Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 161524068

GI number: 161524068

Start: 973807

End: 974724

Strand: Direct

Name: ompR [H]

Synonym: Bmul_0889

Alternate gene names: 161524068

Gene position: 973807-974724 (Clockwise)

Preceding gene: 161524066

Following gene: 161524069

Centisome position: 28.24

GC content: 69.28

Gene sequence:

>918_bases
ATGCGGCCGCGGGGCGACCCGGCTGCCGCATCCGGTAAGACGCAGGTTAGCGGCGCAGGCGCCGGCCGATGTTACGCGGG
GTGGCGGCCGGGTTACCGCCCATTACAGTTGGCTTGCACGGTAATCCGCAGTAACCCTTTCGTCCCTTTGTTTCGTTCTT
CGACGCCGCCCGTGCGCGGTAAACTTCGAGCCATGACTACCCAGATCCTCATCGTCGACGACGACCAAGAACTCCGCGAC
CTGCTGCGCGACTATCTCGTGCGCCAGGGGATGGAAGTGTCCGTGCTGCACGACGCGGCAACGCTCGAAAAGCGCCTCGA
GCGCGAGCGCCCCGACCTCATCGTGCTCGACCTCATGATGCCGGGCGTGGACGGCCTCACCGCGCTGCGCCAGCTGCGCG
CGGCGGGCGACGACATCCCCGTGATCATGCTGACCGCGCGCGCGGACGACGTGGACCGCATCGTCGGGCTCGAGCTCGGC
GCGGACGATTACCTCGGCAAGCCGTTCAATCCGCGCGAGCTGCTCGCACGCGTGCAGGCCGTGCTGCGCCGCCGCCGCGC
GACGCCGTCGGCCGCCGCGCCCGAGCAGCGCGAGCCGTTCGCGTTCGGCCGCTTCGTGCTCGATTTCCAGGCGCGCACGC
TGTCGATCGACGGCAAGCCGGCGACGCTGTCGAGCAGCGAATTCGCGCTGCTGAAGATCTTCGTGAACCACGCGCTGCGC
ACGCTCACGCGCGAGCGGCTGCTCGAGCTGCTGCACGGGCCCGAGTACGACGGTACCGACCGCGGCATCGACGTCCAGGT
GTGGCGCCTGCGCCGCATCCTCGAGACCGATCCGTCGACGCCGCGCTTCATCCAGACGGTCCGCGGGCGCGGCTACGTGT
TCGTGCCCGACGGCGAGGCCCATGCGCAAACCCATTGA

Upstream 100 bases:

>100_bases
CGGTGCCGAATGCGAGGGCGAGCACGGTGGCGGCCGCCATGGCCACGCGGGAAGTCTTCTTATACATTTCAGAAACTCCT
TGTATTCAGAGGGTCCGGCG

Downstream 100 bases:

>100_bases
TTCGCTGTTCGGCCGGCTCGCGCTGCTTGTCGTCGGCGTGCTGCTGCTGTCGCACTTCGCGTGGTATTTCGCGATGCGGC
TCGAACGCAATCAGATGCAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRPRGDPAAASGKTQVSGAGAGRCYAGWRPGYRPLQLACTVIRSNPFVPLFRSSTPPVRGKLRAMTTQILIVDDDQELRD
LLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELG
ADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFVLDFQARTLSIDGKPATLSSSEFALLKIFVNHALR
TLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQTH

Sequences:

>Translated_305_residues
MRPRGDPAAASGKTQVSGAGAGRCYAGWRPGYRPLQLACTVIRSNPFVPLFRSSTPPVRGKLRAMTTQILIVDDDQELRD
LLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELG
ADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFVLDFQARTLSIDGKPATLSSSEFALLKIFVNHALR
TLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQTH
>Mature_305_residues
MRPRGDPAAASGKTQVSGAGAGRCYAGWRPGYRPLQLACTVIRSNPFVPLFRSSTPPVRGKLRAMTTQILIVDDDQELRD
LLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMMPGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELG
ADDYLGKPFNPRELLARVQAVLRRRRATPSAAAPEQREPFAFGRFVLDFQARTLSIDGKPATLSSSEFALLKIFVNHALR
TLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEAHAQTH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=52.1367521367521, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=37.9310344827586, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=39.1489361702128, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=35.8649789029536, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=40.7725321888412, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=35.1931330472103, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.8974358974359, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.3390557939914, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=38.6266094420601, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=34.9557522123894, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=37.0044052863436, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=34.2105263157895, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.0884955752212, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=33.1896551724138, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.042735042735, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=35.0877192982456, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=126, Percent_Identity=31.7460317460317, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 34068; Mature: 34068

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRGDPAAASGKTQVSGAGAGRCYAGWRPGYRPLQLACTVIRSNPFVPLFRSSTPPVRG
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCHHH
KLRAMTTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMM
HHEEEEEEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
PGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQA
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHH
VLRRRRATPSAAAPEQREPFAFGRFVLDFQARTLSIDGKPATLSSSEFALLKIFVNHALR
HHHHHCCCCCCCCCCCCCCCHHHHEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
TLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCC
HAQTH
CCCCC
>Mature Secondary Structure
MRPRGDPAAASGKTQVSGAGAGRCYAGWRPGYRPLQLACTVIRSNPFVPLFRSSTPPVRG
CCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCHHH
KLRAMTTQILIVDDDQELRDLLRDYLVRQGMEVSVLHDAATLEKRLERERPDLIVLDLMM
HHEEEEEEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECC
PGVDGLTALRQLRAAGDDIPVIMLTARADDVDRIVGLELGADDYLGKPFNPRELLARVQA
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHH
VLRRRRATPSAAAPEQREPFAFGRFVLDFQARTLSIDGKPATLSSSEFALLKIFVNHALR
HHHHHCCCCCCCCCCCCCCCHHHHEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
TLTRERLLELLHGPEYDGTDRGIDVQVWRLRRILETDPSTPRFIQTVRGRGYVFVPDGEA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCCCC
HAQTH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]