Definition Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence.
Accession NC_010084
Length 3,448,466

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The map label for this gene is fhuC [H]

Identifier: 161524019

GI number: 161524019

Start: 916680

End: 917495

Strand: Direct

Name: fhuC [H]

Synonym: Bmul_0840

Alternate gene names: 161524019

Gene position: 916680-917495 (Clockwise)

Preceding gene: 161524018

Following gene: 161524020

Centisome position: 26.58

GC content: 72.06

Gene sequence:

>816_bases
ATGACCGCGGCCAGGTTCGATGCCGCAGAACAAGGCGCCTACGCAGCACGCGACCTGACGCTGAAGGCCGGCGCACGCAC
GCTGCTGGCGGCATTCACGCAGGTGTTCCGGCCCGGCGAAATCTGGTGCGTCGCGGGCCCGAACGGCGCCGGCAAGACGA
CGCTGCTCGCGACGCTGGCGGGGCTGCGGCCGCCGGCCGGCGGAGACGTCGAGATCGACGGCCGGCCGTTGTCCGCATGG
CCGCCCGCGCAACTTGCGCAGCGCCGCGCGCTGATGCCGCAGCAACTGCACGACGCATTCAGCGCGACGGTGTTCGACAC
GGTGCTGCTCAACCGCTTTCCGTATCTCGGCGGCTGGGGCTGGGAGCGCGACGGCGATCGCGAGGCGGCGCGCGCCGCGC
TCGCGACGTTCGGCCTCGGTGCGCTCGCCGGGCGCGACGTGCTGTCGCTGTCGGGCGGCGAGCGGCAGCGCGTCGCGCTG
GCGGCGACGCTGTGCCAGGACGCGCCGCTGATGCTGCTCGACGAGCCGCTCGCGCATCTCGATCTGCATCACCAGATCGA
CTGCCTGACCGCGCTGACCGACTGGGTTCGTGCGCGGCCGCGCACGGTGCTGTTCTCGTGCCACGACCTGAATCTCGCGC
GACGTTTCGCGACGCACGCGCTGCTGCTCGACGGCCGCGGTCAGGCATGGTCGGGGCCGGTATGCGACGTGCTCACGCCC
GAACGGGCGAGCGACGCGTTCGGCTATCCGCTCGTGCTGATCCGTGAAAACGGCCGCGATGCATTGCTGCCCGCGTGGCC
CGAGCGACGCGCATGA

Upstream 100 bases:

>100_bases
CGCGCAGCGCGATCGCGCCCGCGCAATTGCCGGTCGGCGTGATGACCGCGCTGATCGGCGTGCCGGTGTTCCTGTGGATG
TTGCTGAGGAGGCCGACACG

Downstream 100 bases:

>100_bases
TTTCCATTGTTCCGGCGTACGGCGCAAGCCGCGCCGACGAGGCTTCCCTTCGATGACCACTCCGACCGAATTCCTTCCGC
CGATCGCGCCGCTCGACGAA

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTAARFDAAEQGAYAARDLTLKAGARTLLAAFTQVFRPGEIWCVAGPNGAGKTTLLATLAGLRPPAGGDVEIDGRPLSAW
PPAQLAQRRALMPQQLHDAFSATVFDTVLLNRFPYLGGWGWERDGDREAARAALATFGLGALAGRDVLSLSGGERQRVAL
AATLCQDAPLMLLDEPLAHLDLHHQIDCLTALTDWVRARPRTVLFSCHDLNLARRFATHALLLDGRGQAWSGPVCDVLTP
ERASDAFGYPLVLIRENGRDALLPAWPERRA

Sequences:

>Translated_271_residues
MTAARFDAAEQGAYAARDLTLKAGARTLLAAFTQVFRPGEIWCVAGPNGAGKTTLLATLAGLRPPAGGDVEIDGRPLSAW
PPAQLAQRRALMPQQLHDAFSATVFDTVLLNRFPYLGGWGWERDGDREAARAALATFGLGALAGRDVLSLSGGERQRVAL
AATLCQDAPLMLLDEPLAHLDLHHQIDCLTALTDWVRARPRTVLFSCHDLNLARRFATHALLLDGRGQAWSGPVCDVLTP
ERASDAFGYPLVLIRENGRDALLPAWPERRA
>Mature_270_residues
TAARFDAAEQGAYAARDLTLKAGARTLLAAFTQVFRPGEIWCVAGPNGAGKTTLLATLAGLRPPAGGDVEIDGRPLSAWP
PAQLAQRRALMPQQLHDAFSATVFDTVLLNRFPYLGGWGWERDGDREAARAALATFGLGALAGRDVLSLSGGERQRVALA
ATLCQDAPLMLLDEPLAHLDLHHQIDCLTALTDWVRARPRTVLFSCHDLNLARRFATHALLLDGRGQAWSGPVCDVLTPE
RASDAFGYPLVLIRENGRDALLPAWPERRA

Specific function: Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI73747915, Length=213, Percent_Identity=30.0469483568075, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI46592915, Length=225, Percent_Identity=30.2222222222222, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI46592898, Length=225, Percent_Identity=30.2222222222222, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI46592971, Length=227, Percent_Identity=30.8370044052863, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI46592956, Length=225, Percent_Identity=30.2222222222222, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI46592978, Length=227, Percent_Identity=30.8370044052863, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI46592964, Length=224, Percent_Identity=29.4642857142857, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI9665248, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI11967969, Length=202, Percent_Identity=29.7029702970297, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI156105685, Length=244, Percent_Identity=30.327868852459, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI171184400, Length=227, Percent_Identity=25.5506607929515, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI73747917, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31657092, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786345, Length=238, Percent_Identity=35.7142857142857, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786803, Length=239, Percent_Identity=35.5648535564854, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790739, Length=225, Percent_Identity=34.2222222222222, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788002, Length=234, Percent_Identity=35.8974358974359, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=33.7899543378995, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=33.8541666666667, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787712, Length=204, Percent_Identity=31.3725490196078, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788225, Length=221, Percent_Identity=28.9592760180996, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786872, Length=186, Percent_Identity=30.6451612903226, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787112, Length=223, Percent_Identity=30.9417040358744, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789032, Length=236, Percent_Identity=29.2372881355932, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787143, Length=194, Percent_Identity=28.3505154639175, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081709, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=31.924882629108, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787029, Length=205, Percent_Identity=28.2926829268293, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788165, Length=238, Percent_Identity=30.2521008403361, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790467, Length=191, Percent_Identity=29.8429319371728, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082267, Length=210, Percent_Identity=29.0476190476191, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790544, Length=225, Percent_Identity=28.8888888888889, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786703, Length=199, Percent_Identity=32.1608040201005, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786398, Length=216, Percent_Identity=27.7777777777778, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788210, Length=173, Percent_Identity=30.635838150289, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788450, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789751, Length=214, Percent_Identity=29.9065420560748, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789593, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789962, Length=190, Percent_Identity=25.7894736842105, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082268, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081782, Length=235, Percent_Identity=27.6595744680851, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=29.1079812206573, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788540, Length=179, Percent_Identity=29.0502793296089, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=184, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17511077, Length=195, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=193, Percent_Identity=29.5336787564767, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=174, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397593, Length=205, Percent_Identity=29.7560975609756, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.34 [H]

Molecular weight: Translated: 29276; Mature: 29145

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTAARFDAAEQGAYAARDLTLKAGARTLLAAFTQVFRPGEIWCVAGPNGAGKTTLLATLA
CCCCCCCCHHCCCHHHHHEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
GLRPPAGGDVEIDGRPLSAWPPAQLAQRRALMPQQLHDAFSATVFDTVLLNRFPYLGGWG
HCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WERDGDREAARAALATFGLGALAGRDVLSLSGGERQRVALAATLCQDAPLMLLDEPLAHL
CCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHH
DLHHQIDCLTALTDWVRARPRTVLFSCHDLNLARRFATHALLLDGRGQAWSGPVCDVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCC
ERASDAFGYPLVLIRENGRDALLPAWPERRA
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAARFDAAEQGAYAARDLTLKAGARTLLAAFTQVFRPGEIWCVAGPNGAGKTTLLATLA
CCCCCCCHHCCCHHHHHEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
GLRPPAGGDVEIDGRPLSAWPPAQLAQRRALMPQQLHDAFSATVFDTVLLNRFPYLGGWG
HCCCCCCCCEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WERDGDREAARAALATFGLGALAGRDVLSLSGGERQRVALAATLCQDAPLMLLDEPLAHL
CCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCEEEECCCHHHH
DLHHQIDCLTALTDWVRARPRTVLFSCHDLNLARRFATHALLLDGRGQAWSGPVCDVLTP
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCC
ERASDAFGYPLVLIRENGRDALLPAWPERRA
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3301821; 2823072; 8202364; 9278503 [H]