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The map label for this gene is xerD

Identifier: 161486657

GI number: 161486657

Start: 660992

End: 661909

Strand: Direct

Name: xerD

Synonym: VV0665

Alternate gene names: 161486657

Gene position: 660992-661909 (Clockwise)

Preceding gene: 37678847

Following gene: 37678850

Centisome position: 19.7

GC content: 48.47

Gene sequence:

>918_bases
ATGCAACAAACGGCATCGGTTAATATGCAAGATTTTGGCTACGTAGAGCAATTTCTCGATGCGATGTGGATGGAGCGAGG
CCTCGCAGAGAATACGTTGGCCTCTTACCGCAACGATCTGATGAAGTTATTGCAGTGGATGGAGGCGAATCATTATCGGC
TCGATTTCATCAGCCTGTCTGGGCTTCAGCAATACCAAAGCTATTTGGTGGATCAAGACTACAAGCAGACTTCAAGAGCA
CGGATGTTGTCAGCGATTCGTCGTCTGTTTCAATATCTTCATCGAGAAAAAGTGCGCGCCGATGATCCTAGTGCCCTATT
GGTCAGCCCTAAATTACCGCAACGTTTGCCAAAAGACATCAGTGAAGAGCAGGTCGATGCGTTATTGGATGCGCCTGATC
CGAATGATCCGGTGGAACTGCGTGACAAAGCCATGCTTGAGCTACTGTATGCCACGGGATTGCGTGTTACCGAGCTGGTG
AGTTTAACCATGGAAAACATCAGCTTGCGTCAAGGTGTGGTGCGGGTGACGGGTAAAGGTGGCAAAGAGCGCTTAGTGCC
CATGGGGGAAAATGCCATCGACTGGATCGAAACCTTTATCAAACAAGGTCGTCCGGCGTTATTGGGTGAAACCTCTTCGG
ATGTGGTGTTTCCAAGTAAGCGTGCCAGACAAATGACCAGACAAACCTTTTGGCATCGCATCAAATTCTATGCGGTGATT
GCAGGTATCGATACTGATCATTTGTCACCACACGTCTTGAGGCACGCTTTCGCCACCCATTTATTGAACTATGGGGCCGA
TCTCAGGGTCGTACAGATGCTGCTTGGTCATAGTGACTTATCGACCACGCAAATTTATACTCACGTGGCAACAGAACGAC
TAAAACAGATTCATAGCCAACATCATCCGCGTGCTTAA

Upstream 100 bases:

>100_bases
ATTGCAGCGAATATCGCGTCCGAATGGATTTTTTATAGCATTAAATCTGTGGCTGTCTTACTCTCAGCACTGTTGATTTA
CAGTGATTTAAGGTGTGTCC

Downstream 100 bases:

>100_bases
AGCGGAATAACGACAAGGTGATTTTAATGAGCGTATTACGCCGATTAACTCTTTTAACTCTTCCTCTCTTTGTGACGGCC
TGCGGTGCTGAAGAAAGCCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQQTASVNMQDFGYVEQFLDAMWMERGLAENTLASYRNDLMKLLQWMEANHYRLDFISLSGLQQYQSYLVDQDYKQTSRA
RMLSAIRRLFQYLHREKVRADDPSALLVSPKLPQRLPKDISEEQVDALLDAPDPNDPVELRDKAMLELLYATGLRVTELV
SLTMENISLRQGVVRVTGKGGKERLVPMGENAIDWIETFIKQGRPALLGETSSDVVFPSKRARQMTRQTFWHRIKFYAVI
AGIDTDHLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHSQHHPRA

Sequences:

>Translated_305_residues
MQQTASVNMQDFGYVEQFLDAMWMERGLAENTLASYRNDLMKLLQWMEANHYRLDFISLSGLQQYQSYLVDQDYKQTSRA
RMLSAIRRLFQYLHREKVRADDPSALLVSPKLPQRLPKDISEEQVDALLDAPDPNDPVELRDKAMLELLYATGLRVTELV
SLTMENISLRQGVVRVTGKGGKERLVPMGENAIDWIETFIKQGRPALLGETSSDVVFPSKRARQMTRQTFWHRIKFYAVI
AGIDTDHLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHSQHHPRA
>Mature_305_residues
MQQTASVNMQDFGYVEQFLDAMWMERGLAENTLASYRNDLMKLLQWMEANHYRLDFISLSGLQQYQSYLVDQDYKQTSRA
RMLSAIRRLFQYLHREKVRADDPSALLVSPKLPQRLPKDISEEQVDALLDAPDPNDPVELRDKAMLELLYATGLRVTELV
SLTMENISLRQGVVRVTGKGGKERLVPMGENAIDWIETFIKQGRPALLGETSSDVVFPSKRARQMTRQTFWHRIKFYAVI
AGIDTDHLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHSQHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=68.9189189189189, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1790244, Length=302, Percent_Identity=37.7483443708609, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=28.4023668639053, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_VIBVU (Q7ZAJ0)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_759521.1
- ProteinModelPortal:   Q7ZAJ0
- SMR:   Q7ZAJ0
- GeneID:   1177483
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_0530
- HOGENOM:   HBG727654
- OMA:   YLEYGRP
- ProtClustDB:   PRK00283
- BioCyc:   VVUL216895:VV1_0530-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35087; Mature: 35087

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 179-179 ACT_SITE 251-251 ACT_SITE 254-254 ACT_SITE 277-277 ACT_SITE 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTASVNMQDFGYVEQFLDAMWMERGLAENTLASYRNDLMKLLQWMEANHYRLDFISLS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
GLQQYQSYLVDQDYKQTSRARMLSAIRRLFQYLHREKVRADDPSALLVSPKLPQRLPKDI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCC
SEEQVDALLDAPDPNDPVELRDKAMLELLYATGLRVTELVSLTMENISLRQGVVRVTGKG
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GKERLVPMGENAIDWIETFIKQGRPALLGETSSDVVFPSKRARQMTRQTFWHRIKFYAVI
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
AGIDTDHLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHSQ
ECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
HHPRA
CCCCC
>Mature Secondary Structure
MQQTASVNMQDFGYVEQFLDAMWMERGLAENTLASYRNDLMKLLQWMEANHYRLDFISLS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHH
GLQQYQSYLVDQDYKQTSRARMLSAIRRLFQYLHREKVRADDPSALLVSPKLPQRLPKDI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHCCCCC
SEEQVDALLDAPDPNDPVELRDKAMLELLYATGLRVTELVSLTMENISLRQGVVRVTGKG
CHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GKERLVPMGENAIDWIETFIKQGRPALLGETSSDVVFPSKRARQMTRQTFWHRIKFYAVI
CCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHE
AGIDTDHLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQIHSQ
ECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
HHPRA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA