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The map label for this gene is bioC [C]

Identifier: 161523634

GI number: 161523634

Start: 497073

End: 498038

Strand: Direct

Name: bioC [C]

Synonym: Bmul_0454

Alternate gene names: 161523634

Gene position: 497073-498038 (Clockwise)

Preceding gene: 161523631

Following gene: 161523635

Centisome position: 14.41

GC content: 70.91

Gene sequence:

>966_bases
ATGTCCCCAGCTTCGACTCCAACCGGCCGTCCGGCCAATGACGCACGGCGCCTGCGGCGGATCTTCGACCGCCGTGCCGC
CGCGTTCGACGCGGTCGCGTTCCTGCCGCGCGAGATCGCGCAGCGCATGTGCGAACGCCTCGAATACATCAAGGTGAATC
CGACGGCCGTGCTCGACGCGGGCTGCGGCGCGGGCGACGACCTGCCGGCGCTGCGCGCGCGGTTCCCCGAGGCGCCGGTG
TTCGGCGTCGACCTGTCGCACGCGATGCTCGCACGCGCCGCGCAGCGCGAGCTCGAGCAGACGAGCTGGCGCCGCTGGCT
GCCTGCATCGCTCGGCCGGGCGCTCGGACAGCGCGGCCCGCGCGTCGCGCAGGCCGATTTCTCGGCGCTGCCGTTCGCGG
ACGGCGCATTCGAGCTGGTCTGGTCGAATCTCGCGCTCCACTGGCATTCGCGTCCCGACACGGTGTTCCCCGAATGGCAG
CGCGTGCTGCGCGTGAACGGCCTGCTGATGTTCAGCACGCTCGGCCCCGACACGCTGCGCGAACTGCGCGCCGCCTGCGC
GGACGCGGAAGCGGCGCTCGGCATCGCGCCGGCGGCCGCACGCGTGATCGATTTCGTCGACATGCACGATCTCGGCGACA
TGCTCGTCGAAAGCGGCTTCGAGATCCCGGTGATGGACCAGGAAGTGCTGACCGTCACGTACAAGTCTGCCGAGTCGCTG
CTCGCCGACGTGCGCCGCTGGGGCGCCTATCCGTTTGCGCGCACGGCGCCGCTGCACGCGTCGCGGCGCTTTCGCGACGC
GCTCGCGAACGCGCTGGAAGCGCGCCGCCGCGCGGACGGCACGATCCCGCTGACGTTCGAAGTGATCTACGGCCACGCCT
GGAAGGCGGTGCCGCGCACGACGCCGGAAGGGCACGGGATCGTGCGTATCGAAGACATCGGAAAGGGGCGTCCGAAGAAT
CGGTAA

Upstream 100 bases:

>100_bases
ACGGAACGGCGGACCATCGCGAACACTCCTTGCGGCCCGGCTTCGCTGAAGCGTGCAGGGCGAGCGAGTATACTTCGGGC
TCTTCGCCCGTGTGCCCGAC

Downstream 100 bases:

>100_bases
GGCGGTAAAGAGGGGTTTTGTTATGTCTGAAATTAGCGGCGCGAAGCGGGGTCGAATTGAGGCCGGAAATGGCCGGAAAG
CTTGTCGCGCTTGGCTCGCG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: Biotin Synthesis Protein BioC; Methyltransferase Type; Biotin Synthesis Protein; Methyltransferase; SAM-Dependent Methyltransferase; Biotin Synthase BioC; UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase; Biotin Synthesis Protein Bioc; BIOTIN SYNSIS METHYLTRANSFERASE BioC; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; LOW QUALITY PROTEIN Biotin Synthesis Protein; Biotin Biosynthesis Methyltransferase BioC; S-Adenosyl-L-Methionine-Dependent Methyltransferases; Biotin Biosynthesis Protein Bioc; SAM-Dependent Methyltransferase Protein; Methyltransferase Domain-Containing Protein

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSPASTPTGRPANDARRLRRIFDRRAAAFDAVAFLPREIAQRMCERLEYIKVNPTAVLDAGCGAGDDLPALRARFPEAPV
FGVDLSHAMLARAAQRELEQTSWRRWLPASLGRALGQRGPRVAQADFSALPFADGAFELVWSNLALHWHSRPDTVFPEWQ
RVLRVNGLLMFSTLGPDTLRELRAACADAEAALGIAPAAARVIDFVDMHDLGDMLVESGFEIPVMDQEVLTVTYKSAESL
LADVRRWGAYPFARTAPLHASRRFRDALANALEARRRADGTIPLTFEVIYGHAWKAVPRTTPEGHGIVRIEDIGKGRPKN
R

Sequences:

>Translated_321_residues
MSPASTPTGRPANDARRLRRIFDRRAAAFDAVAFLPREIAQRMCERLEYIKVNPTAVLDAGCGAGDDLPALRARFPEAPV
FGVDLSHAMLARAAQRELEQTSWRRWLPASLGRALGQRGPRVAQADFSALPFADGAFELVWSNLALHWHSRPDTVFPEWQ
RVLRVNGLLMFSTLGPDTLRELRAACADAEAALGIAPAAARVIDFVDMHDLGDMLVESGFEIPVMDQEVLTVTYKSAESL
LADVRRWGAYPFARTAPLHASRRFRDALANALEARRRADGTIPLTFEVIYGHAWKAVPRTTPEGHGIVRIEDIGKGRPKN
R
>Mature_320_residues
SPASTPTGRPANDARRLRRIFDRRAAAFDAVAFLPREIAQRMCERLEYIKVNPTAVLDAGCGAGDDLPALRARFPEAPVF
GVDLSHAMLARAAQRELEQTSWRRWLPASLGRALGQRGPRVAQADFSALPFADGAFELVWSNLALHWHSRPDTVFPEWQR
VLRVNGLLMFSTLGPDTLRELRAACADAEAALGIAPAAARVIDFVDMHDLGDMLVESGFEIPVMDQEVLTVTYKSAESLL
ADVRRWGAYPFARTAPLHASRRFRDALANALEARRRADGTIPLTFEVIYGHAWKAVPRTTPEGHGIVRIEDIGKGRPKNR

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=330, Percent_Identity=26.0606060606061, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI86792933, Length=183, Percent_Identity=28.4153005464481, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535003, Length=316, Percent_Identity=25.6329113924051, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19922210, Length=312, Percent_Identity=28.8461538461538, Blast_Score=98, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35553; Mature: 35422

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPASTPTGRPANDARRLRRIFDRRAAAFDAVAFLPREIAQRMCERLEYIKVNPTAVLDA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEC
GCGAGDDLPALRARFPEAPVFGVDLSHAMLARAAQRELEQTSWRRWLPASLGRALGQRGP
CCCCCCCCHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
RVAQADFSALPFADGAFELVWSNLALHWHSRPDTVFPEWQRVLRVNGLLMFSTLGPDTLR
CEECCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHH
ELRAACADAEAALGIAPAAARVIDFVDMHDLGDMLVESGFEIPVMDQEVLTVTYKSAESL
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEHHHHHHH
LADVRRWGAYPFARTAPLHASRRFRDALANALEARRRADGTIPLTFEVIYGHAWKAVPRT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHCCCCC
TPEGHGIVRIEDIGKGRPKNR
CCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
SPASTPTGRPANDARRLRRIFDRRAAAFDAVAFLPREIAQRMCERLEYIKVNPTAVLDA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEC
GCGAGDDLPALRARFPEAPVFGVDLSHAMLARAAQRELEQTSWRRWLPASLGRALGQRGP
CCCCCCCCHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
RVAQADFSALPFADGAFELVWSNLALHWHSRPDTVFPEWQRVLRVNGLLMFSTLGPDTLR
CEECCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHH
ELRAACADAEAALGIAPAAARVIDFVDMHDLGDMLVESGFEIPVMDQEVLTVTYKSAESL
HHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEHHHHHHH
LADVRRWGAYPFARTAPLHASRRFRDALANALEARRRADGTIPLTFEVIYGHAWKAVPRT
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHCCCCC
TPEGHGIVRIEDIGKGRPKNR
CCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA