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The map label for this gene is putA [H]

Identifier: 161486739

GI number: 161486739

Start: 557685

End: 561638

Strand: Reverse

Name: putA [H]

Synonym: Psyr_0506

Alternate gene names: 161486739

Gene position: 561638-557685 (Counterclockwise)

Preceding gene: 66043775

Following gene: 66043772

Centisome position: 9.22

GC content: 62.75

Gene sequence:

>3954_bases
ATGGCCACCACCACTCTGGGCGTCAAACTTGACGACCCGACCCGCGAGCGTTTGAAAGCCGCAGCCCACTCCATCGACCG
TACGCCGCACTGGTTGATCAAGCAGGCGATTTTCAATTACCTGGAAAAGCTCGAGAGTGGTGCAACCCTGCTGGAGCTCG
ACGGTGCTGCCGGCAAGGACAACGAAGACCGCGGCGAGCTGGCAGAAGAGGCGGGGCTGCAATGCTTTCTGGATTTTGCC
GAGAGCATTCAACCGCAGTCCGTGTTACGTGCAGCCATCACCTCCGCCTACCGCCGCCCCGAGCCGGAAGTGGTACCTAT
GCTGCTCGAGCAGGCACGCCTGAGCGCGCCGGTTGCCGAAGCCACCAACAAGATGGCCGCGTCGATTGCGGAGAAACTGC
GTAACCAGAAAAGCGCCGGCGGTCGCGCGGGCATCGTTCAGGGCCTGTTGCAGGAGTTTTCACTGTCTTCCCAGGAGGGC
GTCGCGCTGATGTGCCTGGCCGAAGCGCTGCTGCGTATTCCGGACAAGGGCACCCGCGATGCCTTGATTCGCGACAAGAT
CAGCAACGGCAACTGGCAGCCGCACCTGGGCAACAGCCCGTCGCTGTTCGTCAACGCCGCCACCTGGGGCCTGCTGCTGA
CAGGCAGGCTGGTCGCCACTCACAATGAAGCGGGCCTTACATCCTCGCTGAGCCGCATCATCGGCAAAAGCGGCGAACCG
ATGATCCGCAAGGGCGTCGACATGGCCATGCGCCTGATGGGCGAGCAGTTCGTCACCGGCGAAACCATCGGTGAAGCCCT
GGCCAATGCCAGTCGCTTCGAAGCCAAGGGCTTTCGCTACTCCTACGACATGCTGGGTGAAGCGGCGCTGACCGAACATG
ACGCGCAGAAGTACCTGGCGTCCTACGAGCAGGCTATCCACTCCATCGGCAAAGCCTCGCACGGTCGCGGCATCTACGAA
GGTCCGGGGATTTCCATCAAGCTGTCGGCGCTGCACCCGCGCTACAGCCGCGCCCAGTACGAGCGGGTGATGGATGAACT
GTACCCGCGCCTGCTGTCGCTGACCCTGCTCGCCAAGCAGTACGACATCGGCCTGAACATCGACGCCGAAGAAGCCGATC
GCCTGGAGCTGTCGCTGGATCTGCTCGAGCGCCTGTGTTTCGAACCACAGCTCACCGGCTGGAATGGCATCGGCTTCGTG
ATTCAGGCGTATCAGAAGCGCTGCCCTTATGTGATCGATTACGTGATCGACCTGGCGCGCCGCAGCCGCCATCGTCTGAT
GATCCGTCTGGTCAAGGGCGCGTACTGGGACAGCGAGATCAAGCGCGCCCAGGTCGAAGGCCTGGAAGGCTATCCGGTGT
ACACGCGCAAGGTGTACACCGACGTGTCCTACATCGCCTGCGCCCGCAAGTTGCTCGCGGCACCGGAAGTCATCTATCCA
CAATTTGCCACACACAACGCCCACACCCTGGCGGCGATCTACCAGATCGCCGGGCAGAATTATTACCCTGGCCAGTATGA
ATTCCAGTGCCTGCACGGCATGGGCGAGCCGTTGTATGAGCAGGTTGTAGGCAAAGTCGCCGACGGCAAACTGAATCGTC
CTTGCCGCGTGTACGCCCCGGTTGGCACCCATGAAACGCTGCTGGCCTATCTGGTGCGTCGCCTGCTCGAAAACGGCGCC
AACACCTCGTTCGTCAACCGGATTGCCGACCACTCGATCTCGATTCAGGAACTGGTCGCCGATCCGGTCAGCCAGATCGA
ACGCATGGCGACCCAGGAAGGCGGTTTCGGCCTGCCGCACCCACGCATTCCGCTGCCACGTGACCTGTACGGAACCGAAC
GCGCCAACTCCAGCGGCATCGACATGGCCAACGAACATCGTCTGGCTTCGCTGTCTTCGGCCCTGCTGGCTACCGCGCAC
AACGACTGGAAAGCCGCCCCGATGCTGGGCTGCCCGGCCAGCGCAGGCACGTTGAGTGCTGCCTTGAACCCATCGGACCT
GCGTGACGTGGTCGGTCATGTACAGGAAGCGTCCCTGCAGGATGTCGATAACGCCATCCAGTGCGCCTTGAGCGCCGGTC
CGATCTGGCAGGCCACTCCGCCTGTCGAGCGCGCTGCGATTCTGGAGCGTGCCGCTGACTTGATGGAGGCTGAAATCCAG
CCGTTGATGGGCCTGCTGGTCCGTGAAGCGGGCAAGACCTTCGCCAACGCTATCGCCGAAGTGCGCGAAGCCGTGGACTT
CCTGCGTTACTACGCCGTGCAGGCGCGCAACGACTTCACCAACGACGGCCACCGTCCGTTGGGGCCGGTGGTCTGCATCA
GCCCGTGGAACTTCCCGCTGGCGATTTTCAGTGGTCAGGTAGCTGCTGCATTGGCTGCCGGTAACCCGGTGCTGGCCAAA
CCTGCCGAGCAGACGCCGCTGATCGCCGCACAGGCCGTGCGCCTGCTGCTTGAAGCGGGCATTCCGGAAGGCGTAGTGCA
ATTGCTGCCGGGTCGCGGCGAAACCGTAGGTGCCGGACTGGTCGGCGATGAACGTGTGAAGGGTGTCATGTTTACCGGTT
CAACCGAGGTAGCCCGCCTGCTGCAGCGCAACGTCGCAGGTCGCCTCGACTCACAGGGTCGCCCCATTCCGCTGATCGCC
GAAACCGGTGGCCAGAACGCGATGATCGTCGACTCTTCGGCGCTGACCGAACAGGTGGTGATCGACGTAGTGTCTTCGGC
GTTCGACAGCGCCGGTCAGCGCTGCTCGGCACTGCGCGTGCTGTGCCTGCAGGAAGATTCTGCCGACCGCGTCATCGAAA
TGCTCAAGGGCGCGATGGCCGAGAACCGCCTCGGCAATCCGGAGCGCCTGTCGGTAGACATCGGCCCGGTGATCGACGCA
GAGGCCAAGGCCGGTATCGAAAAACACATCCAGGCCATGCGCGACAAGGGCCGCACGGTCTATCAGGTGGCCATCGCCGA
CAGCGCCGAACTCAAGCGTGGCACTTATGTGATGCCGACCCTGATCGAACTGGAAAGCTTCGATGAGCTGCAACGCGAAA
TCTTCGGGCCGGTACTGCACGTGGTGCGTTACAAGCGCAAGGAGCTTGGCCTGCTGATCGATCAGATCAATGCCTCCGGT
TATGGCCTGACCCTGGGCGTGCACACGCGCATCGACGAGACCATCGCCAAGGTCATCGACAACGTCAATGCCGGCAACGT
CTACGTCAACCGCAACATCGTCGGCGCCGTGGTGGGTGTTCAGCCATTCGGCGGCGAAGGCCTGTCCGGCACCGGCCCCA
AAGCGGGTGGCCCGTTGTACCTGTATCGCCTGCTGTCGACGCGTCCGCAGGATGCTATCGAGAAATCGTTCGTCCGCAGC
GACGCGCTGTCTGCGCCGGATACCCGCCTGCGTGAAGTCCTCGGCAAGCCGTTGCAGGCACTGAAGGCCTGGGCTGCCAG
CAACCAGCAAAGCGATCTGGACGCGCTGTGCAGTCAATACGCCGAGCAATCGCAAAGCGGCATCACCCGCCAGTTGGCAG
GCCCGACCGGCGAACGCAACAGCTACGCGATCCTGCCGCGTGAACACGTACTTTGCCTGGCTGACGACGAGAACGACCTG
CTGATTCAACTGGCAGCCGTACTGGCGGTCGGCAGCTCTGCCGTGTGGCCGGAAACCGACATCGGCAAACCGCTGCGTGC
TCGCCTGCCAAAGGACGTTCAGGCGCGCATCAAACTGATACCTGACTGGGCCAAGGACGAAGTCATCTTCGACGCCGTCC
TGCACCATGGCGACTCCGATCAGCTACGTGCCATCTGCCAGCAGATCGCACAACGCAGCGGTGCCATCGTCGGCGTAAAC
GGCCTGTCCCACGGCGAAACCAACGTACCGCTGGAACGTCTGGTGATCGAGCGGGCATTGAGCGTCAACACTGCGGCGGC
GGGTGGCAATGCGAGCCTGATGACGATCGGCTGA

Upstream 100 bases:

>100_bases
TCTGCAAATCGGGTTGCACCCGGTTGCACCCCACCCTGTCCCGAGGCTAATCTGCGCCAAAGCCGATGCCACTTCCACGT
GGCTATAAAGAGGACAACAC

Downstream 100 bases:

>100_bases
TGCCGCGCGGTAACAGATGACGCAGAGCGTCAAGAACGGCATTCCCACGCTGGAGCGTGCGCAACGAGAGGTGTCTGAAA
GACACCGACCGTTCCCCTGC

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1317; Mature: 1316

Protein sequence:

>1317_residues
MATTTLGVKLDDPTRERLKAAAHSIDRTPHWLIKQAIFNYLEKLESGATLLELDGAAGKDNEDRGELAEEAGLQCFLDFA
ESIQPQSVLRAAITSAYRRPEPEVVPMLLEQARLSAPVAEATNKMAASIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEG
VALMCLAEALLRIPDKGTRDALIRDKISNGNWQPHLGNSPSLFVNAATWGLLLTGRLVATHNEAGLTSSLSRIIGKSGEP
MIRKGVDMAMRLMGEQFVTGETIGEALANASRFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYE
GPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFV
IQAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLAAPEVIYP
QFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLNRPCRVYAPVGTHETLLAYLVRRLLENGA
NTSFVNRIADHSISIQELVADPVSQIERMATQEGGFGLPHPRIPLPRDLYGTERANSSGIDMANEHRLASLSSALLATAH
NDWKAAPMLGCPASAGTLSAALNPSDLRDVVGHVQEASLQDVDNAIQCALSAGPIWQATPPVERAAILERAADLMEAEIQ
PLMGLLVREAGKTFANAIAEVREAVDFLRYYAVQARNDFTNDGHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAK
PAEQTPLIAAQAVRLLLEAGIPEGVVQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNVAGRLDSQGRPIPLIA
ETGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAENRLGNPERLSVDIGPVIDA
EAKAGIEKHIQAMRDKGRTVYQVAIADSAELKRGTYVMPTLIELESFDELQREIFGPVLHVVRYKRKELGLLIDQINASG
YGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPQDAIEKSFVRS
DALSAPDTRLREVLGKPLQALKAWAASNQQSDLDALCSQYAEQSQSGITRQLAGPTGERNSYAILPREHVLCLADDENDL
LIQLAAVLAVGSSAVWPETDIGKPLRARLPKDVQARIKLIPDWAKDEVIFDAVLHHGDSDQLRAICQQIAQRSGAIVGVN
GLSHGETNVPLERLVIERALSVNTAAAGGNASLMTIG

Sequences:

>Translated_1317_residues
MATTTLGVKLDDPTRERLKAAAHSIDRTPHWLIKQAIFNYLEKLESGATLLELDGAAGKDNEDRGELAEEAGLQCFLDFA
ESIQPQSVLRAAITSAYRRPEPEVVPMLLEQARLSAPVAEATNKMAASIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEG
VALMCLAEALLRIPDKGTRDALIRDKISNGNWQPHLGNSPSLFVNAATWGLLLTGRLVATHNEAGLTSSLSRIIGKSGEP
MIRKGVDMAMRLMGEQFVTGETIGEALANASRFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYE
GPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFV
IQAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLAAPEVIYP
QFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLNRPCRVYAPVGTHETLLAYLVRRLLENGA
NTSFVNRIADHSISIQELVADPVSQIERMATQEGGFGLPHPRIPLPRDLYGTERANSSGIDMANEHRLASLSSALLATAH
NDWKAAPMLGCPASAGTLSAALNPSDLRDVVGHVQEASLQDVDNAIQCALSAGPIWQATPPVERAAILERAADLMEAEIQ
PLMGLLVREAGKTFANAIAEVREAVDFLRYYAVQARNDFTNDGHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAK
PAEQTPLIAAQAVRLLLEAGIPEGVVQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNVAGRLDSQGRPIPLIA
ETGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAENRLGNPERLSVDIGPVIDA
EAKAGIEKHIQAMRDKGRTVYQVAIADSAELKRGTYVMPTLIELESFDELQREIFGPVLHVVRYKRKELGLLIDQINASG
YGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPQDAIEKSFVRS
DALSAPDTRLREVLGKPLQALKAWAASNQQSDLDALCSQYAEQSQSGITRQLAGPTGERNSYAILPREHVLCLADDENDL
LIQLAAVLAVGSSAVWPETDIGKPLRARLPKDVQARIKLIPDWAKDEVIFDAVLHHGDSDQLRAICQQIAQRSGAIVGVN
GLSHGETNVPLERLVIERALSVNTAAAGGNASLMTIG
>Mature_1316_residues
ATTTLGVKLDDPTRERLKAAAHSIDRTPHWLIKQAIFNYLEKLESGATLLELDGAAGKDNEDRGELAEEAGLQCFLDFAE
SIQPQSVLRAAITSAYRRPEPEVVPMLLEQARLSAPVAEATNKMAASIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGV
ALMCLAEALLRIPDKGTRDALIRDKISNGNWQPHLGNSPSLFVNAATWGLLLTGRLVATHNEAGLTSSLSRIIGKSGEPM
IRKGVDMAMRLMGEQFVTGETIGEALANASRFEAKGFRYSYDMLGEAALTEHDAQKYLASYEQAIHSIGKASHGRGIYEG
PGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQYDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVI
QAYQKRCPYVIDYVIDLARRSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLAAPEVIYPQ
FATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLNRPCRVYAPVGTHETLLAYLVRRLLENGAN
TSFVNRIADHSISIQELVADPVSQIERMATQEGGFGLPHPRIPLPRDLYGTERANSSGIDMANEHRLASLSSALLATAHN
DWKAAPMLGCPASAGTLSAALNPSDLRDVVGHVQEASLQDVDNAIQCALSAGPIWQATPPVERAAILERAADLMEAEIQP
LMGLLVREAGKTFANAIAEVREAVDFLRYYAVQARNDFTNDGHRPLGPVVCISPWNFPLAIFSGQVAAALAAGNPVLAKP
AEQTPLIAAQAVRLLLEAGIPEGVVQLLPGRGETVGAGLVGDERVKGVMFTGSTEVARLLQRNVAGRLDSQGRPIPLIAE
TGGQNAMIVDSSALTEQVVIDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAENRLGNPERLSVDIGPVIDAE
AKAGIEKHIQAMRDKGRTVYQVAIADSAELKRGTYVMPTLIELESFDELQREIFGPVLHVVRYKRKELGLLIDQINASGY
GLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSTRPQDAIEKSFVRSD
ALSAPDTRLREVLGKPLQALKAWAASNQQSDLDALCSQYAEQSQSGITRQLAGPTGERNSYAILPREHVLCLADDENDLL
IQLAAVLAVGSSAVWPETDIGKPLRARLPKDVQARIKLIPDWAKDEVIFDAVLHHGDSDQLRAICQQIAQRSGAIVGVNG
LSHGETNVPLERLVIERALSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=475, Percent_Identity=30.9473684210526, Blast_Score=193, Evalue=8e-49,
Organism=Homo sapiens, GI21361176, Length=461, Percent_Identity=32.9718004338395, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI25777724, Length=482, Percent_Identity=30.7053941908714, Blast_Score=187, Evalue=8e-47,
Organism=Homo sapiens, GI25777730, Length=475, Percent_Identity=32.6315789473684, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI238859541, Length=461, Percent_Identity=32.7548806941432, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI25777736, Length=461, Percent_Identity=32.7548806941432, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI25777734, Length=461, Percent_Identity=32.7548806941432, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI25777732, Length=453, Percent_Identity=31.7880794701987, Blast_Score=183, Evalue=1e-45,
Organism=Homo sapiens, GI25777728, Length=416, Percent_Identity=31.25, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI21614513, Length=421, Percent_Identity=30.8788598574822, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI188035924, Length=446, Percent_Identity=30.2690582959641, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI310128103, Length=446, Percent_Identity=30.2690582959641, Blast_Score=156, Evalue=2e-37,
Organism=Homo sapiens, GI310128093, Length=446, Percent_Identity=29.8206278026906, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=27.7027027027027, Blast_Score=154, Evalue=6e-37,
Organism=Homo sapiens, GI238814322, Length=419, Percent_Identity=27.4463007159904, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI4507229, Length=415, Percent_Identity=29.8795180722892, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI25777721, Length=428, Percent_Identity=28.7383177570093, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI115387104, Length=462, Percent_Identity=25.974025974026, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI25777726, Length=482, Percent_Identity=26.9709543568465, Blast_Score=134, Evalue=7e-31,
Organism=Homo sapiens, GI310128091, Length=388, Percent_Identity=30.6701030927835, Blast_Score=130, Evalue=7e-30,
Organism=Homo sapiens, GI25952152, Length=440, Percent_Identity=27.0454545454545, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI11095441, Length=427, Percent_Identity=26.9320843091335, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI310128087, Length=268, Percent_Identity=30.9701492537313, Blast_Score=106, Evalue=2e-22,
Organism=Homo sapiens, GI71773324, Length=390, Percent_Identity=27.1794871794872, Blast_Score=104, Evalue=6e-22,
Organism=Homo sapiens, GI206597441, Length=445, Percent_Identity=27.6404494382022, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI206597439, Length=445, Percent_Identity=27.6404494382022, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI22907049, Length=445, Percent_Identity=27.6404494382022, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI4502043, Length=334, Percent_Identity=27.8443113772455, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI238814371, Length=334, Percent_Identity=27.8443113772455, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=29.9694189602446, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI310128095, Length=314, Percent_Identity=29.9363057324841, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=32.046332046332, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI73695881, Length=335, Percent_Identity=26.5671641791045, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI73695879, Length=335, Percent_Identity=26.5671641791045, Blast_Score=91, Evalue=7e-18,
Organism=Homo sapiens, GI4557303, Length=341, Percent_Identity=26.9794721407625, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI73466520, Length=341, Percent_Identity=26.9794721407625, Blast_Score=90, Evalue=2e-17,
Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=29.7674418604651, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128099, Length=204, Percent_Identity=30.3921568627451, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI301500698, Length=445, Percent_Identity=23.3707865168539, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI223972651, Length=423, Percent_Identity=26.241134751773, Blast_Score=73, Evalue=2e-12,
Organism=Escherichia coli, GI1787250, Length=1326, Percent_Identity=73.9064856711916, Blast_Score=1989, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=444, Percent_Identity=31.5315315315315, Blast_Score=181, Evalue=3e-46,
Organism=Escherichia coli, GI1787684, Length=456, Percent_Identity=30.7017543859649, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1787715, Length=440, Percent_Identity=32.7272727272727, Blast_Score=163, Evalue=8e-41,
Organism=Escherichia coli, GI87081896, Length=487, Percent_Identity=31.211498973306, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI1787558, Length=431, Percent_Identity=31.0904872389791, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1788042, Length=445, Percent_Identity=29.8876404494382, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1786504, Length=468, Percent_Identity=27.991452991453, Blast_Score=149, Evalue=9e-37,
Organism=Escherichia coli, GI87082295, Length=442, Percent_Identity=31.2217194570136, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI87081926, Length=434, Percent_Identity=26.7281105990783, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1787653, Length=413, Percent_Identity=23.4866828087167, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144435, Length=463, Percent_Identity=32.1814254859611, Blast_Score=186, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17534447, Length=464, Percent_Identity=32.1120689655172, Blast_Score=185, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17562198, Length=462, Percent_Identity=31.8181818181818, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI115534176, Length=467, Percent_Identity=31.4775160599572, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32564736, Length=409, Percent_Identity=32.7628361858191, Blast_Score=170, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=383, Percent_Identity=31.8537859007833, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI133930964, Length=499, Percent_Identity=27.4549098196393, Blast_Score=157, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI25143874, Length=438, Percent_Identity=28.9954337899543, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI25143876, Length=438, Percent_Identity=28.9954337899543, Blast_Score=150, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI32564151, Length=424, Percent_Identity=29.7169811320755, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=460, Percent_Identity=26.0869565217391, Blast_Score=130, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=454, Percent_Identity=27.7533039647577, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71986308, Length=428, Percent_Identity=26.1682242990654, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.410835214447, Blast_Score=116, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=299, Percent_Identity=31.1036789297659, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=25.75, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17564084, Length=331, Percent_Identity=26.5861027190332, Blast_Score=97, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=332, Percent_Identity=25.9036144578313, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=332, Percent_Identity=25.9036144578313, Blast_Score=94, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=332, Percent_Identity=25.9036144578313, Blast_Score=94, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6325196, Length=455, Percent_Identity=32.3076923076923, Blast_Score=188, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324950, Length=460, Percent_Identity=30, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6321826, Length=478, Percent_Identity=30.7531380753138, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320917, Length=451, Percent_Identity=31.0421286031042, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=472, Percent_Identity=28.6016949152542, Blast_Score=164, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=472, Percent_Identity=29.4491525423729, Blast_Score=164, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=447, Percent_Identity=27.7404921700224, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=399, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=328, Percent_Identity=24.6951219512195, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129399, Length=477, Percent_Identity=31.4465408805031, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24650465, Length=462, Percent_Identity=29.8701298701299, Blast_Score=177, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24668425, Length=476, Percent_Identity=29.2016806722689, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24668417, Length=476, Percent_Identity=29.2016806722689, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24668413, Length=476, Percent_Identity=29.2016806722689, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24585660, Length=458, Percent_Identity=28.82096069869, Blast_Score=166, Evalue=8e-41,
Organism=Drosophila melanogaster, GI281362580, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI62472918, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI62472926, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI62472936, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI21356737, Length=442, Percent_Identity=28.0542986425339, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI28571806, Length=480, Percent_Identity=28.75, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571802, Length=480, Percent_Identity=28.5416666666667, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571800, Length=480, Percent_Identity=28.5416666666667, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571798, Length=480, Percent_Identity=28.75, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571796, Length=480, Percent_Identity=28.75, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI28571794, Length=480, Percent_Identity=28.75, Blast_Score=153, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24666674, Length=451, Percent_Identity=29.2682926829268, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574525, Length=462, Percent_Identity=27.4891774891775, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24638876, Length=420, Percent_Identity=25.952380952381, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24638878, Length=420, Percent_Identity=25.952380952381, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281360299, Length=355, Percent_Identity=29.0140845070423, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281360297, Length=355, Percent_Identity=29.0140845070423, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281360295, Length=355, Percent_Identity=29.0140845070423, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24586250, Length=355, Percent_Identity=29.0140845070423, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI281360301, Length=351, Percent_Identity=29.0598290598291, Blast_Score=97, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45552499, Length=355, Percent_Identity=27.887323943662, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360303, Length=351, Percent_Identity=27.9202279202279, Blast_Score=92, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 142781; Mature: 142650

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00024 HEMOPEXIN ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTTLGVKLDDPTRERLKAAAHSIDRTPHWLIKQAIFNYLEKLESGATLLELDGAAGKD
CCCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NEDRGELAEEAGLQCFLDFAESIQPQSVLRAAITSAYRRPEPEVVPMLLEQARLSAPVAE
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
ATNKMAASIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGVALMCLAEALLRIPDKGTRD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
ALIRDKISNGNWQPHLGNSPSLFVNAATWGLLLTGRLVATHNEAGLTSSLSRIIGKSGEP
HHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCH
MIRKGVDMAMRLMGEQFVTGETIGEALANASRFEAKGFRYSYDMLGEAALTEHDAQKYLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
SYEQAIHSIGKASHGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQ
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVIQAYQKRCPYVIDYVIDLAR
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
RSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLAAPEVIYP
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHCC
QFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLNRPCRVYAP
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEC
VGTHETLLAYLVRRLLENGANTSFVNRIADHSISIQELVADPVSQIERMATQEGGFGLPH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRIPLPRDLYGTERANSSGIDMANEHRLASLSSALLATAHNDWKAAPMLGCPASAGTLSA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
ALNPSDLRDVVGHVQEASLQDVDNAIQCALSAGPIWQATPPVERAAILERAADLMEAEIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLMGLLVREAGKTFANAIAEVREAVDFLRYYAVQARNDFTNDGHRPLGPVVCISPWNFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCH
AIFSGQVAAALAAGNPVLAKPAEQTPLIAAQAVRLLLEAGIPEGVVQLLPGRGETVGAGL
HHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCC
VGDERVKGVMFTGSTEVARLLQRNVAGRLDSQGRPIPLIAETGGQNAMIVDSSALTEQVV
CCCHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHH
IDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAENRLGNPERLSVDIGPVIDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
EAKAGIEKHIQAMRDKGRTVYQVAIADSAELKRGTYVMPTLIELESFDELQREIFGPVLH
HHHCCHHHHHHHHHHCCCEEEEEEECCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
VVRYKRKELGLLIDQINASGYGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGV
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEC
QPFGGEGLSGTGPKAGGPLYLYRLLSTRPQDAIEKSFVRSDALSAPDTRLREVLGKPLQA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKAWAASNQQSDLDALCSQYAEQSQSGITRQLAGPTGERNSYAILPREHVLCLADDENDL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCCEEEEECCCCHH
LIQLAAVLAVGSSAVWPETDIGKPLRARLPKDVQARIKLIPDWAKDEVIFDAVLHHGDSD
HHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHEECCCCCCHHHHHHHHHHCCCHH
QLRAICQQIAQRSGAIVGVNGLSHGETNVPLERLVIERALSVNTAAAGGNASLMTIG
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
ATTTLGVKLDDPTRERLKAAAHSIDRTPHWLIKQAIFNYLEKLESGATLLELDGAAGKD
CCEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NEDRGELAEEAGLQCFLDFAESIQPQSVLRAAITSAYRRPEPEVVPMLLEQARLSAPVAE
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
ATNKMAASIAEKLRNQKSAGGRAGIVQGLLQEFSLSSQEGVALMCLAEALLRIPDKGTRD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHH
ALIRDKISNGNWQPHLGNSPSLFVNAATWGLLLTGRLVATHNEAGLTSSLSRIIGKSGEP
HHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHCEEEEECCCCCHHHHHHHHHCCCCCH
MIRKGVDMAMRLMGEQFVTGETIGEALANASRFEAKGFRYSYDMLGEAALTEHDAQKYLA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
SYEQAIHSIGKASHGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLLAKQ
HHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YDIGLNIDAEEADRLELSLDLLERLCFEPQLTGWNGIGFVIQAYQKRCPYVIDYVIDLAR
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
RSRHRLMIRLVKGAYWDSEIKRAQVEGLEGYPVYTRKVYTDVSYIACARKLLAAPEVIYP
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHCC
QFATHNAHTLAAIYQIAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLNRPCRVYAP
CCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEC
VGTHETLLAYLVRRLLENGANTSFVNRIADHSISIQELVADPVSQIERMATQEGGFGLPH
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRIPLPRDLYGTERANSSGIDMANEHRLASLSSALLATAHNDWKAAPMLGCPASAGTLSA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEE
ALNPSDLRDVVGHVQEASLQDVDNAIQCALSAGPIWQATPPVERAAILERAADLMEAEIQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
PLMGLLVREAGKTFANAIAEVREAVDFLRYYAVQARNDFTNDGHRPLGPVVCISPWNFPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCH
AIFSGQVAAALAAGNPVLAKPAEQTPLIAAQAVRLLLEAGIPEGVVQLLPGRGETVGAGL
HHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEECCCC
VGDERVKGVMFTGSTEVARLLQRNVAGRLDSQGRPIPLIAETGGQNAMIVDSSALTEQVV
CCCHHCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECHHHHHHHH
IDVVSSAFDSAGQRCSALRVLCLQEDSADRVIEMLKGAMAENRLGNPERLSVDIGPVIDA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
EAKAGIEKHIQAMRDKGRTVYQVAIADSAELKRGTYVMPTLIELESFDELQREIFGPVLH
HHHCCHHHHHHHHHHCCCEEEEEEECCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
VVRYKRKELGLLIDQINASGYGLTLGVHTRIDETIAKVIDNVNAGNVYVNRNIVGAVVGV
HHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEC
QPFGGEGLSGTGPKAGGPLYLYRLLSTRPQDAIEKSFVRSDALSAPDTRLREVLGKPLQA
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LKAWAASNQQSDLDALCSQYAEQSQSGITRQLAGPTGERNSYAILPREHVLCLADDENDL
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCCEEEEECCCCHH
LIQLAAVLAVGSSAVWPETDIGKPLRARLPKDVQARIKLIPDWAKDEVIFDAVLHHGDSD
HHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHEECCCCCCHHHHHHHHHHCCCHH
QLRAICQQIAQRSGAIVGVNGLSHGETNVPLERLVIERALSVNTAAAGGNASLMTIG
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]