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The map label for this gene is alr [H]

Identifier: 161524411

GI number: 161524411

Start: 1360241

End: 1361311

Strand: Direct

Name: alr [H]

Synonym: Bmul_1238

Alternate gene names: 161524411

Gene position: 1360241-1361311 (Clockwise)

Preceding gene: 161524408

Following gene: 161524412

Centisome position: 39.44

GC content: 68.72

Gene sequence:

>1071_bases
ATGCCGCGCCCGATCTCCGCCACCATCCACACCGCCGCTCTCGCGAACAATCTCTCCGTCGTCCGCCGCTATGCCGGCCC
GTCCAAAGTCTGGGCGGTCGTCAAGGCCAATGCGTACGGCCACGGGCTCGCGCGCGTGTTCCCGGGCCTGCGCGGCACCG
ACGGCTTCGGGCTGCTCGATCTCGACGAAGCCGTGAAGCTGCGCGAGCTCGGCTGGGCGGGCCCGATCCTGCTGCTCGAA
GGCTTCTTCCGCTCGACCGACATCGACGTGATCGATCGCTATAGCCTGACGACCACCGTGCACAACGACGAGCAGATGCG
GATGCTGGAAACCGCGCGGCTGTCGAAGCCCGTCAACGTGCAGTTGAAGATGAACAGCGGCATGAACCGGCTCGGCTACG
CGCCGGAGAAATACCGCGCCGCATGGGAGCGCGCCCGCGCGTGTCCGAGCATCGGGCAGATCACGTTAATGACCCATTTT
TCGGATGCCGACAACGAGCGCGGCGTCGCCGAGCAGCTCGCGACTTTCGAGCGCGGCGCGGCGAACATCGCCGGTGCGCG
CTGCCTCGCGAATTCGGCGGCCGTGCTGTGGCATCCGGATACGCATTTCGACTGGGTGCGGCCCGGGATCGTGCTGTACG
GCGCGTCGCCGTCGGGGCTGTCGTCCGATATCGCGGACACCGGGCTGAAGCCGGCGATGACGCTGTCGTCCGAGCTGATC
GCGGTGCAGTCGATCGGCAAGGGGCAGGCGATCGGCTACGGCTCGACGTTCTCCGCGCCGGCGCCGATGCGGATCGGCGT
CGTCGCATGCGGGTACGCGGACGGCTATCCGCGCGTCGCGCCCGAAGGCACGCCGGTGATCGTCGACGGCATCCGCACGC
GCATTGTCGGGCGCGTCTCGATGGACATGATCACGGTCGACCTGACCCCGTGTCCGCAGGCCGGCGTCGGCGCGCGCGTC
GAGCTGTGGGGCAATGCGCTGTCGATCGACGACGTCGCGCGCCATTGCGGGACGATCGGCTACGAGCTCATGTGCGCGGT
CGCGGCCCGCGTGCCGGTGCGGGCGGAATAA

Upstream 100 bases:

>100_bases
GGACTAGCAAGATTCCCCGATCGTTCCGCAAATTGTCGGCTTCGGTGCTCAAAAGGCGCGGTAAGCTGATGATTCGCAAG
CGTCTTTACGTAAATTTCCC

Downstream 100 bases:

>100_bases
GGGCGCGCGCGTGGCAAAACAGAAAACCGTCTATGTCTGCAGCGAGTGCGGCGGACAAACCCCGAAGTGGCAGGGGCAGT
GCCCGTCGTGCCAGGCCTGG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MPRPISATIHTAALANNLSVVRRYAGPSKVWAVVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTTVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYAPEKYRAAWERARACPSIGQITLMTHF
SDADNERGVAEQLATFERGAANIAGARCLANSAAVLWHPDTHFDWVRPGIVLYGASPSGLSSDIADTGLKPAMTLSSELI
AVQSIGKGQAIGYGSTFSAPAPMRIGVVACGYADGYPRVAPEGTPVIVDGIRTRIVGRVSMDMITVDLTPCPQAGVGARV
ELWGNALSIDDVARHCGTIGYELMCAVAARVPVRAE

