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The map label for this gene is mas [H]

Identifier: 161524201

GI number: 161524201

Start: 1121955

End: 1122974

Strand: Direct

Name: mas [H]

Synonym: Bmul_1025

Alternate gene names: 161524201

Gene position: 1121955-1122974 (Clockwise)

Preceding gene: 161524200

Following gene: 161524202

Centisome position: 32.53

GC content: 69.41

Gene sequence:

>1020_bases
ATGAAAGCGATCGAAATCACCGAATTCGGCGCCCCCGACGTGCTGAAGCTGACGGAGCGCCCGCGCCCCGAACCGCAGCG
CGGCGAAGTGCTGATCAAGGTGGCGGCGTCCGGCGTGAACCGGCCCGACGTGTTCCAGCGCAAGGGGGCGTATGCGCCGC
CGCCGGGTGCGTCCGATCTGCCGGGTCTCGAGATCGCGGGCGAAATCGTCGGCGGCGATCTGTCCGACGCCGCGCTGAAT
CCGTTCGGCCTGAAGCTCGGCGACCGCGTCTGCGCGCTGCTCGCGGGCGGCGGCTATGCCGAATACGCGACCGTGCCGCT
GCTGCAGTGTCTGCCGGTGCCGCGCGGCCTCACCGACATCGAAGCGGCGTCGTTGCCCGAGACGTTCTTTACGGTGTGGA
GCAACGTGTTCGATCGCGCGCAGCTCGGCGCGGGCGAGGGCGGCGAGCAGGAAACGCTGCTCGTGCAGGGCGGCTCGAGC
GGCATCGGCGTGACGGCGATCCAGATCGCGCATGCGCTCGGCTTTCGCGTGTTCGCGACGGCCGGCACGGCGGAGAAGTG
CCGCGCGTGCGAGGCGCTCGGCGCGGAGCGCGCGATCGACTACAAGACCGAGGACTTCGTCGAAGTCGTGAAGTCGCTGA
CCAACGATCGCGGCGTCGACGTGATTCTCGACATGGTCGCGGGCTCTTACGTGCCGCGCGAACTCTCGGCGCTGGCCGAC
GGCGGGCGGCTCGTGATCATCGCGCTGCTCGGCGGCGCGAAGGCCGAAGTCAATCTCGGCGAGATCCTGCGCCGCCGGCT
GACGATCACGGGCTCGACGCTGCGTCCGCGGCCGGTCGAGTTCAAGGCGCAGATCGCGGCGCAGCTCAAGGCGCGCGTGT
GGCCGCTGATCGAGGACGGCCGCATCAAGCCCGTCATCTATCGCGTGCTGCCGGCCGCCGACGCTGCGCAGGCGCATGCG
CTGATGGAAAGCAGCGAGCACATCGGCAAGATCGTGCTCGATTGGGGTACGAGCGCGTAA

Upstream 100 bases:

>100_bases
GCCGTTTTTTCTGTAGCATCGTTGTGCGGCGCAGCAGCGCCGGCCATGCGTCCGCGGGCGGCGGACGCGCATCCGATCCC
GACCCAGGAGCGACGAAACC

Downstream 100 bases:

>100_bases
CGGCCGCGGTTGCCGGGCTTGACATGCGCGGTTTGACCGGTTCAAGCCGCGCGCAGTAAAATCGCGGGTTTGCTTCGCCA
GATCAAACCTGACGGCCGGC

Product: PIG3 family NAD(P)H quinone oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKAIEITEFGAPDVLKLTERPRPEPQRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEIAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYATVPLLQCLPVPRGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTAEKCRACEALGAERAIDYKTEDFVEVVKSLTNDRGVDVILDMVAGSYVPRELSALAD
GGRLVIIALLGGAKAEVNLGEILRRRLTITGSTLRPRPVEFKAQIAAQLKARVWPLIEDGRIKPVIYRVLPAADAAQAHA
LMESSEHIGKIVLDWGTSA

Sequences:

>Translated_339_residues
MKAIEITEFGAPDVLKLTERPRPEPQRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEIAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYATVPLLQCLPVPRGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTAEKCRACEALGAERAIDYKTEDFVEVVKSLTNDRGVDVILDMVAGSYVPRELSALAD
GGRLVIIALLGGAKAEVNLGEILRRRLTITGSTLRPRPVEFKAQIAAQLKARVWPLIEDGRIKPVIYRVLPAADAAQAHA
LMESSEHIGKIVLDWGTSA
>Mature_339_residues
MKAIEITEFGAPDVLKLTERPRPEPQRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEIAGEIVGGDLSDAALN
PFGLKLGDRVCALLAGGGYAEYATVPLLQCLPVPRGLTDIEAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSS
GIGVTAIQIAHALGFRVFATAGTAEKCRACEALGAERAIDYKTEDFVEVVKSLTNDRGVDVILDMVAGSYVPRELSALAD
GGRLVIIALLGGAKAEVNLGEILRRRLTITGSTLRPRPVEFKAQIAAQLKARVWPLIEDGRIKPVIYRVLPAADAAQAHA
LMESSEHIGKIVLDWGTSA

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=37.0262390670554, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=37.0262390670554, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=33.2344213649852, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=33.2344213649852, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI194239676, Length=337, Percent_Identity=30.2670623145401, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI18379349, Length=352, Percent_Identity=29.2613636363636, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI24308257, Length=358, Percent_Identity=27.3743016759777, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=32.0652173913043, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI28557745, Length=285, Percent_Identity=28.4210526315789, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=28.125, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=358, Percent_Identity=27.0949720670391, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790485, Length=340, Percent_Identity=29.7058823529412, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17507255, Length=274, Percent_Identity=31.021897810219, Blast_Score=104, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6319520, Length=347, Percent_Identity=25.9365994236311, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=292, Percent_Identity=27.3972602739726, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=349, Percent_Identity=25.214899713467, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=344, Percent_Identity=25, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=349, Percent_Identity=24.3553008595989, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330659, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920632, Length=251, Percent_Identity=25.8964143426295, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24581345, Length=251, Percent_Identity=25.0996015936255, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 35812; Mature: 35812

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEITEFGAPDVLKLTERPRPEPQRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEIAGEIVGGDLSDAALNPFGLKLGDRVCALLAGGGYAEYATVPLLQCLPVPRGLTDI
CCCEEEHHHCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSSGIGVTAIQIAHALGFRVFAT
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTAEKCRACEALGAERAIDYKTEDFVEVVKSLTNDRGVDVILDMVAGSYVPRELSALAD
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCC
GGRLVIIALLGGAKAEVNLGEILRRRLTITGSTLRPRPVEFKAQIAAQLKARVWPLIEDG
CCCEEEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCEECCC
RIKPVIYRVLPAADAAQAHALMESSEHIGKIVLDWGTSA
CCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCC
>Mature Secondary Structure
MKAIEITEFGAPDVLKLTERPRPEPQRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEIAGEIVGGDLSDAALNPFGLKLGDRVCALLAGGGYAEYATVPLLQCLPVPRGLTDI
CCCEEEHHHCCCCCCHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGEQETLLVQGGSSGIGVTAIQIAHALGFRVFAT
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTAEKCRACEALGAERAIDYKTEDFVEVVKSLTNDRGVDVILDMVAGSYVPRELSALAD
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCC
GGRLVIIALLGGAKAEVNLGEILRRRLTITGSTLRPRPVEFKAQIAAQLKARVWPLIEDG
CCCEEEEEEECCCCCCCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCCEECCC
RIKPVIYRVLPAADAAQAHALMESSEHIGKIVLDWGTSA
CCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]