Click here to switch to the map view.

The map label for this gene is leuE [H]

Identifier: 161523712

GI number: 161523712

Start: 580360

End: 580974

Strand: Direct

Name: leuE [H]

Synonym: Bmul_0532

Alternate gene names: 161523712

Gene position: 580360-580974 (Clockwise)

Preceding gene: 161523711

Following gene: 161523713

Centisome position: 16.83

GC content: 68.94

Gene sequence:

>615_bases
ATGCCGAACTTCATGCTGTTTCTCGCCACGTCGATCGCGATCACGTTCGCGCCGGGTCCCGACAACCTGCAGGTGCTCGC
GCGCGGCATCTCGCAGGGCCGCGCGGCCGGCTTCGTCGCCGCGCTCGGCTTCACGGCCGGCATCCTGTTCCACACGACGC
TCGCGGCGCTCGGCGTCGCGGCCGTGCTGCGTTCGTCGCCGCTCGCGTTTCAGATCCTGAAGCTCGCGGGCGCCGCGTAT
CTCGTCTGGATCGGCATCAAGGCGTTGCGCAGCCACGGCCTCGCGAATGCGCATGCGCGGCCGCCGCAGCCGCTCGGCGC
GATTTTCCGGCAGAGCGTGATCGGCAACCTGATGAACCCGAAGGTCACGCTGTTCTTCGTGGTGTTCCTGCCGCAGTTCG
TCGATCCGCACGGCGCGCAGAGCGTGACGCTGCAGATGTTCGAACTCGGCGCGCTGTTCATGCTGCAGACGGCCGCGATC
TTCTCGCTGTTCGGCGTCGGCGCGGGCGCGATCGGCGCGTGGCTGAAGCGCCGTCCGAAGGCCGGCGTCTGGCTCGACCG
TCTGGCCGGCGCGACGTTCATCGCGATCGGCATCCGCGTGGCGCTGAAGGACTGA

Upstream 100 bases:

>100_bases
ATCTCGGCGGCTCGGCGCTGCTGCGCAATGCGGGGCTGCCCGTCTATACCGTCACCGAATTCGCCGGCCACTGAGCGCCG
GTTCACGCAGCGAGGCCACG

Downstream 100 bases:

>100_bases
CGACGATGACTTTTCCGTGCATCGCGGCCGCGCGCCGCTTCGACCCGTCCGCGCACGTGCGCTTCGAAATCGCCGGGGCG
GCGGTCGGCTGGATTCGTCG

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MPNFMLFLATSIAITFAPGPDNLQVLARGISQGRAAGFVAALGFTAGILFHTTLAALGVAAVLRSSPLAFQILKLAGAAY
LVWIGIKALRSHGLANAHARPPQPLGAIFRQSVIGNLMNPKVTLFFVVFLPQFVDPHGAQSVTLQMFELGALFMLQTAAI
FSLFGVGAGAIGAWLKRRPKAGVWLDRLAGATFIAIGIRVALKD

Sequences:

>Translated_204_residues
MPNFMLFLATSIAITFAPGPDNLQVLARGISQGRAAGFVAALGFTAGILFHTTLAALGVAAVLRSSPLAFQILKLAGAAY
LVWIGIKALRSHGLANAHARPPQPLGAIFRQSVIGNLMNPKVTLFFVVFLPQFVDPHGAQSVTLQMFELGALFMLQTAAI
FSLFGVGAGAIGAWLKRRPKAGVWLDRLAGATFIAIGIRVALKD
>Mature_203_residues
PNFMLFLATSIAITFAPGPDNLQVLARGISQGRAAGFVAALGFTAGILFHTTLAALGVAAVLRSSPLAFQILKLAGAAYL
VWIGIKALRSHGLANAHARPPQPLGAIFRQSVIGNLMNPKVTLFFVVFLPQFVDPHGAQSVTLQMFELGALFMLQTAAIF
SLFGVGAGAIGAWLKRRPKAGVWLDRLAGATFIAIGIRVALKD

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI48994979, Length=192, Percent_Identity=28.6458333333333, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI48994978, Length=208, Percent_Identity=28.8461538461538, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21521; Mature: 21390

Theoretical pI: Translated: 12.18; Mature: 12.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNFMLFLATSIAITFAPGPDNLQVLARGISQGRAAGFVAALGFTAGILFHTTLAALGVA
CCCHHEEEEHHEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLRSSPLAFQILKLAGAAYLVWIGIKALRSHGLANAHARPPQPLGAIFRQSVIGNLMNP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
KVTLFFVVFLPQFVDPHGAQSVTLQMFELGALFMLQTAAIFSLFGVGAGAIGAWLKRRPK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
AGVWLDRLAGATFIAIGIRVALKD
CCHHHHHHCCHHEEEEEEEEEECC
>Mature Secondary Structure 
PNFMLFLATSIAITFAPGPDNLQVLARGISQGRAAGFVAALGFTAGILFHTTLAALGVA
CCHHEEEEHHEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLRSSPLAFQILKLAGAAYLVWIGIKALRSHGLANAHARPPQPLGAIFRQSVIGNLMNP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
KVTLFFVVFLPQFVDPHGAQSVTLQMFELGALFMLQTAAIFSLFGVGAGAIGAWLKRRPK
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
AGVWLDRLAGATFIAIGIRVALKD
CCHHHHHHCCHHEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]