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The map label for this gene is dinP [H]

Identifier: 161484857

GI number: 161484857

Start: 1080775

End: 1081833

Strand: Direct

Name: dinP [H]

Synonym: y0959

Alternate gene names: 161484857

Gene position: 1080775-1081833 (Clockwise)

Preceding gene: 22124864

Following gene: 22124868

Centisome position: 23.49

GC content: 49.2

Gene sequence:

>1059_bases
ATGCGAAAAATTATTCATGTCGATATGGATTGCTTCTTCGCGGCAGTAGAAATGCGCGACGACCCTCGCCTGCGTGATAT
CCCCCTTGCGATTGGTGGCAGTAAGGAGCGGCGTGGCGTGATCAGTACCGCTAATTATCCCGCTCGGCGTTATGGTGTTC
GCAGCGCTATGCCAACGGCGATGGCGTTTAAACTCTGCCCACAGTTAACATTGCTGCCTGGTAGAATGGCGGCTTATAAA
GAGGCCTCGCAGCATATTCGCGAAATTTTTGCCCGTTATACTCCATTGATTGAACCACTGTCATTGGATGAGGCCTATTT
GGATGTTTCTGATAGCTTGGCGTGCGGTGGCTCTGCAACATTAATCGCTCAAGAGATCCGCCAGTCTATCGCTAGTGAGC
TGAACCTGACAGCCTCCGCGGGGATTGCCCCGATAAAATTTCTTGCCAAAATCGCCTCAGAGCTGAATAAACCTAATGGC
CAGTATGTGATTACACCGAATCAGATCCAGCCCTTCCTACAGGATTTACCGCTGAGTAAAATTCCCGGTGTTGGTGCCGT
CACCGCCAAACGTTTACAGGCGCTGGGGTTGGTAACCTGTGGCGATATACAAAAATATCCATTGGCAGAGTTGTTAAAAC
ATTTTGGTAAGTTTGGTCGCGTATTGTGGGAGCGTAGTCACGGTATTGATGAACGTGAAATATCCCCAGATCGTCTACGT
AAATCCGTTGGTGTGGAGAAAACACTGGCCGAGGATATTTATGACTGGGAAAGTTGTGAGGCGTTGATCGAAGAACTTTA
TCTTGAACTGGAAACTCGTTTACGTAAGGTAAAGCCGAGCCTACACATTGCCCGGCAGGGCGTTAAGCTAAAATTTCATG
ATTTTCAGCAGACCACGCAAGAACACACATGGCCAGTATTGAATAAAGTAGATTTACTGGAGATTGCCCACGCCGCATGG
CATGAACGGCGGGTCGAGCGGGGAGTCCGTTTGGTCGGGCTGCATGTTACGTTGCTGGATCCACAACTTGAGCGGCAATT
ATTGCTTGATTGGGGCTAG

Upstream 100 bases:

>100_bases
CCTTGCATGAACTCATCGGTACGACTATAGGTTAGGAGAATCTTGAATCCTTTTATTTTGACTGTATACTTATACAGCTG
TTTGTTGTGTGGGGGATTTC

Downstream 100 bases:

>100_bases
CTATTGCACGGTGTAAATAACACCCATTTGCCCGAATCACTGGTGTGTGTCAGTTCATCGGGCTTGTCTTGTAACGGTAA
TTATTTTGGCTATTAAAGCC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRVERGVRLVGLHVTLLDPQLERQLLLDWG

Sequences:

>Translated_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRVERGVRLVGLHVTLLDPQLERQLLLDWG
>Mature_352_residues
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYK
EASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNG
QYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAW
HERRVERGVRLVGLHVTLLDPQLERQLLLDWG

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7705344, Length=383, Percent_Identity=33.9425587467363, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=29.9382716049383, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=30.1538461538462, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=34.2629482071713, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI5729982, Length=120, Percent_Identity=40, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=76.2177650429799, Blast_Score=556, Evalue=1e-160,
Organism=Escherichia coli, GI1787432, Length=219, Percent_Identity=25.5707762557078, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193205700, Length=312, Percent_Identity=35.2564102564103, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=30.8880308880309, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=300, Percent_Identity=29, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=328, Percent_Identity=30.1829268292683, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=31.4487632508834, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=31.4487632508834, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24668444, Length=120, Percent_Identity=35.8333333333333, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39686; Mature: 39686

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKVDLLEIAHAAWHERRVERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTA
CCCEEEECHHHHHHHHHCCCCCCCEECCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHH
MAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSAT
HHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCHH
LIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSK
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLR
CCCCCHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQ
HHHCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEHHHHHHHH
EHTWPVLNKVDLLEIAHAAWHERRVERGVRLVGLHVTLLDPQLERQLLLDWG
HCCCHHHCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA