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The map label for this gene is btuC [H]

Identifier: 161524018

GI number: 161524018

Start: 915331

End: 916683

Strand: Direct

Name: btuC [H]

Synonym: Bmul_0839

Alternate gene names: 161524018

Gene position: 915331-916683 (Clockwise)

Preceding gene: 161524013

Following gene: 161524019

Centisome position: 26.54

GC content: 74.72

Gene sequence:

>1353_bases
ATGCGTGCGGCCCGGGCGCCATGGTGCGCGTCGCCCTGCGCGCGGCGGCCGCTCGCGTGCAGCGGCGCCGCAGCATCGAC
CTTGGCTCGCGCATGCGGCCACATGCTCGACCTCCGGCCGACGTCCGCACGGCAGCGTCGATGCCGGCGCTTTCCTCTAT
ATTGCGCAGATCGTGCGCGGCCGCCGCGCCGCGCACCTCGCTTCGCCAACCCGCCCGACAAGGACGATTCGTTTGCCGAT
CATCGTGACTTCCCGCGCCGCTGCGCCCGTGCCGGCTGCGGCCATCGCGCGCATTCGCGTGCACACGCAACGCGCGGCAT
GCCGTTCGCGGTGCCCCGCATGAGCGCGCGTCGCGCCGCCGCGATCTGGGCCGCGCTCGCGGTCGCGGCCGCGCTGCTGC
TCGTCGCGTCGCTGTCGATCGGCAGCGTGCCGATGTCGCCGTGGCAGGCGCTCGCGGCACTCGTGCCGCACGGCAGCGAC
GCGACGGGCGATACCGCGCTGTTCGCCGACATCGTGCGCACGCTGCGGCTCCCGCGTGCGTTGGCCGGCTTCGCATGCGG
CGCGTTGCTCGCGCTCGCCGGCGCGCTGCTGCAGGTGCTGCTGCGCAATCCGCTCGCGGAGCCGTACGTGCTCGGCGTGT
CGGGCGGCGCGGCCGGCTTCGCGCTCGTCGCGATGATTGCCGGCGGCGCGTGGTGGCTCGTCGATGCATCGGCGTTCGCC
GGTGCGCTCGTGTCGATCGCGCTCGTGCTCGGGCTCGCGCGTCGCGAACTGTGGCGCGGCGAATCGCGCGACGCATCGCC
GCGGCTGCTGCTGACCGGCGTCGTGATCGCCGCCGGCTGGGGCGCGCTCGTCACGCTGCTGCTCTCGATCGCGCCCGATG
CGCGGCTGCGCGGCATCCTGTTCTGGCTGACCGGCGATCTCAACGGCGCGAGCGCGCCGTGGTTCGCCTGGGGTGCGCTG
CTGCTCGCGGCGGCCGTCGCGCTGCCGGCCGCGCCGCAGCTGAATGTGCTGCTGCGCGGCGACGCGGCGGCGCTCGCGCT
CGGCGTGCCAGTCGCGCGGCTGCGCGTGCGCGTCTATCTCGCCGCATCGCTCGCCGCCGCGGCCGCGGTCACGACGGCCG
GCACGATCGGCTTCGTCGGCCTCGTCGTGCCGCACGCGCTGCGGCTCGCGTTCGGCAACGATCAGCGCATGCTGTTGCCC
GCCGCGATGCTCGCGGGCGGCAGCGGCGTGATGGCGGCCGACCTGCTCGCGCGCAGCGCGATCGCGCCCGCGCAATTGCC
GGTCGGCGTGATGACCGCGCTGATCGGCGTGCCGGTGTTCCTGTGGATGTTGCTGAGGAGGCCGACACGATGA

Upstream 100 bases:

>100_bases
CAATCGTCCGCCTGGCGCCGCGTGCCGCGTGCGGCTTCGCCGTTCGCTGCAGCGGCGTTCGTGCTCGCGCTCGCGTCTGC
GTTTGCGCCGGTGCACGTGC

Downstream 100 bases:

>100_bases
CCGCGGCCAGGTTCGATGCCGCAGAACAAGGCGCCTACGCAGCACGCGACCTGACGCTGAAGGCCGGCGCACGCACGCTG
CTGGCGGCATTCACGCAGGT

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRAARAPWCASPCARRPLACSGAAASTLARACGHMLDLRPTSARQRRCRRFPLYCADRARPPRRAPRFANPPDKDDSFAD
HRDFPRRCARAGCGHRAHSRAHATRGMPFAVPRMSARRAAAIWAALAVAAALLLVASLSIGSVPMSPWQALAALVPHGSD
ATGDTALFADIVRTLRLPRALAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFA
GALVSIALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSIAPDARLRGILFWLTGDLNGASAPWFAWGAL
LLAAAVALPAAPQLNVLLRGDAAALALGVPVARLRVRVYLAASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLP
AAMLAGGSGVMAADLLARSAIAPAQLPVGVMTALIGVPVFLWMLLRRPTR

Sequences:

>Translated_450_residues
MRAARAPWCASPCARRPLACSGAAASTLARACGHMLDLRPTSARQRRCRRFPLYCADRARPPRRAPRFANPPDKDDSFAD
HRDFPRRCARAGCGHRAHSRAHATRGMPFAVPRMSARRAAAIWAALAVAAALLLVASLSIGSVPMSPWQALAALVPHGSD
ATGDTALFADIVRTLRLPRALAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFA
GALVSIALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSIAPDARLRGILFWLTGDLNGASAPWFAWGAL
LLAAAVALPAAPQLNVLLRGDAAALALGVPVARLRVRVYLAASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLP
AAMLAGGSGVMAADLLARSAIAPAQLPVGVMTALIGVPVFLWMLLRRPTR
>Mature_450_residues
MRAARAPWCASPCARRPLACSGAAASTLARACGHMLDLRPTSARQRRCRRFPLYCADRARPPRRAPRFANPPDKDDSFAD
HRDFPRRCARAGCGHRAHSRAHATRGMPFAVPRMSARRAAAIWAALAVAAALLLVASLSIGSVPMSPWQALAALVPHGSD
ATGDTALFADIVRTLRLPRALAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFA
GALVSIALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSIAPDARLRGILFWLTGDLNGASAPWFAWGAL
LLAAAVALPAAPQLNVLLRGDAAALALGVPVARLRVRVYLAASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLP
AAMLAGGSGVMAADLLARSAIAPAQLPVGVMTALIGVPVFLWMLLRRPTR

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=39.1459074733096, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790741, Length=340, Percent_Identity=36.1764705882353, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790740, Length=334, Percent_Identity=35.6287425149701, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=38.6759581881533, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786347, Length=304, Percent_Identity=31.25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786804, Length=319, Percent_Identity=36.9905956112853, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 46802; Mature: 46802

Theoretical pI: Translated: 12.13; Mature: 12.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARAPWCASPCARRPLACSGAAASTLARACGHMLDLRPTSARQRRCRRFPLYCADRAR
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCC
PPRRAPRFANPPDKDDSFADHRDFPRRCARAGCGHRAHSRAHATRGMPFAVPRMSARRAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
AIWAALAVAAALLLVASLSIGSVPMSPWQALAALVPHGSDATGDTALFADIVRTLRLPRA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEHHHHH
GALVSIALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSIAPDARLRGIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEE
FWLTGDLNGASAPWFAWGALLLAAAVALPAAPQLNVLLRGDAAALALGVPVARLRVRVYL
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHH
AASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGSGVMAADLLARSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHC
IAPAQLPVGVMTALIGVPVFLWMLLRRPTR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAARAPWCASPCARRPLACSGAAASTLARACGHMLDLRPTSARQRRCRRFPLYCADRAR
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCC
PPRRAPRFANPPDKDDSFADHRDFPRRCARAGCGHRAHSRAHATRGMPFAVPRMSARRAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
AIWAALAVAAALLLVASLSIGSVPMSPWQALAALVPHGSDATGDTALFADIVRTLRLPRA
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAGFACGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALVAMIAGGAWWLVDASAFA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEHHHHH
GALVSIALVLGLARRELWRGESRDASPRLLLTGVVIAAGWGALVTLLLSIAPDARLRGIL
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEEE
FWLTGDLNGASAPWFAWGALLLAAAVALPAAPQLNVLLRGDAAALALGVPVARLRVRVYL
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHCCHHHHHHHHHHH
AASLAAAAAVTTAGTIGFVGLVVPHALRLAFGNDQRMLLPAAMLAGGSGVMAADLLARSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHC
IAPAQLPVGVMTALIGVPVFLWMLLRRPTR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA