Click here to switch to the map view.

The map label for this gene is gltA [H]

Identifier: 161511190

GI number: 161511190

Start: 2591718

End: 2593022

Strand: Reverse

Name: gltA [H]

Synonym: BT_2070

Alternate gene names: 161511190

Gene position: 2593022-2591718 (Counterclockwise)

Preceding gene: 29347481

Following gene: 29347478

Centisome position: 41.42

GC content: 48.43

Gene sequence:

>1305_bases
ATGAAAGAGGCAACCCGGATTGACAATGAATTGTTCCCCAAGTTTGACGTGAAGCGTGGACTGCGTAATGAAGACGGCAC
CGGTGTATTGGTAGGTCTGACAAAGATTGGTAATGTGGTAGGTTACGAACGTATCCCCGGCGGCGGTCTGAAGCCAATTC
CGGGAAAATTGTTCTATCGGGGCTACGATGTGGAAGACATTTCCCACGCCATCATCAAGGAAAAACGTTTCGGCTTCGAA
GAAGTGGCTTATCTGCTGCTTTCCGGTCGCCTGCCGGACAAGGAAGAACTGGCTTCTTTCCGCGAACTGATCAATGACAA
TATGGCGCTCGAACAGAAGACGAAAATGAATATTATCGAGCTGGAGGGAAATAATATCATGAATATTCTTTCGCGCAGCG
TACTCGAAATGTATCGTTTCGATCCCGATGCCGACGATACTTCCCGCGATAATCTGATGCGCCAGAGTATCGATCTTATC
TCCAAGTTCCCGACCATCATTGCGTATGCTTATAATATGCTCCGCCATGCTACATTCGGTCGTTCCCTGCACATCCGTCA
TCCGCAGGAGAAACTCTCTATTGCCGAGAATTTCCTCTATATGCTCAAAAAAGATTATACGGAACTGGATGCCCGTACGC
TCGACTTGCTATTGATTTTGCAGGCAGAACACGGCGGTGGTAACAACTCGACTTTCACGGTTCGTGTGACTTCTTCCACC
GGAACAGATACATATTCGGCCATCGCCGCAGGTATCGGTTCGTTGAAAGGCCCGCTTCACGGAGGCGCGAATATCCAGGT
GGCCGATATGTTCCATCACTTGCAGGAGAATATCAAGGACTGGAAGAGCGTGGACGAGATAGATACCTATTTCACACGAA
TGCTGAATAAGGAAGTGTATAATAAGACCGGATTGATTTACGGTATCGGTCATGCTGTTTACACGATTTCCGATCCTCGT
GCGCTGTTGCTGAAAGAACTGGCTCGCGACCTTGCCCGTGAGAAAGGAAAAGAAGAGGAGTTCGCTTTCCTCGAACTGCT
TGAAGAGCGTGCCATCGCTACTTTCGGACGTGTGAAGAACAACGGAAAGACGGTTTCCAGCAATATCGACTTCTATTCGG
GCTTCGTATATGAGATGATTGGTTTGCCGCAGGAGATTTTCACTCCGCTGTTTGCCATGGCTCGTATTGTCGGCTGGTGT
GCGCACCGCAATGAGGAACTGAACTTCGAAGGCAAACGCATTATCCGTCCGGCTTATAAAAATGTTCTTGATGATCTGGC
TTATATCCCCATCAAGAAACGCTGA

Upstream 100 bases:

>100_bases
TTCACACGCGAAATTGTGGAAAGAATCGAAAAGTAAATGTAACGATTAAAAACGAAGTATTATGAAGAAAGAGTATTTGA
TTTACAAGCTCTCCGAGGAG

Downstream 100 bases:

>100_bases
TAAGAACAAATCCTTTTATGCAATAATAACTAACCTCAGACGTACATCTCGGTAATCCCTGCATGTACGTCTTGGTAATC
CCCAGTTGTACATCTTGGTA

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKEATRIDNELFPKFDVKRGLRNEDGTGVLVGLTKIGNVVGYERIPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFE
EVAYLLLSGRLPDKEELASFRELINDNMALEQKTKMNIIELEGNNIMNILSRSVLEMYRFDPDADDTSRDNLMRQSIDLI
SKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTELDARTLDLLLILQAEHGGGNNSTFTVRVTSST
GTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKDWKSVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPR
ALLLKELARDLAREKGKEEEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEIFTPLFAMARIVGWC
AHRNEELNFEGKRIIRPAYKNVLDDLAYIPIKKR

Sequences:

