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The map label for this gene is pgl [H]

Identifier: 161524266

GI number: 161524266

Start: 1191177

End: 1192223

Strand: Reverse

Name: pgl [H]

Synonym: Bmul_1090

Alternate gene names: 161524266

Gene position: 1192223-1191177 (Counterclockwise)

Preceding gene: 161524267

Following gene: 161524264

Centisome position: 34.57

GC content: 72.97

Gene sequence:

>1047_bases
ATGCCGAACACTGACCTTCCGACCGTCGTCGTGTCGAACGCCCTCGACGGTGACCTAGCCACCTTCTCGCTCGCGCACGA
CGGCACGCTCGCGCCGCTCGCGCGCTATCCGGCCGGCGACGCCACGATGCCGATCGCCGTGCAAGCCGACCGCGCGCGGC
TGTACGTCGCGACGCGCGGCGAGTCGCCTGCGATCGTCGCGTTCCGCGTCGCACCGACCGGCGCGCTCGCGCGGATCGGC
ACGACCGCGATCGATGCGAGCCTCGCCTATCTGTCGGTCGACGGCAGCGGCCGCTGGCTGCTCGGCGCGTCGTACGGCGG
CCACGCGTTCAGCGTCTACGATGCCGCGCGCGTGCGCGACGGCGACGGCGCGCCGCTGCACGTCGCCAATGGCATTGCGA
ACGCGCATGCGGTCATCGTCTCGCCCGACAACCGCTTTGCGTACGTCAGCTCGCTCGGCTCCGATCGCGTGTTCTGTTTC
GCACTGATCGAGGATGCGGCCGGGCTGCGCGTGTGCGAGCAAGGCGAAGCGCGCGTGCCGGCCGGTTTCGGGCCGCGTCA
TCTGCGGTTCATGGAGGGCGGCCGCGCGCTCGTCGCGGTCAGCGAATTCCACGGCATGCTCGCGACGTTCGCGCGCGATG
CCGACAGCGGCCGGCTCGGCGATGCGCAGGTCAGCGCGCGTCACCCGGCCGTCGCGGGACTCCCGGCCGGCCATGCACGA
CCGCCCGCCCCGGCCGAGCCCGCCGTCTGGGCCGCCGATCTGCACCTGACGCCCGACGAGCGCTTCGCGTACGTCAGCGA
GCGCACGACGAGCCAGCTGCTCTGCTATCGCCGCAGCGCGGACGGCCGGTTCGAGCCCGCGCATGCGACCGCCACGGAAA
CGCAGCCGCGCGGCTTCGCGATCGATCCGTCGGGACGCTGGCTCGTCGCGTGCGGCGAACGCTCGGAGCACGTGGCGGTG
TACGGCGTGTCGCGCGACGACGGCACGCTGACGCTGCATGCGCGCGTGCCCGGCGGGCGCGGCGCGAACTGGATCGCGAT
CGTCTGA

Upstream 100 bases:

>100_bases
GCCGCGTTCGCCGCACTGTTCGCGCGCACGCACCGGCGCAGCGATCCGCCGCGCGGCCTGCCCGCCGCCGATACCGTAAC
CAACGCTTCGATGCTCCGCC

Downstream 100 bases:

>100_bases
TCGCGCACGGCCCGGCGTGCGGCGTGCTCAGCGCCGCGCGCTCGGTGCGTGAGCGGCCGCGTCAGTCGCCAATCGGCGGC
ATCGGCTGCCGTCCGCGAAT

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6-P-gluconolactonase [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPNTDLPTVVVSNALDGDLATFSLAHDGTLAPLARYPAGDATMPIAVQADRARLYVATRGESPAIVAFRVAPTGALARIG
TTAIDASLAYLSVDGSGRWLLGASYGGHAFSVYDAARVRDGDGAPLHVANGIANAHAVIVSPDNRFAYVSSLGSDRVFCF
ALIEDAAGLRVCEQGEARVPAGFGPRHLRFMEGGRALVAVSEFHGMLATFARDADSGRLGDAQVSARHPAVAGLPAGHAR
PPAPAEPAVWAADLHLTPDERFAYVSERTTSQLLCYRRSADGRFEPAHATATETQPRGFAIDPSGRWLVACGERSEHVAV
YGVSRDDGTLTLHARVPGGRGANWIAIV

Sequences:

