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The map label for this gene is murA [H]

Identifier: 161523506

GI number: 161523506

Start: 357403

End: 358752

Strand: Direct

Name: murA [H]

Synonym: Bmul_0326

Alternate gene names: 161523506

Gene position: 357403-358752 (Clockwise)

Preceding gene: 161523505

Following gene: 161523507

Centisome position: 10.36

GC content: 68.67

Gene sequence:

>1350_bases
GTGCAAGTCACCGTCAACGAGCGCGACGCCGTGCAGAGCGTCGCGACGGCACACCCGGCCGCCAACGGGGAAACGCAGGG
GCAGGGGATGGACAAGCTCGTGATCGAAGGCGGCCGCCGGCTCGCGGGCGAGATCGTCGTGTCGGGCGCGAAGAATGCGG
CGCTGCCGATTCTGTGCGCGGGGCTGCTGAGCGCCGAGCCCGTGCACCTCGACAACGTGCCGAATCTGCAGGACGTACGC
ACCACGCTGAAGGTGCTCGGCCAGATGGGCGTGAAGAGCGAGACCGACGGCTGCCGCGTGCAGCTCGACGCGTCGCGCGT
CGACAACCTCGTCGCGCCGTACGAGCTCGTGAAGACGATGCGCGCGTCGATCCTCGTGCTCGGCCCGCTGCTCGCGCGCT
TCGGCGAGGCGAAGGTATCGCTGCCCGGCGGCTGCGCGATCGGTGCGCGGCCCGTCGACCAGCACATCAAGGGGCTGCAG
GCGATGGGCGCCGAGATCAGCATCGAGCACGGCTTCATCGAGGCGCGCGCGAAGCGTCTGAAGGGCGCGCGCATCGTGAC
CGACATGATCACCGTGACGGGCACCGAAAACCTGCTGATGGCCGCCACGCTCGCCGACGGCGAGACCGTGATCGAAAACG
CGGCGCGCGAACCGGAAGTGAGCGATCTCGCACACTTGCTGGTCGCGATGGGCGCGAAAATCGACGGCATCGGCACCGAC
CGCCTCGTGATCCAGGGCGTCGAGCGCCTGCACGGCGCGCACCACGCGGTGATTCCGGACCGCATCGAGGCCGGCACGTT
CCTGTGCGCGGTCGCGGCGGCGGGCGGCGACGTGACGCTGACCGGCGTGCGTCCGCACATCCTCGACGCGGTGATCGACA
AGCTCCGTGAAGCCGGCGTGACGGTCGAGGAAGGCGATCGCTGGCTGCGCGTGAAGATGGATCGCCGGCCGAACGCGGTG
ACGATCCGCACGTCCGAATACCCGGCGTTTCCGACCGACATGCAGGCACAGTTCATGGCGCTCAATTCGGTGGCGACCGG
TACCGCGCAGGTCGTCGAAACGATCTTCGAGAACCGCTTCATGCACGTGCAGGAGCTGAACCGCCTCGGCGCGAACATCA
CGGTCGACGGCAATACGGCGCTCGTGACCGGCGTTGACAAGCTGTCGGGCGCGAACGTGATGGCGACCGATCTGCGCGCG
TCCGCGAGCCTCGTGATCGCCGGGCTGCGCGCCGAAGGCGAGACGCGCGTCGACCGCATCTATCACCTCGATCGCGGCTA
CGACCGCATGGAAGCCAAACTGACCGCCGTCGGCGCGAACGTGCGCCGCGTCTCCGGGAGCCAAGCATGA

Upstream 100 bases:

>100_bases
TATGCGGCGCTCGGCGACCGCATGAAGCAGGAAATCCACGCGCTCAGCATGAAGACGCTGACGCCCGCCGAATGGCAGAA
CGCATAACCGGAAAAACTGA

Downstream 100 bases:

>100_bases
CCGCGCCGCTGACCCTCGCCCTGTCGAAGGGCCGCATTTTCGAGGAAACCCTGCCGCTGCTGGCCGCCGCCGGCGTGCAG
GTCGCCGAGGATCCGGAAAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQVTVNERDAVQSVATAHPAANGETQGQGMDKLVIEGGRRLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPNLQDVR
TTLKVLGQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGAHHAVIPDRIEAGTFLCAVAAAGGDVTLTGVRPHILDAVIDKLREAGVTVEEGDRWLRVKMDRRPNAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQVVETIFENRFMHVQELNRLGANITVDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETRVDRIYHLDRGYDRMEAKLTAVGANVRRVSGSQA

Sequences:

>Translated_449_residues
MQVTVNERDAVQSVATAHPAANGETQGQGMDKLVIEGGRRLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPNLQDVR
TTLKVLGQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGAHHAVIPDRIEAGTFLCAVAAAGGDVTLTGVRPHILDAVIDKLREAGVTVEEGDRWLRVKMDRRPNAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQVVETIFENRFMHVQELNRLGANITVDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETRVDRIYHLDRGYDRMEAKLTAVGANVRRVSGSQA
>Mature_449_residues
MQVTVNERDAVQSVATAHPAANGETQGQGMDKLVIEGGRRLAGEIVVSGAKNAALPILCAGLLSAEPVHLDNVPNLQDVR
TTLKVLGQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGAHHAVIPDRIEAGTFLCAVAAAGGDVTLTGVRPHILDAVIDKLREAGVTVEEGDRWLRVKMDRRPNAV
TIRTSEYPAFPTDMQAQFMALNSVATGTAQVVETIFENRFMHVQELNRLGANITVDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRAEGETRVDRIYHLDRGYDRMEAKLTAVGANVRRVSGSQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=58.7112171837709, Blast_Score=493, Evalue=1e-141,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47651; Mature: 47651

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTVNERDAVQSVATAHPAANGETQGQGMDKLVIEGGRRLAGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEECEEEEECCCCCCHHHHHH
GLLSAEPVHLDNVPNLQDVRTTLKVLGQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
CCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGAHHAVIPDRIEAGTFLCAVAAAGGDVTLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
TVEEGDRWLRVKMDRRPNAVTIRTSEYPAFPTDMQAQFMALNSVATGTAQVVETIFENRF
EEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVQELNRLGANITVDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETRVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEEHHHCCCEEEEEEECCCCCHHHHHH
YHLDRGYDRMEAKLTAVGANVRRVSGSQA
HHHCCCCHHHHHHHHEECCCCEECCCCCC
>Mature Secondary Structure
MQVTVNERDAVQSVATAHPAANGETQGQGMDKLVIEGGRRLAGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEECEEEEECCCCCCHHHHHH
GLLSAEPVHLDNVPNLQDVRTTLKVLGQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
CCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGAHHAVIPDRIEAGTFLCAVAAAGGDVTLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
TVEEGDRWLRVKMDRRPNAVTIRTSEYPAFPTDMQAQFMALNSVATGTAQVVETIFENRF
EEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
MHVQELNRLGANITVDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRAEGETRVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEEHHHCCCEEEEEEECCCCCHHHHHH
YHLDRGYDRMEAKLTAVGANVRRVSGSQA
HHHCCCCHHHHHHHHEECCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA