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The map label for this gene is frr [H]

Identifier: 161524433

GI number: 161524433

Start: 1389421

End: 1389981

Strand: Direct

Name: frr [H]

Synonym: Bmul_1260

Alternate gene names: 161524433

Gene position: 1389421-1389981 (Clockwise)

Preceding gene: 161524432

Following gene: 161524434

Centisome position: 40.29

GC content: 63.28

Gene sequence:

>561_bases
ATGAGTGTCGCTGATATCAAGAAGGGCGTCGAGCAGAAGATGCAGCGCTCGATCGAAGCGTTCAAGAACGATCTGGCGAA
GATCCGCACGGGCCGCGCGCACACCGGTCTGCTCGATCACGTGCAGGTCGACTACTACGGATCGATGGTGCCGATTTCGC
AGGTCGCGAACCTGACGCTCGTCGATGCGCGCACGATCGGCGTGCAGCCGTGGGAAAAGAACATGGTCGCGAAGGTCGAG
AAGGCGATCCGCGAAGCCGATCTGGGCCTGAACCCGGCGACGGCCGGCGACCTGATCCGCGTGCCGATGCCGCCGCTGAC
GGAAGAGCGCCGCCGCGAGCTGACCAAGGTCGTGAAGGGCGAAGGCGAGACCGCGAAGGTCGCGATCCGCAACCTGCGCC
GCGACGCGAACGAAGCGCTGAAGAAGCTCGTGAAGGACAAGGAAATCTCGGAAGACGACGAGCGCCGTGCCGGCGACGAC
GTGCAGAAGCTCACCGACAAGCACGTCGCCGAAATCGACAAGCTCGTGCAGACCAAGGAAGCCGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
CCGCGGATGCGGGCAAGCGGCGTGGGCAACCGGCTGCGGCGCGCGCTGCGCGCGCCGGGCGGCCCGCGTTCTTTGAAGGT
TTGAAGGTTCGGAGGTTGAA

Downstream 100 bases:

>100_bases
CGACCGTCGTCGCGCGCCGCCTCCTTCCCGCATCCCTGTCTCAACGGCCATGACCTATACCAGCTCTACCGTTCGCGTGC
CTGACGTCGGCGTCGTGCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVE
KAIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKGEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDD
VQKLTDKHVAEIDKLVQTKEAEIMTV

Sequences:

>Translated_186_residues
MSVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVE
KAIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKGEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDD
VQKLTDKHVAEIDKLVQTKEAEIMTV
>Mature_185_residues
SVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVEK
AIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKGEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDDV
QKLTDKHVAEIDKLVQTKEAEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=32.2033898305085, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI291042689, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=54.9450549450549, Blast_Score=213, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24661488, Length=182, Percent_Identity=29.1208791208791, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20807; Mature: 20676

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKNMVAKVEKAIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKG
EEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDDVQKLTDKHVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
AEIMTV
CHHCCC
>Mature Secondary Structure 
SVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKNMVAKVEKAIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKG
EEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDDVQKLTDKHVAEIDKLVQTKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
AEIMTV
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA