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The map label for this gene is ttuB [H]

Identifier: 161524267

GI number: 161524267

Start: 1192210

End: 1193577

Strand: Reverse

Name: ttuB [H]

Synonym: Bmul_1091

Alternate gene names: 161524267

Gene position: 1193577-1192210 (Counterclockwise)

Preceding gene: 161524269

Following gene: 161524266

Centisome position: 34.61

GC content: 67.84

Gene sequence:

>1368_bases
TTGACCTCGCCCGCCCCTGCCCTGCCCGAGCGCGACCCGCTCGCGTCCGCCGTGTCGAAAGTGAAGTGGCACGTGCTGCC
GCTCGTGCTCGTCATGTTCATCGCGAACTACATCGACCGCGTCAACGTCGGGTTCGTCGACCGCCATCTCGAAGCGTCGA
TCGGCATCGGCGCGGCCGCCTACGGGCTCGGCGCCGGTCTGTTCTTCGTCGGCTACGCGCTGTTCGAAGTGCCGTCGAAC
CTGCTGATGCAGCGCTACGGCGCGCGTGTCTGGCTCGCGCGCATCATGGCCACGTGGGGCATCGTCGCGGCCGCGATGGC
GTTCGTCTGGAACGACACGTCGTTCTACGTGCTGCGCTTCCTGCTCGGCGCCGCCGAAGCGGGCTTCTTCCCCGGCGTCG
TCCTCTATCTGTCGCAATGGCTGCCGCCGCGCGAGCGCGGCAAGGCGATGGCGATCTTCCTCGGCGGCTCGGCGTTCGCG
TCGGTGCTGTCCGGCCCCGTGACGGGCGCGCTGCTGTCGATCCGCGGCCTCGGCCTCGAAGGATGGCAGTGGATGTTCAT
CATCGAAGGCCTGTTCTCGATCGCGCTCTGCGGTAGGAGCTGGGTGCTGCTGAAGTCGCATATCCGCGATGCGACGTGGC
TCGACGCCCAGGAGCGCGCGGCGCTCGAGCAGGCGCTCGACGAAGAACGCGCGCGCCGCGACGTGCGTGCGAACGGGCAC
GTGCCCGCGCTCGCGCTGCTGCGCGATCCGCAGATCGTATTGTTCTGCTTCCTGTACTTCTCGATCCAGCTGACGATCTA
CGCGGCCACGTTCTGGCTGCCGACGATCATCCGCAAGATGGGCGGCCTCAGCGACTTCCAGGTCGGCCTGTACAACACGA
TTCCGTGGATGATCGCGATCGGCGCGATGTACGGCTTCGCGGTGCTGTCCGCGAAGTGGCGGCATCCGCAGCGCTGGCTC
GCCTGCGCACTCGTGCTCGCCGCCTGCGGACTGTTCGCGTCGACGTCGCCCGATCCGGTGTGGTCGTTTGCGTCGATCTG
TTTCGCGGCGCTCGGCTTCAAGGCCGCGTCGTCGCTGTTCTGGCCGATCCCGCAAGGCTACCTCGACACGCGCGTCGCCG
CGGCCGTGATCGCGCTGATCAACTCGATCGGCAATCTCGGCGGCTTCGTCGCGCCGACGGCGTTCGGCTATTTGAAGCAA
CATACGGGTTCGATCACCGGCGGGCTGTATGCGCTCGCGATCGCCTCGCTCGTCGCCGCGTTCGCCGCACTGTTCGCGCG
CACGCACCGGCGCAGCGATCCGCCGCGCGGCCTGCCCGCCGCCGATACCGTAACCAACGCTTCGATGCTCCGCCATGCCG
AACACTGA

Upstream 100 bases:

>100_bases
CCGCGTACCATGTCATACGACGACATACTACGTAAATCGCCATCTGCGCACGCAGCACCAGCCGCCCGTGCGCCGTCGGC
CGCCCCCCCGGAGACACGCC

Downstream 100 bases:

>100_bases
CCTTCCGACCGTCGTCGTGTCGAACGCCCTCGACGGTGACCTAGCCACCTTCTCGCTCGCGCACGACGGCACGCTCGCGC
CGCTCGCGCGCTATCCGGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTSPAPALPERDPLASAVSKVKWHVLPLVLVMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYVLRFLLGAAEAGFFPGVVLYLSQWLPPRERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGLGLEGWQWMFIIEGLFSIALCGRSWVLLKSHIRDATWLDAQERAALEQALDEERARRDVRANGH
VPALALLRDPQIVLFCFLYFSIQLTIYAATFWLPTIIRKMGGLSDFQVGLYNTIPWMIAIGAMYGFAVLSAKWRHPQRWL
ACALVLAACGLFASTSPDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSIGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAFAALFARTHRRSDPPRGLPAADTVTNASMLRHAEH

Sequences:

>Translated_455_residues
MTSPAPALPERDPLASAVSKVKWHVLPLVLVMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYVLRFLLGAAEAGFFPGVVLYLSQWLPPRERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGLGLEGWQWMFIIEGLFSIALCGRSWVLLKSHIRDATWLDAQERAALEQALDEERARRDVRANGH
VPALALLRDPQIVLFCFLYFSIQLTIYAATFWLPTIIRKMGGLSDFQVGLYNTIPWMIAIGAMYGFAVLSAKWRHPQRWL
ACALVLAACGLFASTSPDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSIGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAFAALFARTHRRSDPPRGLPAADTVTNASMLRHAEH
>Mature_454_residues
TSPAPALPERDPLASAVSKVKWHVLPLVLVMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSNL
LMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYVLRFLLGAAEAGFFPGVVLYLSQWLPPRERGKAMAIFLGGSAFAS
VLSGPVTGALLSIRGLGLEGWQWMFIIEGLFSIALCGRSWVLLKSHIRDATWLDAQERAALEQALDEERARRDVRANGHV
PALALLRDPQIVLFCFLYFSIQLTIYAATFWLPTIIRKMGGLSDFQVGLYNTIPWMIAIGAMYGFAVLSAKWRHPQRWLA
CALVLAACGLFASTSPDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSIGNLGGFVAPTAFGYLKQH
TGSITGGLYALAIASLVAAFAALFARTHRRSDPPRGLPAADTVTNASMLRHAEH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=22.737819025522, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367379, Length=441, Percent_Identity=23.8095238095238, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=24.4343891402715, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=21.9858156028369, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367193, Length=313, Percent_Identity=21.405750798722, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=237, Percent_Identity=23.6286919831224, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=294, Percent_Identity=22.7891156462585, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639764, Length=385, Percent_Identity=25.4545454545455, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641682, Length=380, Percent_Identity=26.0526315789474, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20130167, Length=374, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654215, Length=370, Percent_Identity=21.8918918918919, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49403; Mature: 49272

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPAPALPERDPLASAVSKVKWHVLPLVLVMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYVLRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGAAEAGFFPGVVLYLSQWLPPRERGKAMAIFLGGSAFASVLSGPVTGALLSIRGLGLE
HHHHHHCCCHHHHHHHHHHCCCCHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFIIEGLFSIALCGRSWVLLKSHIRDATWLDAQERAALEQALDEERARRDVRANGH
CHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
VPALALLRDPQIVLFCFLYFSIQLTIYAATFWLPTIIRKMGGLSDFQVGLYNTIPWMIAI
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GAMYGFAVLSAKWRHPQRWLACALVLAACGLFASTSPDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSIGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FAALFARTHRRSDPPRGLPAADTVTNASMLRHAEH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPAPALPERDPLASAVSKVKWHVLPLVLVMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYVLRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGAAEAGFFPGVVLYLSQWLPPRERGKAMAIFLGGSAFASVLSGPVTGALLSIRGLGLE
HHHHHHCCCHHHHHHHHHHCCCCHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFIIEGLFSIALCGRSWVLLKSHIRDATWLDAQERAALEQALDEERARRDVRANGH
CHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
VPALALLRDPQIVLFCFLYFSIQLTIYAATFWLPTIIRKMGGLSDFQVGLYNTIPWMIAI
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GAMYGFAVLSAKWRHPQRWLACALVLAACGLFASTSPDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSIGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FAALFARTHRRSDPPRGLPAADTVTNASMLRHAEH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]