>Translated_348_residues
MPNTDLPTVVVSNALDGDLATFSLAHDGTLAPLARYPAGDATMPIAVQADRARLYVATRGESPAIVAFRVAPTGALARIG
TTAIDASLAYLSVDGSGRWLLGASYGGHAFSVYDAARVRDGDGAPLHVANGIANAHAVIVSPDNRFAYVSSLGSDRVFCF
ALIEDAAGLRVCEQGEARVPAGFGPRHLRFMEGGRALVAVSEFHGMLATFARDADSGRLGDAQVSARHPAVAGLPAGHAR
PPAPAEPAVWAADLHLTPDERFAYVSERTTSQLLCYRRSADGRFEPAHATATETQPRGFAIDPSGRWLVACGERSEHVAV
YGVSRDDGTLTLHARVPGGRGANWIAIV
>Mature_347_residues
PNTDLPTVVVSNALDGDLATFSLAHDGTLAPLARYPAGDATMPIAVQADRARLYVATRGESPAIVAFRVAPTGALARIGT
TAIDASLAYLSVDGSGRWLLGASYGGHAFSVYDAARVRDGDGAPLHVANGIANAHAVIVSPDNRFAYVSSLGSDRVFCFA
LIEDAAGLRVCEQGEARVPAGFGPRHLRFMEGGRALVAVSEFHGMLATFARDADSGRLGDAQVSARHPAVAGLPAGHARP
PAPAEPAVWAADLHLTPDERFAYVSERTTSQLLCYRRSADGRFEPAHATATETQPRGFAIDPSGRWLVACGERSEHVAVY
GVSRDDGTLTLHARVPGGRGANWIAIV

Specific function: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate [H]

COG id: COG2706

COG function: function code G; 3-carboxymuconate cyclase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cycloisomerase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786983, Length=350, Percent_Identity=29.4285714285714, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022528
- InterPro:   IPR019405
- InterPro:   IPR011045
- InterPro:   IPR015943 [H]

Pfam domain/function: PF10282 DUF2394 [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 36513; Mature: 36382

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTDLPTVVVSNALDGDLATFSLAHDGTLAPLARYPAGDATMPIAVQADRARLYVATRG
CCCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEEEECCEEEEEEECC
ESPAIVAFRVAPTGALARIGTTAIDASLAYLSVDGSGRWLLGASYGGHAFSVYDAARVRD
CCCEEEEEEECCCCCHHHCCCCEEEEEEEEEEECCCCCEEEEECCCCCEEEEEEHEEEEC
GDGAPLHVANGIANAHAVIVSPDNRFAYVSSLGSDRVFCFALIEDAAGLRVCEQGEARVP
CCCCEEEEECCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCC
AGFGPRHLRFMEGGRALVAVSEFHGMLATFARDADSGRLGDAQVSARHPAVAGLPAGHAR
CCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEECCCCCCCC
PPAPAEPAVWAADLHLTPDERFAYVSERTTSQLLCYRRSADGRFEPAHATATETQPRGFA
CCCCCCCCEEEEEEEECCHHHEEEEHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEE
IDPSGRWLVACGERSEHVAVYGVSRDDGTLTLHARVPGGRGANWIAIV
ECCCCCEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCCCCEEEEC
>Mature Secondary Structure 
PNTDLPTVVVSNALDGDLATFSLAHDGTLAPLARYPAGDATMPIAVQADRARLYVATRG
CCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHCCCCCCCEEEEEEECCEEEEEEECC
ESPAIVAFRVAPTGALARIGTTAIDASLAYLSVDGSGRWLLGASYGGHAFSVYDAARVRD
CCCEEEEEEECCCCCHHHCCCCEEEEEEEEEEECCCCCEEEEECCCCCEEEEEEHEEEEC
GDGAPLHVANGIANAHAVIVSPDNRFAYVSSLGSDRVFCFALIEDAAGLRVCEQGEARVP
CCCCEEEEECCCCCCEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCC
AGFGPRHLRFMEGGRALVAVSEFHGMLATFARDADSGRLGDAQVSARHPAVAGLPAGHAR
CCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCEEECCCCCEECCCCCCCC
PPAPAEPAVWAADLHLTPDERFAYVSERTTSQLLCYRRSADGRFEPAHATATETQPRGFA
CCCCCCCCEEEEEEEECCHHHEEEEHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEE
IDPSGRWLVACGERSEHVAVYGVSRDDGTLTLHARVPGGRGANWIAIV
ECCCCCEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA