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The map label for this gene is mmlH [H]

Identifier: 161523490

GI number: 161523490

Start: 342958

End: 344220

Strand: Reverse

Name: mmlH [H]

Synonym: Bmul_0310

Alternate gene names: 161523490

Gene position: 344220-342958 (Counterclockwise)

Preceding gene: 161523491

Following gene: 161523489

Centisome position: 9.98

GC content: 66.98

Gene sequence:

>1263_bases
ATGCAGGCAATCCAGTGGTTTCGAGAACTGTCGTCGCGCGAGCGCCGCACGCTGTATGCGGGCTTCGGCGGCTATGCAGT
CGACGCGTTCGACTTCATGATCTACTCGTTCCTGATTCCGACGCTGATCGCGACCTGGGGCATGACGAAGAGCGAGGCCG
GCATGATCGCGACGAGCTCGCTGATCTCGTCCGCGATCGGCGGCTGGGTCGCCGGCATCCTCGCCGACCGCTACGGCCGC
GTGCGCGTGCTGCAGTGGACGATCGCGACGTTCGCGCTGTTCACGTGCCTGTCCGGCTTCACGCACTCGTTCTGGCAGCT
GCTCGCGACGCGCACGCTGCAGGGCTTCGGCTTCGGCGGCGAGTGGTCGGTCGTGACGATCATGATGGCCGAAACGATCC
GCTCGCCCGAGCATCGCGCGAAGGCGGTCGGCACCGTGCAGAGCAGCTGGTCGTTCGGCTGGGCCGCGGCCGCGATTCTC
TACTGGGCCTTCTTCGCGCTGCTGCCGGAGCAGGTCGCGTGGCGCGCGTGCTTCTGGATCGGCATCGCGCCCGCGCTGTG
GATCCTGTATATCCGCCGCAACGTCAGCGATCCCGACATCTACACGGCCACGCGCCGAGCGCGCGACGAAGGCCGCGTGT
CGGGCCACTTCCTCGAGATCTTCTCGCCGCCGCATCTGCGCGCGACGCTGTTCGGCAGCGCACTGTGCACCGGCATGCTC
GGCGGCTACTACGCGATCACGACCTGGCTGCCCACCTATCTGAAAACCGTCCGGCACCTGTCCGTCTTCAACACGAGCGG
CTATCTGGTCGTGCTGATCGTCGGATCGTTCGTCGGCTACGTGGTCGGCGCGATCCTGTCCGACCGGCTCGGCCGCCGCG
CCTCGTTCATCCTGTTCGCGATCGGATCCTTCACGCTCGGGATGGCCTATACGATGCTGCCGATCACCGACACCGCGATG
CTCGCGCTCGGCTTTCCGCTCGGCATCGTCGTGCAGGGCATCTTCGCGGGCGTCGGCGCGTATCTGTCCGAACTCTATCC
GGGTGCGATCCGCGGCTCGGGCCAGGGCTTCTGCTACAACCTCGGCCGCGGGCTCGGCTCGTTCTTTCCGATCCTCGTCG
GCTCGCTGTCGCAGTCGATGTCGCTCGTGAAGGCGATCGGATTCGTCGCCGGCGGCGGCTATCTGCTCGTGATCGTCGCC
GCGCTCGTGCTGCCGGAAACGCGCGGCAAGTCGCTGGCCGACGATCCGGCCGTCGCATCGTGA

Upstream 100 bases:

>100_bases
ATCGCACCGCCTCGCGTCAGCCTTTTTGGCGCGCACGATCCCGCCCGTACAATAGCCGCCACACGGCACCACGATGACGA
ACGGGACGGGAGACAGCGGC

Downstream 100 bases:

>100_bases
ACCGCCGTTTCGCTCCGGGTACCGCATGCATGTGATCGTCCTCGGCGCCGGCGTGATCGGCGTCGCTACCGCGTGGCACC
TGCGCGAAGCGGGCTGCGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MQAIQWFRELSSRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWAAAAIL
YWAFFALLPEQVAWRACFWIGIAPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFTLGMAYTMLPITDTAM
LALGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGFVAGGGYLLVIVA
ALVLPETRGKSLADDPAVAS

Sequences:

>Translated_420_residues
MQAIQWFRELSSRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWAAAAIL
YWAFFALLPEQVAWRACFWIGIAPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFTLGMAYTMLPITDTAM
LALGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGFVAGGGYLLVIVA
ALVLPETRGKSLADDPAVAS
>Mature_420_residues
MQAIQWFRELSSRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSSLISSAIGGWVAGILADRYGR
VRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGGEWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWAAAAIL
YWAFFALLPEQVAWRACFWIGIAPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFAIGSFTLGMAYTMLPITDTAM
LALGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYNLGRGLGSFFPILVGSLSQSMSLVKAIGFVAGGGYLLVIVA
ALVLPETRGKSLADDPAVAS

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=378, Percent_Identity=27.5132275132275, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082231, Length=439, Percent_Identity=25.2847380410023, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790550, Length=437, Percent_Identity=25.1716247139588, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082159, Length=365, Percent_Identity=27.3972602739726, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081723, Length=337, Percent_Identity=25.5192878338279, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788942, Length=387, Percent_Identity=25.0645994832041, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=443, Percent_Identity=24.6049661399549, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45582; Mature: 45582

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIQWFRELSSRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSAIGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWAAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IGSFTLGMAYTMLPITDTAMLALGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
HHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGSLSQSMSLVKAIGFVAGGGYLLVIVAALVLPETRGKSLADDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQAIQWFRELSSRERRTLYAGFGGYAVDAFDFMIYSFLIPTLIATWGMTKSEAGMIATSS
CCHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LISSAIGGWVAGILADRYGRVRVLQWTIATFALFTCLSGFTHSFWQLLATRTLQGFGFGG
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EWSVVTIMMAETIRSPEHRAKAVGTVQSSWSFGWAAAAILYWAFFALLPEQVAWRACFWI
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAPALWILYIRRNVSDPDIYTATRRARDEGRVSGHFLEIFSPPHLRATLFGSALCTGML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
GGYYAITTWLPTYLKTVRHLSVFNTSGYLVVLIVGSFVGYVVGAILSDRLGRRASFILFA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IGSFTLGMAYTMLPITDTAMLALGFPLGIVVQGIFAGVGAYLSELYPGAIRGSGQGFCYN
HHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGRGLGSFFPILVGSLSQSMSLVKAIGFVAGGGYLLVIVAALVLPETRGKSLADDPAVAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]