Sequences:

>Translated_356_residues
MPRPISATIHTAALANNLSVVRRYAGPSKVWAVVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLE
GFFRSTDIDVIDRYSLTTTVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYAPEKYRAAWERARACPSIGQITLMTHF
SDADNERGVAEQLATFERGAANIAGARCLANSAAVLWHPDTHFDWVRPGIVLYGASPSGLSSDIADTGLKPAMTLSSELI
AVQSIGKGQAIGYGSTFSAPAPMRIGVVACGYADGYPRVAPEGTPVIVDGIRTRIVGRVSMDMITVDLTPCPQAGVGARV
ELWGNALSIDDVARHCGTIGYELMCAVAARVPVRAE
>Mature_355_residues
PRPISATIHTAALANNLSVVRRYAGPSKVWAVVKANAYGHGLARVFPGLRGTDGFGLLDLDEAVKLRELGWAGPILLLEG
FFRSTDIDVIDRYSLTTTVHNDEQMRMLETARLSKPVNVQLKMNSGMNRLGYAPEKYRAAWERARACPSIGQITLMTHFS
DADNERGVAEQLATFERGAANIAGARCLANSAAVLWHPDTHFDWVRPGIVLYGASPSGLSSDIADTGLKPAMTLSSELIA
VQSIGKGQAIGYGSTFSAPAPMRIGVVACGYADGYPRVAPEGTPVIVDGIRTRIVGRVSMDMITVDLTPCPQAGVGARVE
LWGNALSIDDVARHCGTIGYELMCAVAARVPVRAE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=56.9405099150142, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=44.6022727272727, Blast_Score=291, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38105; Mature: 37974

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPISATIHTAALANNLSVVRRYAGPSKVWAVVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTTVHNDEQMRMLETARLSKPVNV
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECEEEEEEECCCHHHHHHHHHHCCCCCEE
QLKMNSGMNRLGYAPEKYRAAWERARACPSIGQITLMTHFSDADNERGVAEQLATFERGA
EEEECCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCC
ANIAGARCLANSAAVLWHPDTHFDWVRPGIVLYGASPSGLSSDIADTGLKPAMTLSSELI
CHHHHHHHHCCCCEEEECCCCCCCEECCCEEEECCCCCCCCCHHHHCCCCCHHHHHHHHH
AVQSIGKGQAIGYGSTFSAPAPMRIGVVACGYADGYPRVAPEGTPVIVDGIRTRIVGRVS
EEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECCHHHHHEEEEE
MDMITVDLTPCPQAGVGARVELWGNALSIDDVARHCGTIGYELMCAVAARVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRPISATIHTAALANNLSVVRRYAGPSKVWAVVKANAYGHGLARVFPGLRGTDGFGLLD
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCEEE
LDEAVKLRELGWAGPILLLEGFFRSTDIDVIDRYSLTTTVHNDEQMRMLETARLSKPVNV
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECEEEEEEECCCHHHHHHHHHHCCCCCEE
QLKMNSGMNRLGYAPEKYRAAWERARACPSIGQITLMTHFSDADNERGVAEQLATFERGA
EEEECCCCHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCC
ANIAGARCLANSAAVLWHPDTHFDWVRPGIVLYGASPSGLSSDIADTGLKPAMTLSSELI
CHHHHHHHHCCCCEEEECCCCCCCEECCCEEEECCCCCCCCCHHHHCCCCCHHHHHHHHH
AVQSIGKGQAIGYGSTFSAPAPMRIGVVACGYADGYPRVAPEGTPVIVDGIRTRIVGRVS
EEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECCHHHHHEEEEE
MDMITVDLTPCPQAGVGARVELWGNALSIDDVARHCGTIGYELMCAVAARVPVRAE
EEEEEEECCCCCCCCCCCEEEECCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA