| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is phbB [H]
Identifier: 161523724
GI number: 161523724
Start: 594766
End: 595509
Strand: Direct
Name: phbB [H]
Synonym: Bmul_0544
Alternate gene names: 161523724
Gene position: 594766-595509 (Clockwise)
Preceding gene: 161523723
Following gene: 161523725
Centisome position: 17.25
GC content: 63.84
Gene sequence:
>744_bases ATGACTAAGCGAATTGCAGTTGTGACAGGTGGGATGGGCGGTCTCGGTGAGGCGATCAGCATCAGGTTGCACGAAGCGGG CCACCGGGTTGTCGTCACGTATTCGCCGAACAACACGGGCGCGGATCGCTGGCTGACCGAAATGCAGGCGGCCGGCCGCC AGTTCGACGCCTATCCCGTCGACGTGGCCGATCACGACTCGTGCCAGCAGTGCGTCGAGAAGATCGTGCGCGACGTCGGC CCGATCGACATCCTGGTGAACAACGCGGGCATCACGCGCGACATGACGCTGCGCAAGCTCGACAAGGTCAACTGGGACGC GGTGATCCGCACGAACCTCGACTCGGTGTTCAACATGACGAAGCCGATCTGCGAAGGGATGATCGAGCGCGGCTGGGGAC GCATCGTCAACATCTCGTCCGTCAACGGTTCGAAGGGATCGGTCGGCCAGACCAACTATGCGGCCGCGAAAGCCGGCATG CACGGCTTCACGAAGTCGCTCGCGCTCGAAGTCGCGCGCAAGGGCGTGACCGTCAACACGGTCTCGCCCGGCTATCTCGC GACGAAGATGGTGATGGCTATCCCGCAGGACATCCTCGACACGAAGGTGCTCCCGCAGATTCCGGCCGGGCGGCTCGGCA AGCCCGAGGAAGTCGCGGCGCTCGTCGCGTATCTGTGCTCGGAGGAAGCGGGCTTCGTGACGGGGTCGAACATCGCGATC AACGGCGGCCAGCACATGCACTGA
Upstream 100 bases:
>100_bases CCCGATCATCGGGCGGCGGCGTGCCGAGGCGGCGGGCGGCGGCGTGTGCCACGTCGCGGTCCCGCCTCATCGATTACTTT TTTTGTTGGTGAATAATAGG
Downstream 100 bases:
>100_bases CGGCCGACGGCCCGCTCCGCGCGGGCCGTGTTCGTGCTGCATCCCGTGCCGGCGCCGTTCATCGGCGCCGGCGTCGTGTT CCGGAGGACGCATGGGTGAA
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 247; Mature: 246
Protein sequence:
>247_residues MTKRIAVVTGGMGGLGEAISIRLHEAGHRVVVTYSPNNTGADRWLTEMQAAGRQFDAYPVDVADHDSCQQCVEKIVRDVG PIDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPICEGMIERGWGRIVNISSVNGSKGSVGQTNYAAAKAGM HGFTKSLALEVARKGVTVNTVSPGYLATKMVMAIPQDILDTKVLPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAI NGGQHMH
Sequences:
>Translated_247_residues MTKRIAVVTGGMGGLGEAISIRLHEAGHRVVVTYSPNNTGADRWLTEMQAAGRQFDAYPVDVADHDSCQQCVEKIVRDVG PIDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPICEGMIERGWGRIVNISSVNGSKGSVGQTNYAAAKAGM HGFTKSLALEVARKGVTVNTVSPGYLATKMVMAIPQDILDTKVLPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAI NGGQHMH >Mature_246_residues TKRIAVVTGGMGGLGEAISIRLHEAGHRVVVTYSPNNTGADRWLTEMQAAGRQFDAYPVDVADHDSCQQCVEKIVRDVGP IDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPICEGMIERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMH GFTKSLALEVARKGVTVNTVSPGYLATKMVMAIPQDILDTKVLPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAIN GGQHMH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=36.2549800796813, Blast_Score=157, Evalue=7e-39, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=1e-29, Organism=Homo sapiens, GI4504505, Length=239, Percent_Identity=34.3096234309623, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=30.2040816326531, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=4e-26, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI66933014, Length=200, Percent_Identity=30.5, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=26.8, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=30.241935483871, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI4503301, Length=198, Percent_Identity=29.7979797979798, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=31.0880829015544, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=30, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=29.5, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=30.8457711442786, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI7705855, Length=191, Percent_Identity=32.4607329842932, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=29.1208791208791, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=27.2321428571429, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI226371731, Length=201, Percent_Identity=31.8407960199005, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=44.4444444444444, Blast_Score=199, Evalue=1e-52, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=35.15625, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=33.1967213114754, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=31.9502074688797, Blast_Score=134, Evalue=5e-33, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=30.2904564315353, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=29.8755186721992, Blast_Score=125, Evalue=4e-30, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.8775510204082, Blast_Score=114, Evalue=4e-27, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=34.4262295081967, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=28.6290322580645, Blast_Score=100, Evalue=6e-23, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=27.8688524590164, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.843137254902, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=30.5343511450382, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=30.939226519337, Blast_Score=82, Evalue=5e-17, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=41.6326530612245, Blast_Score=173, Evalue=9e-44, Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=38.0952380952381, Blast_Score=158, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17568967, Length=246, Percent_Identity=34.1463414634146, Blast_Score=124, Evalue=6e-29, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=31.5789473684211, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.8, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=30.4182509505703, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=30.5882352941176, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=34.3915343915344, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=33.8541666666667, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=28.740157480315, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=27.6264591439689, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.8039215686275, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=29.6875, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=27.6515151515151, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=26.615969581749, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.3076923076923, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=26.4925373134328, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=27.3764258555133, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=26.2172284644195, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=29.5719844357977, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.4354838709677, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.5590551181102, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=187, Percent_Identity=29.9465240641711, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=27.9693486590038, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=28.0769230769231, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17561272, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=26.0204081632653, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193207185, Length=146, Percent_Identity=30.1369863013699, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=237, Percent_Identity=31.2236286919831, Blast_Score=111, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=27.2, Blast_Score=78, Evalue=1e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=8e-13, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=36.4754098360656, Blast_Score=140, Evalue=8e-34, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=35.0393700787402, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI18859837, Length=236, Percent_Identity=35.5932203389831, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.5785123966942, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=31.4516129032258, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=29.6, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=9e-22, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=28.90625, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21358495, Length=202, Percent_Identity=30.1980198019802, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24644337, Length=175, Percent_Identity=35.4285714285714, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=31.3829787234043, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=31.3609467455621, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=32.5, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=32.5, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.7708333333333, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.7708333333333, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581726, Length=158, Percent_Identity=29.1139240506329, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=32.3383084577114, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=32.3383084577114, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26447; Mature: 26316
Theoretical pI: Translated: 7.99; Mature: 7.99
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 4.0 %Met (Translated Protein) 5.7 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 5.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTKRIAVVTGGMGGLGEAISIRLHEAGHRVVVTYSPNNTGADRWLTEMQAAGRQFDAYPV CCCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC DVADHDSCQQCVEKIVRDVGPIDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHH KPICEGMIERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEVARKGVTVNT HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE VSPGYLATKMVMAIPQDILDTKVLPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAI CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEE NGGQHMH CCCCCCC >Mature Secondary Structure TKRIAVVTGGMGGLGEAISIRLHEAGHRVVVTYSPNNTGADRWLTEMQAAGRQFDAYPV CCEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC DVADHDSCQQCVEKIVRDVGPIDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCHHHHHHHH KPICEGMIERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEVARKGVTVNT HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE VSPGYLATKMVMAIPQDILDTKVLPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSNIAI CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEE NGGQHMH CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2670935 [H]