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The map label for this gene is ybdL [H]

Identifier: 161524228

GI number: 161524228

Start: 1147279

End: 1148451

Strand: Reverse

Name: ybdL [H]

Synonym: Bmul_1052

Alternate gene names: 161524228

Gene position: 1148451-1147279 (Counterclockwise)

Preceding gene: 161524229

Following gene: 161524226

Centisome position: 33.3

GC content: 65.81

Gene sequence:

>1173_bases
ATGAACGCTCCCTCCGACATGCCAACGTCCCCCGTTTTCCCGTCGCGCCTGCCGAACGTCGGCACGACGATCTTCACGGT
CATGAGCGCGCTCGCCGCCGAAAAAGGCGCGGTGAATCTCGGGCAGGGCTTTCCGGATTTCGACTGCGACCCGCGCATCG
TCGACGCAGTGGCGGCCGCGATGCGCAGCGGCCACAACCAGTACCCGCCGATGGCGGGCGTCGCGCCGCTGCGCGAAGCG
ATCGCGGACAAGATCGCGCAGCTCTACGGCCGCCGCTACGATGCCGGCACCGAAATCACCGTGACGGCCGGCGCGACGCA
GGCGCTGCTGACGGCCATCCTGTGCGCCGTGCATCCGGGCGACGAAGTGATCGTCGTCGAGCCGACCTACGACAGCTATC
TGCCGTCGATCGAACTCGCCGGCGGCAAGCCCGTCTTCGTCACGCTCGAAGCGCCGGACTACACGATTCCGTTCGACCGT
CTCGCGGCCGCGATCACGCCGAACACGCGGATGATCCTGATCAACACGCCGCACAACCCGACCGGCACCGTGTGGCGCGA
AGCGGACATGCGCAAGCTCGAGGACATCGTGCGCGGCACCAACGTGCTGATCCTGTCGGACGAGGTGTACGAGCACATGG
TCTACGACGGCGAGCGTCACGAAAGCGTCGCGCGCTATCCGGAACTCGCCGCACGCAGCTTCATCGTGTCGAGCTTCGGC
AAGACGTATCACGTGACGGGCTGGAAGGTCGGCTACGTCGCGGCACCGGCCGCGCTGACTGCCGAATTCCGCAAGGTCCA
TCAGTTCAACGTGTTTACGGTCAATACGCCGATGCAAATCGGCCTCGCCGACTATCTGCGCGATCCGGCGCCGTACCTGA
CGCTCGCGGGCTTCTATCAGAACAAGCGCGACTTCTTCCGCGCGGGCCTCGAACGCACGCGCTTCAAGCTGCTGCCGTGC
TCGGGCACGTACTTCCAGTGCGTCGACTATTCGGCGATCAGCGATCTGCCGGAAGCGGAATTCTCGAAGTGGCTGACGTC
GGAGATCGGCGTGGCCGCGATTCCGGTGTCGGCGTTCTATCACGAGCCGCACGAGTCGGGCGTCGTGCGCTTCTGCTTCG
CGAAGCAGGAGAGCACGCTCGCGACCGCGCTCGAGCGGCTCGCGCGCCTGTAA

Upstream 100 bases:

>100_bases
CAACCCGCACCGTTTACCGAGGCCTGCGCGCTCGCCGCCGCAACGGCCGCCACTGTCACGCCGGCCTGACGCTGCCGGCA
TCACCACTTCGACCGTACCG

Downstream 100 bases:

>100_bases
CGCGCCGGCCGGGTGCGGCACTCGTCGGCGCGCGGCGCCTGGCGATGCCGCGCTCGCGTGGGCAATGCACCTCGCCCGCA
TGCGACGCGGCCACCGGCAC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNAPSDMPTSPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRSGHNQYPPMAGVAPLREA
IADKIAQLYGRRYDAGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYTIPFDR
LAAAITPNTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGERHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQNKRDFFRAGLERTRFKLLPC
SGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLATALERLARL

Sequences:

>Translated_390_residues
MNAPSDMPTSPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRSGHNQYPPMAGVAPLREA
IADKIAQLYGRRYDAGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYTIPFDR
LAAAITPNTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGERHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQNKRDFFRAGLERTRFKLLPC
SGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLATALERLARL
>Mature_390_residues
MNAPSDMPTSPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRSGHNQYPPMAGVAPLREA
IADKIAQLYGRRYDAGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYTIPFDR
LAAAITPNTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGERHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQNKRDFFRAGLERTRFKLLPC
SGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLATALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=34.4743276283619, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=34.4743276283619, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=33.8308457711443, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=33.9152119700748, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=30.1470588235294, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI4507369, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=51.5544041450777, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.065963060686, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788627, Length=219, Percent_Identity=30.1369863013699, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1787710, Length=306, Percent_Identity=28.1045751633987, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=35.1485148514851, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=35.1485148514851, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17567369, Length=406, Percent_Identity=31.5270935960591, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17567663, Length=203, Percent_Identity=25.615763546798, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=33.3333333333333, Blast_Score=196, Evalue=5e-51,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=34.7931873479319, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=34.7931873479319, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=34.7931873479319, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=34.7931873479319, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI18859735, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42840; Mature: 42840

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPSDMPTSPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRSGHNQYPPMAGVAPLREAIADKIAQLYGRRYDAGTEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYTIPFDRLAAAITPNTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEEECCCCCCCHHHHHHEECCCCEEEEEECCCCC
TGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGERHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQ
CEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEEEHHHHH
NKRDFFRAGLERTRFKLLPCSGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
CHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLATALERLARL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPSDMPTSPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRSGHNQYPPMAGVAPLREAIADKIAQLYGRRYDAGTEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYTIPFDRLAAAITPNTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEEECCCCCCCHHHHHHEECCCCEEEEEECCCCC
TGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGERHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLTLAGFYQ
CEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCCEEEHHHHH
NKRDFFRAGLERTRFKLLPCSGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
CHHHHHHHHHHHCEEEEEECCCCEEEEECCHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLATALERLARL
CCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]