>Translated_434_residues
MKEATRIDNELFPKFDVKRGLRNEDGTGVLVGLTKIGNVVGYERIPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFE
EVAYLLLSGRLPDKEELASFRELINDNMALEQKTKMNIIELEGNNIMNILSRSVLEMYRFDPDADDTSRDNLMRQSIDLI
SKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTELDARTLDLLLILQAEHGGGNNSTFTVRVTSST
GTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKDWKSVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPR
ALLLKELARDLAREKGKEEEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEIFTPLFAMARIVGWC
AHRNEELNFEGKRIIRPAYKNVLDDLAYIPIKKR
>Mature_434_residues
MKEATRIDNELFPKFDVKRGLRNEDGTGVLVGLTKIGNVVGYERIPGGGLKPIPGKLFYRGYDVEDISHAIIKEKRFGFE
EVAYLLLSGRLPDKEELASFRELINDNMALEQKTKMNIIELEGNNIMNILSRSVLEMYRFDPDADDTSRDNLMRQSIDLI
SKFPTIIAYAYNMLRHATFGRSLHIRHPQEKLSIAENFLYMLKKDYTELDARTLDLLLILQAEHGGGNNSTFTVRVTSST
GTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKDWKSVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPR
ALLLKELARDLAREKGKEEEFAFLELLEERAIATFGRVKNNGKTVSSNIDFYSGFVYEMIGLPQEIFTPLFAMARIVGWC
AHRNEELNFEGKRIIRPAYKNVLDDLAYIPIKKR

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=358, Percent_Identity=26.2569832402235, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1786527, Length=394, Percent_Identity=32.2335025380711, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786939, Length=371, Percent_Identity=30.9973045822102, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17555174, Length=364, Percent_Identity=25.5494505494505, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319850, Length=411, Percent_Identity=25.3041362530414, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324328, Length=256, Percent_Identity=29.6875, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325257, Length=466, Percent_Identity=24.0343347639485, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640126, Length=346, Percent_Identity=26.5895953757225, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640124, Length=346, Percent_Identity=26.5895953757225, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356863, Length=367, Percent_Identity=24.5231607629428, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 49307; Mature: 49307

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEATRIDNELFPKFDVKRGLRNEDGTGVLVGLTKIGNVVGYERIPGGGLKPIPGKLFYR
CCCHHHCCHHHCCCHHHHHCCCCCCCCEEEEEHHHHCCHHCCCCCCCCCCCCCCCHHEEE
GYDVEDISHAIIKEKRFGFEEVAYLLLSGRLPDKEELASFRELINDNMALEQKTKMNIIE
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCEEE
LEGNNIMNILSRSVLEMYRFDPDADDTSRDNLMRQSIDLISKFPTIIAYAYNMLRHATFG
ECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RSLHIRHPQEKLSIAENFLYMLKKDYTELDARTLDLLLILQAEHGGGNNSTFTVRVTSST
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCEEEEEEECCC
GTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKDWKSVDEIDTYFTRMLNKEVY
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKTGLIYGIGHAVYTISDPRALLLKELARDLAREKGKEEEFAFLELLEERAIATFGRVKN
HCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NGKTVSSNIDFYSGFVYEMIGLPQEIFTPLFAMARIVGWCAHRNEELNFEGKRIIRPAYK
CCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
NVLDDLAYIPIKKR
HHHHHHHHCCCCCC
>Mature Secondary Structure
MKEATRIDNELFPKFDVKRGLRNEDGTGVLVGLTKIGNVVGYERIPGGGLKPIPGKLFYR
CCCHHHCCHHHCCCHHHHHCCCCCCCCEEEEEHHHHCCHHCCCCCCCCCCCCCCCHHEEE
GYDVEDISHAIIKEKRFGFEEVAYLLLSGRLPDKEELASFRELINDNMALEQKTKMNIIE
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCEEE
LEGNNIMNILSRSVLEMYRFDPDADDTSRDNLMRQSIDLISKFPTIIAYAYNMLRHATFG
ECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RSLHIRHPQEKLSIAENFLYMLKKDYTELDARTLDLLLILQAEHGGGNNSTFTVRVTSST
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCEEEEEEECCC
GTDTYSAIAAGIGSLKGPLHGGANIQVADMFHHLQENIKDWKSVDEIDTYFTRMLNKEVY
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NKTGLIYGIGHAVYTISDPRALLLKELARDLAREKGKEEEFAFLELLEERAIATFGRVKN
HCCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NGKTVSSNIDFYSGFVYEMIGLPQEIFTPLFAMARIVGWCAHRNEELNFEGKRIIRPAYK
CCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
NVLDDLAYIPIKKR
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]