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The map label for this gene is tpiA [H]

Identifier: 161524202

GI number: 161524202

Start: 1123107

End: 1123862

Strand: Direct

Name: tpiA [H]

Synonym: Bmul_1026

Alternate gene names: 161524202

Gene position: 1123107-1123862 (Clockwise)

Preceding gene: 161524201

Following gene: 161524203

Centisome position: 32.57

GC content: 69.71

Gene sequence:

>756_bases
ATGTCGAAACAGAGAACAAAGCGGGTGATCGGCAACTGGAAGATGCACGGCCGGCTGGCCGGCAACCAGGCGTTGCTGAA
CGAAGTGGTACAGGGCGCGGGCGCCGCGGCGGCCGACACGGCGATCGGCGTGTGCGTGCCGTTCCCGTATCTCGCGCAGG
TTCAGGCGCAGCTCGGCGGCAGCCGTATCGCATGGGGCGCGCAGGACGTGTCGGCACACGAGCAGGGCGCGTTTACCGGC
GAAGTCGCGGCGGCGATGGTTGCCGAATTCGGTGCGTGCTACGCGATCGTCGGTCACTCGGAGCGCCGCGCGTATCACGG
CGAGCGCAACGAGACGGTCGCGGCGAAGACGCAGCGTGCGCTTGCCGCGGGGCTGACGCCCGTCGTTTGCGTCGGCGAGA
CGCTCGAGCAGCGCGAATCGGGCGCGACCGAGCAGGTCGTCGGCGCGCAGCTCGATGCCGTGCTCGCGGTGTTGAGCGCG
GACGAAGCAGCGCGCATCGTCGTCGCGTACGAACCGGTGTGGGCGATCGGCACCGGCAAGAGCGCGACGTCCGCGCAGGC
GCAGGACGTGCACGCATTCCTGCGCGCGCGGCTCGCGGCCAAGGGTGCGGCCGACGTATCGGTGCTGTACGGCGGCAGCG
TGAAGCCGGACAACGCGGAAGAACTGTTCGCACAGCCGGACATCGACGGCGGCCTGATCGGCGGCGCGTCGCTGAAGGCG
GAAGATTTTCTGGCGATCTGCCGGGCCGCGCGTTGA

Upstream 100 bases:

>100_bases
TTGACCGGTTCAAGCCGCGCGCAGTAAAATCGCGGGTTTGCTTCGCCAGATCAAACCTGACGGCCGGCTCGCACGGCACG
TCGATGACGAGACAGACACG

Downstream 100 bases:

>100_bases
GCGGTCGGCGATCGAATTGAACCATGACGGCGGCCGGCAAGTCCGGTCGCCCGATCCAATCGGGTGGATGTGATGCTGTT
ATTCAAGACGCTGATTATTG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAAAADTAIGVCVPFPYLAQVQAQLGGSRIAWGAQDVSAHEQGAFTG
EVAAAMVAEFGACYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLEQRESGATEQVVGAQLDAVLAVLSA
DEAARIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
EDFLAICRAAR

Sequences:

>Translated_251_residues
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAAAADTAIGVCVPFPYLAQVQAQLGGSRIAWGAQDVSAHEQGAFTG
EVAAAMVAEFGACYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLEQRESGATEQVVGAQLDAVLAVLSA
DEAARIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
EDFLAICRAAR
>Mature_250_residues
SKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAAAADTAIGVCVPFPYLAQVQAQLGGSRIAWGAQDVSAHEQGAFTGE
VAAAMVAEFGACYAIVGHSERRAYHGERNETVAAKTQRALAAGLTPVVCVGETLEQRESGATEQVVGAQLDAVLAVLSAD
EAARIVVAYEPVWAIGTGKSATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKAE
DFLAICRAAR

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=255, Percent_Identity=41.5686274509804, Blast_Score=177, Evalue=9e-45,
Organism=Homo sapiens, GI226529917, Length=257, Percent_Identity=42.0233463035019, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI1790353, Length=253, Percent_Identity=48.6166007905138, Blast_Score=218, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17536593, Length=245, Percent_Identity=45.3061224489796, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=251, Percent_Identity=39.8406374501992, Blast_Score=171, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28572004, Length=244, Percent_Identity=44.672131147541, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI28572008, Length=244, Percent_Identity=44.672131147541, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28572006, Length=244, Percent_Identity=44.672131147541, Blast_Score=183, Evalue=9e-47,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25940; Mature: 25808

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAAAADTAIGVCVPFPYLAQVQAQLGG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCC
SRIAWGAQDVSAHEQGAFTGEVAAAMVAEFGACYAIVGHSERRAYHGERNETVAAKTQRA
CEEECCCCCCCHHHCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCCHHHHHHHHH
LAAGLTPVVCVGETLEQRESGATEQVVGAQLDAVLAVLSADEAARIVVAYEPVWAIGTGK
HHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCC
SATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCEECCCCCCH
EDFLAICRAAR
HHHHHHHHCCC
>Mature Secondary Structure 
SKQRTKRVIGNWKMHGRLAGNQALLNEVVQGAGAAAADTAIGVCVPFPYLAQVQAQLGG
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCC
SRIAWGAQDVSAHEQGAFTGEVAAAMVAEFGACYAIVGHSERRAYHGERNETVAAKTQRA
CEEECCCCCCCHHHCCCCHHHHHHHHHHHHCCEEEEECCCHHHHHCCCCCCHHHHHHHHH
LAAGLTPVVCVGETLEQRESGATEQVVGAQLDAVLAVLSADEAARIVVAYEPVWAIGTGK
HHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCC
SATSAQAQDVHAFLRARLAAKGAADVSVLYGGSVKPDNAEELFAQPDIDGGLIGGASLKA
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHCCCCCCCCEECCCCCCH
EDFLAICRAAR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA