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The map label for this gene is fecC [H]

Identifier: 161486738

GI number: 161486738

Start: 754569

End: 755543

Strand: Reverse

Name: fecC [H]

Synonym: Psyr_0666

Alternate gene names: 161486738

Gene position: 755543-754569 (Counterclockwise)

Preceding gene: 66043934

Following gene: 66043932

Centisome position: 12.4

GC content: 66.15

Gene sequence:

>975_bases
ATGGCGGGCGTGATCATCGCGGCCTGCCTGGGATTGTTCTGGGTGTCGCTGTTTGCCCTGTCGTCGTTCAGCATTCGCCA
GGTGGATGCCTGGAACGGACTGATCACACAGGGCCGCGAGGGCGGCAATATCGCTTACATCGTCGCGCAACTGCGCGTGC
CACGTGCCTTGTGCGCGGCATTGGTCGGTGCCTGCCTGGGCGTGGCCGGCGCGTTGATGCAGGGCATCACCCGCAACCGT
CTGGCCTCCCCGTCATTGTTTGGCGTTACCGCAGGCGCCGCATTGGGGCTGGCGCTGTTTTCCACCGGTCTGGTCGCCCT
GCCCTTCCCCGGTGGCGCACTGCTGATGACCTGCCTTGGCGGTGCGCTGGCGTGGATCACCGTGTTCAGTCTTGGCGGTG
CCTGGTCACCCGCCACGGCTCAAGGTCGACTGGTGCTGGCAGGTGTCGCGGTAGCCGCCCTGTGCGCCGCATTGACCCGC
CTCACGGTAATTCTCGTCGAGGCGCAGGCGCAAAGTGTCCTCAACTGGCTGGCTGGGTCGCTGGCCAATGTCGGTGCCGC
ACAATTGCAACTGCTCTGGCCGTGCACGCTGATCGGCGTGGTGCTGGCGGTGGCCTGTGCGCCACGCCTTAACCTGATCA
ACCTCGGCGAAGACGCCGCGCGTTCGCTGGGCGTGCGTATCGGCGCGTTGCGCATGCTGGTATTCGTGGTCAGCCTGCTG
CTGGTCGGTGCCAGTGTCTGTGCAGTCGGGCCGATCGGCTTTGTCGGCCTGATCGCGCCGAACATCGCTCGCCAATGGCT
GGGCAATGACTACCGCTGGCTGATCCCGATCAGCGCCGGCCTGGGCGCGGCCATCGTGCTGGCCTCGGACCTGATCAGCC
GCGCCGTGGCCTTCCCGGTGGAAACACCGGCCGGGGTGGTGACGGCATTGATCGGCGCGCCGTTCTTTCTGTTTCTAGCC
AGGCGTGCGCTATGA

Upstream 100 bases:

>100_bases
CAATCGCGGGATCATGGCCTCCGAGCAGATCGCCGACGATGCGCTTGCCGTGCTCAAGGGCGGCAAGGCCGTGCTGAACC
CGTAAATGCGCCGCTGGCTG

Downstream 100 bases:

>100_bases
ACCACCCGCGCGCACGGCTGTTGCTGCTGATGACCCTGCTGGCACTCGCCCTGCTGCTGGGCCTCAGCGCTGGCACCGTG
TGGCTGACACCCGGTGCCGT

Product: iron-dicitrate transporter permease subunit

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate transport system permease protein fecC [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAGVIIAACLGLFWVSLFALSSFSIRQVDAWNGLITQGREGGNIAYIVAQLRVPRALCAALVGACLGVAGALMQGITRNR
LASPSLFGVTAGAALGLALFSTGLVALPFPGGALLMTCLGGALAWITVFSLGGAWSPATAQGRLVLAGVAVAALCAALTR
LTVILVEAQAQSVLNWLAGSLANVGAAQLQLLWPCTLIGVVLAVACAPRLNLINLGEDAARSLGVRIGALRMLVFVVSLL
LVGASVCAVGPIGFVGLIAPNIARQWLGNDYRWLIPISAGLGAAIVLASDLISRAVAFPVETPAGVVTALIGAPFFLFLA
RRAL

Sequences:

>Translated_324_residues
MAGVIIAACLGLFWVSLFALSSFSIRQVDAWNGLITQGREGGNIAYIVAQLRVPRALCAALVGACLGVAGALMQGITRNR
LASPSLFGVTAGAALGLALFSTGLVALPFPGGALLMTCLGGALAWITVFSLGGAWSPATAQGRLVLAGVAVAALCAALTR
LTVILVEAQAQSVLNWLAGSLANVGAAQLQLLWPCTLIGVVLAVACAPRLNLINLGEDAARSLGVRIGALRMLVFVVSLL
LVGASVCAVGPIGFVGLIAPNIARQWLGNDYRWLIPISAGLGAAIVLASDLISRAVAFPVETPAGVVTALIGAPFFLFLA
RRAL
>Mature_323_residues
AGVIIAACLGLFWVSLFALSSFSIRQVDAWNGLITQGREGGNIAYIVAQLRVPRALCAALVGACLGVAGALMQGITRNRL
ASPSLFGVTAGAALGLALFSTGLVALPFPGGALLMTCLGGALAWITVFSLGGAWSPATAQGRLVLAGVAVAALCAALTRL
TVILVEAQAQSVLNWLAGSLANVGAAQLQLLWPCTLIGVVLAVACAPRLNLINLGEDAARSLGVRIGALRMLVFVVSLLL
VGASVCAVGPIGFVGLIAPNIARQWLGNDYRWLIPISAGLGAAIVLASDLISRAVAFPVETPAGVVTALIGAPFFLFLAR
RAL

Specific function: Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=321, Percent_Identity=40.1869158878505, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1790740, Length=295, Percent_Identity=34.5762711864407, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=37.0106761565836, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786805, Length=286, Percent_Identity=38.1118881118881, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786347, Length=286, Percent_Identity=32.8671328671329, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1786804, Length=284, Percent_Identity=32.7464788732394, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32986; Mature: 32855

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVIIAACLGLFWVSLFALSSFSIRQVDAWNGLITQGREGGNIAYIVAQLRVPRALCAA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCHHHCCCCCCCEEEEEEHHHCHHHHHHH
LVGACLGVAGALMQGITRNRLASPSLFGVTAGAALGLALFSTGLVALPFPGGALLMTCLG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
GALAWITVFSLGGAWSPATAQGRLVLAGVAVAALCAALTRLTVILVEAQAQSVLNWLAGS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANVGAAQLQLLWPCTLIGVVLAVACAPRLNLINLGEDAARSLGVRIGALRMLVFVVSLL
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LVGASVCAVGPIGFVGLIAPNIARQWLGNDYRWLIPISAGLGAAIVLASDLISRAVAFPV
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
ETPAGVVTALIGAPFFLFLARRAL
CCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGVIIAACLGLFWVSLFALSSFSIRQVDAWNGLITQGREGGNIAYIVAQLRVPRALCAA
CHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCHHHCCCCCCCEEEEEEHHHCHHHHHHH
LVGACLGVAGALMQGITRNRLASPSLFGVTAGAALGLALFSTGLVALPFPGGALLMTCLG
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
GALAWITVFSLGGAWSPATAQGRLVLAGVAVAALCAALTRLTVILVEAQAQSVLNWLAGS
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANVGAAQLQLLWPCTLIGVVLAVACAPRLNLINLGEDAARSLGVRIGALRMLVFVVSLL
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LVGASVCAVGPIGFVGLIAPNIARQWLGNDYRWLIPISAGLGAAIVLASDLISRAVAFPV
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
ETPAGVVTALIGAPFFLFLARRAL
CCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]