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The map label for this gene is hscB [H]

Identifier: 161486736

GI number: 161486736

Start: 1396860

End: 1397381

Strand: Direct

Name: hscB [H]

Synonym: Psyr_1240

Alternate gene names: 161486736

Gene position: 1396860-1397381 (Clockwise)

Preceding gene: 66044487

Following gene: 66044489

Centisome position: 22.92

GC content: 58.43

Gene sequence:

>522_bases
GTGGGTACTCCCTGTCACTTCGCCCTGTTTGACCTCAAGCCCGAGTTTCAGCTTGATCTTGACCAACTGGCCACGCGCTA
CCGTGAGCTTGCGCGCAACGTGCATCCGGATCGTTTTGCGGATGCCCCCGAGCGTGAGCAGCGTGTGGCGCTGGAGCGCT
CGGCCAGTCTCAACGAGGCCTATCAGACCCTGAAAAGCCCGCCGAAAAGGGCGCGTTATCTGCTGGCAATGAACGGCAAC
GAAGTGCCGCTCGAAGTCACGGTGCATGATCCCGAGTTTCTTCTGCAGCAGATGCAATTGCGCGAAGACCTCGAGGACTT
GCAGGACGAGGCTGATCTGGCCGGCGTCGCGACCTTCAAGCGTCAGCTCAAGATCGCTCAGGACGAACTGAACCAGAGCT
TCGCAGCCTGTTGGAATGATGCTGCACAACGCGAGCACGCTGAAAAGCTGATGCGGCGTATGCAGTTTCTCGACAAGCTC
TCTGACGAAGTGCGCCAGTTAGAAGAGCGCCTCGACGATTAA

Upstream 100 bases:

>100_bases
TTCGTGCGCGAAGGGTTGAACGAAGGCTTCAAGTTCAACAATCCCAACTCGCGCGGTGAGTGCGGCTGTGGCGAAAGCTT
CAACGTCTGAGGCTTTTATT

Downstream 100 bases:

>100_bases
CCCCGCGCGGCTTCGGCCGCGCGCCAGTGATTATTCTGAACAGCATGGCTTTACTGCAGATCGCCGAACCCGGCCTGAGT
CCTCAACCGCACCAGCGTCG

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MGTPCHFALFDLKPEFQLDLDQLATRYRELARNVHPDRFADAPEREQRVALERSASLNEAYQTLKSPPKRARYLLAMNGN
EVPLEVTVHDPEFLLQQMQLREDLEDLQDEADLAGVATFKRQLKIAQDELNQSFAACWNDAAQREHAEKLMRRMQFLDKL
SDEVRQLEERLDD

Sequences:

>Translated_173_residues
MGTPCHFALFDLKPEFQLDLDQLATRYRELARNVHPDRFADAPEREQRVALERSASLNEAYQTLKSPPKRARYLLAMNGN
EVPLEVTVHDPEFLLQQMQLREDLEDLQDEADLAGVATFKRQLKIAQDELNQSFAACWNDAAQREHAEKLMRRMQFLDKL
SDEVRQLEERLDD
>Mature_172_residues
GTPCHFALFDLKPEFQLDLDQLATRYRELARNVHPDRFADAPEREQRVALERSASLNEAYQTLKSPPKRARYLLAMNGNE
VPLEVTVHDPEFLLQQMQLREDLEDLQDEADLAGVATFKRQLKIAQDELNQSFAACWNDAAQREHAEKLMRRMQFLDKLS
DEVRQLEERLDD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=161, Percent_Identity=27.3291925465839, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788876, Length=174, Percent_Identity=37.3563218390805, Blast_Score=111, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321420, Length=133, Percent_Identity=30.8270676691729, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161084223, Length=167, Percent_Identity=26.9461077844311, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20198; Mature: 20067

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTPCHFALFDLKPEFQLDLDQLATRYRELARNVHPDRFADAPEREQRVALERSASLNEA
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YQTLKSPPKRARYLLAMNGNEVPLEVTVHDPEFLLQQMQLREDLEDLQDEADLAGVATFK
HHHHHCCHHHHHEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLKIAQDELNQSFAACWNDAAQREHAEKLMRRMQFLDKLSDEVRQLEERLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GTPCHFALFDLKPEFQLDLDQLATRYRELARNVHPDRFADAPEREQRVALERSASLNEA
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YQTLKSPPKRARYLLAMNGNEVPLEVTVHDPEFLLQQMQLREDLEDLQDEADLAGVATFK
HHHHHCCHHHHHEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQLKIAQDELNQSFAACWNDAAQREHAEKLMRRMQFLDKLSDEVRQLEERLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]