Length=243, Percent_Identity=22.6337448559671, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082132, Length=122, Percent_Identity=34.4262295081967, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=189, Percent_Identity=26.984126984127, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=224, Percent_Identity=26.3392857142857, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=23.4375, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI145693105, Length=237, Percent_Identity=22.3628691983122, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34394; Mature: 34394

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHTVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCCC
RENLTLDEIAEYPIITYDQDFTGRSHIDQAFAQAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEI
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AGQLREAV
HHHHHHCC
>Mature Secondary Structure
MNFQQLRFVREAVRQNMNLTEVANVLYTSQSGVSKQIKDLEDELGVDIFIRRGKRLTGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCC
EPGKAVHQLIERMLLDAENLRRVARQFADQDSGHLVVATTHTQARYALPKVIRQFTDVFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
KVHLALRQGSPQQIAQMILNGEADLGISTEALDRYPDIVTFPCYSWHHTVVVPKGHPLVG
HHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCCC
RENLTLDEIAEYPIITYDQDFTGRSHIDQAFAQAGAVPDVVLTAIDADVIKTYVELGMGI
CCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
GVVAAMAYDPQRDTGLVALDTQHLFEASTTRVGLRKGAFLRAYAYRLIEMFAPHLNEAEI
HHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHH
AGQLREAV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]