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The map label for this gene is yhhU [C]

Identifier: 161524272

GI number: 161524272

Start: 1199131

End: 1199886

Strand: Direct

Name: yhhU [C]

Synonym: Bmul_1096

Alternate gene names: 161524272

Gene position: 1199131-1199886 (Clockwise)

Preceding gene: 161524271

Following gene: 161524273

Centisome position: 34.77

GC content: 75.4

Gene sequence:

>756_bases
ATGTCCATGCCGCCCGATTCCGTTTCCCCGGCCGATTCGCCGTCCGCCTACCGCATGCACGCGCTCGACGTGCCGCATGC
GGCCGCGCGGGCCGGCGTGCAGGTCGTGCGCGTCGATTTCGACTGGGACGTGCCGCTCACCGCGCGCGCATATGCGGCGC
TGAGCGAGGCGGAGCGCGCGCGGGCCGCGCGCTATCTACGGCACGCGGATGCCGTGCGCAGCGCCGCGACGCGGGCCGCG
CTGCGCGACGTGCTCGGCGCGGCGCTGCAGGTTGCACCGCACGCGATCGCGATCGTCGTCGACGAGGCGGGGCGCCCATC
GCTCGATCGGGCGCATCGCGTGCCGCTCGATTTCAACGTGTCGCATGCGGGCGAGCACGCGCTGATCGCGTGGGCGCCGG
CGGGCCGCGTCGGCATCGACATCGAGTGCTGCCACCGTCCGACGGACTGGCGCGCACTCGCCGGCGAAGTCTGCGCGCCG
GCCGAGATCGCGTATCTCGACAGCCTGCCGGACGATGCGCGTGCGTCCGCGTTCATGCGCGTGTGGTCGGCGAAGGAGGC
GCTGCTGAAGGCGCTGGGCACCGGCATCGTCGGCGGCCTGGGCGCGTTCGCGGTCGTGCCGCCGCGCGACGCGGCGACGC
CCGCCACGACGATCGTCGATCCGACTGCGCCGGCGGCCGGCGTGGCCGCGTTCGACGCCGCGTGGCTCGACGCGGCGCCC
GGCTACGCGGCGTGCGTCGCGTGGGCGCGCGCGTGA

Upstream 100 bases:

>100_bases
CGTGCGCGTATGGCCGACGCCGCGCGCCGATCGCCGCCGCCGCCGCGGTCGGCCGATCGATTACCATCGGACGTTTTGTT
CCACCGCCCGTCGCCCGCCG

Downstream 100 bases:

>100_bases
GCGGCGCCGGCGCTCATTCGAGCGCCAGGTCGTTCGGCGACGCGTAGCGCGCCTTGATCACGTCGCTCATCGGGAAGTCG
AACGACAGCCCCTTCGGCGG

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSMPPDSVSPADSPSAYRMHALDVPHAAARAGVQVVRVDFDWDVPLTARAYAALSEAERARAARYLRHADAVRSAATRAA
LRDVLGAALQVAPHAIAIVVDEAGRPSLDRAHRVPLDFNVSHAGEHALIAWAPAGRVGIDIECCHRPTDWRALAGEVCAP
AEIAYLDSLPDDARASAFMRVWSAKEALLKALGTGIVGGLGAFAVVPPRDAATPATTIVDPTAPAAGVAAFDAAWLDAAP
GYAACVAWARA

Sequences:

>Translated_251_residues
MSMPPDSVSPADSPSAYRMHALDVPHAAARAGVQVVRVDFDWDVPLTARAYAALSEAERARAARYLRHADAVRSAATRAA
LRDVLGAALQVAPHAIAIVVDEAGRPSLDRAHRVPLDFNVSHAGEHALIAWAPAGRVGIDIECCHRPTDWRALAGEVCAP
AEIAYLDSLPDDARASAFMRVWSAKEALLKALGTGIVGGLGAFAVVPPRDAATPATTIVDPTAPAAGVAAFDAAWLDAAP
GYAACVAWARA
>Mature_250_residues
SMPPDSVSPADSPSAYRMHALDVPHAAARAGVQVVRVDFDWDVPLTARAYAALSEAERARAARYLRHADAVRSAATRAAL
RDVLGAALQVAPHAIAIVVDEAGRPSLDRAHRVPLDFNVSHAGEHALIAWAPAGRVGIDIECCHRPTDWRALAGEVCAPA
EIAYLDSLPDDARASAFMRVWSAKEALLKALGTGIVGGLGAFAVVPPRDAATPATTIVDPTAPAAGVAAFDAAWLDAAPG
YAACVAWARA

Specific function: Probably transfers the 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of a carrier protein domain [H]

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Escherichia coli, GI1789886, Length=96, Percent_Identity=36.4583333333333, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 26161; Mature: 26030

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPPDSVSPADSPSAYRMHALDVPHAAARAGVQVVRVDFDWDVPLTARAYAALSEAERA
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
RAARYLRHADAVRSAATRAALRDVLGAALQVAPHAIAIVVDEAGRPSLDRAHRVPLDFNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCCCC
SHAGEHALIAWAPAGRVGIDIECCHRPTDWRALAGEVCAPAEIAYLDSLPDDARASAFMR
CCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHH
VWSAKEALLKALGTGIVGGLGAFAVVPPRDAATPATTIVDPTAPAAGVAAFDAAWLDAAP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCC
GYAACVAWARA
CHHHHHHHHCC
>Mature Secondary Structure 
SMPPDSVSPADSPSAYRMHALDVPHAAARAGVQVVRVDFDWDVPLTARAYAALSEAERA
CCCCCCCCCCCCCCCEEEEECCCCHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
RAARYLRHADAVRSAATRAALRDVLGAALQVAPHAIAIVVDEAGRPSLDRAHRVPLDFNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCCCCC
SHAGEHALIAWAPAGRVGIDIECCHRPTDWRALAGEVCAPAEIAYLDSLPDDARASAFMR
CCCCCEEEEEECCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHH
VWSAKEALLKALGTGIVGGLGAFAVVPPRDAATPATTIVDPTAPAAGVAAFDAAWLDAAP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCC
GYAACVAWARA
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]