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The map label for this gene is paaF [H]

Identifier: 161524226

GI number: 161524226

Start: 1145519

End: 1146310

Strand: Reverse

Name: paaF [H]

Synonym: Bmul_1050

Alternate gene names: 161524226

Gene position: 1146310-1145519 (Counterclockwise)

Preceding gene: 161524228

Following gene: 161524225

Centisome position: 33.24

GC content: 69.82

Gene sequence:

>792_bases
ATGAGTGCCGAACTGCTGGCCACGCGCCCGCCCGAGAGCGAATCGACGCTCGTCCTCACGATCTCGAATCCCGGCGCACG
CAACGCGCTGCATCCCGACATGTACGCGGCCGGCGTCGAAGCGCTCGCGACCGCCGAGCGCGACCCGAGCATTCGCGCGG
TCGTGCTCACGGGTGCCGATCGTTTCTTCTGCGCCGGCGGCAACCTGAACCGGCTGCTCGACAACCGATCGAAGGACCCG
TCGTTCCAGGCCGCCAGCATCGATCAGCTCGCCGCGTGGGTGGCCGCGATCCACGCCTCGACGAAACCGGTGATCGCCGC
AGTCGAAGGCGCGGCAGCCGGCGCGGGCTTCTCGCTCGCACTCGCCTGCGACCTGATCGTTGCCGCGCACGACGCGAAGT
TCGCGATGTCGTACGCGCGGGTGGGCCTCACGCCCGACGGCGGCGGTTCGTGGTTCCTCGCCCGTGCATTGCCGCGCGCG
CTGGCGGCCGAAATCCTGCTCGAAGGCAAGCCGGTCGCTGCCGAACGCCTGCACGCGCTCGGCGTCGTCAACCGGCTCGC
GACACCGGGCGCCGCGCTGACCGATGCGCTCGCGTGGGCCGACACGCTCGCCGGCATCTCGCCGAATGCGCTGACGCGCA
TCAAGACGCTGCTCGACGATGCGCTCGCGCAGCCGCTCGAGTCGCACCTCGGCACGGAGCGCGATCATTTCGTCGCGTCG
CTGCATCATCCGGACGCGCTCGAAGGCATCACCGCGTTTCTCGACAAGCGTCAGCCGCACTACAAGCGCTGA

Upstream 100 bases:

>100_bases
CGCCGTCACGACAACATTGCATCCGCCGAAGCAGCCGCTTCGTCTGCCGCCGCACCGAACGCGGCGCGGCCGCCTCGCCA
TCCGATGGAGACACGCTCGC

Downstream 100 bases:

>100_bases
CGCCACGCCGCCGTGCGCGCGGCGCCCCTCCGCGCGTCGAGGCAAGCCCTGCAGCGCGCATCGATCCGTGCTGTAATGAC
CGCCTGCCGCGGCGCGCGCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSAELLATRPPESESTLVLTISNPGARNALHPDMYAAGVEALATAERDPSIRAVVLTGADRFFCAGGNLNRLLDNRSKDP
SFQAASIDQLAAWVAAIHASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFAMSYARVGLTPDGGGSWFLARALPRA
LAAEILLEGKPVAAERLHALGVVNRLATPGAALTDALAWADTLAGISPNALTRIKTLLDDALAQPLESHLGTERDHFVAS
LHHPDALEGITAFLDKRQPHYKR

Sequences:

>Translated_263_residues
MSAELLATRPPESESTLVLTISNPGARNALHPDMYAAGVEALATAERDPSIRAVVLTGADRFFCAGGNLNRLLDNRSKDP
SFQAASIDQLAAWVAAIHASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFAMSYARVGLTPDGGGSWFLARALPRA
LAAEILLEGKPVAAERLHALGVVNRLATPGAALTDALAWADTLAGISPNALTRIKTLLDDALAQPLESHLGTERDHFVAS
LHHPDALEGITAFLDKRQPHYKR
>Mature_262_residues
SAELLATRPPESESTLVLTISNPGARNALHPDMYAAGVEALATAERDPSIRAVVLTGADRFFCAGGNLNRLLDNRSKDPS
FQAASIDQLAAWVAAIHASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFAMSYARVGLTPDGGGSWFLARALPRAL
AAEILLEGKPVAAERLHALGVVNRLATPGAALTDALAWADTLAGISPNALTRIKTLLDDALAQPLESHLGTERDHFVASL
HHPDALEGITAFLDKRQPHYKR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=258, Percent_Identity=29.8449612403101, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI31542718, Length=241, Percent_Identity=27.8008298755187, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI221307494, Length=217, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136756, Length=217, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136753, Length=217, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502327, Length=257, Percent_Identity=28.0155642023346, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI116235487, Length=213, Percent_Identity=28.6384976525822, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4757966, Length=216, Percent_Identity=27.3148148148148, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=216, Percent_Identity=27.3148148148148, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=216, Percent_Identity=27.3148148148148, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=216, Percent_Identity=27.3148148148148, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757968, Length=216, Percent_Identity=27.3148148148148, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI49355787, Length=216, Percent_Identity=27.3148148148148, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI70995211, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI45643119, Length=207, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI260275230, Length=207, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI260274832, Length=207, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=26.7045454545455, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=36.7424242424242, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI221142681, Length=267, Percent_Identity=34.0823970037453, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787660, Length=254, Percent_Identity=36.2204724409449, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788597, Length=248, Percent_Identity=29.8387096774194, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082183, Length=242, Percent_Identity=26.8595041322314, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788682, Length=171, Percent_Identity=32.1637426900585, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=31.1023622047244, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=31.1023622047244, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=176, Percent_Identity=31.8181818181818, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=256, Percent_Identity=26.953125, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=244, Percent_Identity=24.1803278688525, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=21.7898832684825, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=254, Percent_Identity=25.5905511811024, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=259, Percent_Identity=24.7104247104247, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=251, Percent_Identity=30.2788844621514, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24653477, Length=251, Percent_Identity=30.2788844621514, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24653139, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654903, Length=243, Percent_Identity=25.1028806584362, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920382, Length=206, Percent_Identity=29.126213592233, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357171, Length=204, Percent_Identity=26.9607843137255, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571730, Length=155, Percent_Identity=31.6129032258064, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571729, Length=155, Percent_Identity=31.6129032258064, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27530; Mature: 27398

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAELLATRPPESESTLVLTISNPGARNALHPDMYAAGVEALATAERDPSIRAVVLTGAD
CCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCC
RFFCAGGNLNRLLDNRSKDPSFQAASIDQLAAWVAAIHASTKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LACDLIVAAHDAKFAMSYARVGLTPDGGGSWFLARALPRALAAEILLEGKPVAAERLHAL
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLATPGAALTDALAWADTLAGISPNALTRIKTLLDDALAQPLESHLGTERDHFVAS
HHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEE
LHHPDALEGITAFLDKRQPHYKR
CCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAELLATRPPESESTLVLTISNPGARNALHPDMYAAGVEALATAERDPSIRAVVLTGAD
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCC
RFFCAGGNLNRLLDNRSKDPSFQAASIDQLAAWVAAIHASTKPVIAAVEGAAAGAGFSLA
EEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
LACDLIVAAHDAKFAMSYARVGLTPDGGGSWFLARALPRALAAEILLEGKPVAAERLHAL
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVVNRLATPGAALTDALAWADTLAGISPNALTRIKTLLDDALAQPLESHLGTERDHFVAS
HHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEE
LHHPDALEGITAFLDKRQPHYKR
CCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]