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The map label for this gene is fabH [H]

Identifier: 161407970

GI number: 161407970

Start: 194437

End: 195453

Strand: Direct

Name: fabH [H]

Synonym: NATL1_02081

Alternate gene names: 161407970

Gene position: 194437-195453 (Clockwise)

Preceding gene: 124024920

Following gene: 124024922

Centisome position: 10.43

GC content: 39.13

Gene sequence:

>1017_bases
TTGATTAGCAATTCTCAATGGGACTCAGGAATATCTTTTGTGGGGTGCGGAAGCGCTACCCCTCAAAAGGTAGTTAGTAA
TCATCAACTAGGTCAGAGAGTAGATACTAGTGATGAGTGGATTCAAAGTAGAACTGGTATTGGCGAAAGAAGGGTTATTG
GAGACCATGAGTCTTTGATTGATTTAGCTACTGATGCAGCACTGAATGCAGTTGAAATGGCTAATTGGGATGTGAAAACT
ATTGATTTGATAATTCTTGCAACATCTACTCCAGAAGATTTATTTGGCTCGGCGCCTAAAATTCAATCAAATATGGGAGC
TTCCAATGCATTCGCTTTTGATTTAACTGCTGCTTGCAGTGGTTTTTTATTTGCGTTGGTAACGGCCTCACAGTATTTAG
CTTCTGGATCTGTAAAAAGAGCTGTTGTGATTGGAGCAGACCAATTATCAAAATGGGTGGATTGGGATGACAGAAAGACG
TGTGTTTTGTTTGGAGATGGAGCAGGAGCAGTAGCTCTTGAGAGCTCTGGTGATAAAAGTGGGTTGATTGGATACGATTT
GAAGTCTGATGGAAGTAAAGGAGGTTGCTTAAATCTGGCTCAATCAAATATTTTTTTAGATTTGGTTCAAGGAGTTTCGC
ATCAAAAAGGGGAATATTTGCCTATCAAAATGGAGGGAAAGGAGGTTTACAAGTTTGCAGTTAAAGAAGTTCCAATTATT
CTTGGAGAAATCCTAGAAAAATATCAAATTAAGTCTGAGAATATAGATTGGCTCTTATTGCACCAAGCTAATCAAAGAAT
TCTTGATGCTGTAGCCTCAAGATTTTCAATACCAAAAGCAAAAGTGCTTTCAAATTTGAAACATTATGGGAACACCTCAG
CAGCAACGATTCCATTGATGCTTGATGAGGCAGTCAGAGATCATAGGATTAAATCAGGAGATTTAATAGCATGTAGTGGA
TTTGGTGCTGGCTTGAGTTGGGGAGCTGCTTTGTTTTTTTGGCATGGTCCCCATTAA

Upstream 100 bases:

>100_bases
ATGGATGATTTAGCGGATTTAAATAAACCAGATGTCTTAAGGTCTGATTAGAACTGTCCTACCATGTGATTGACTTATGA
AATGAGAGCTTTTTTTAGAT

Downstream 100 bases:

>100_bases
GCTGTTTAACAATTAATCTAGAAAATCATGACTATTGCCTGGGTCTTTCCTGGACAAGGCTCTCAAAAATTAGGAATGGC
AAATTCGTTACTAGATTTGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MISNSQWDSGISFVGCGSATPQKVVSNHQLGQRVDTSDEWIQSRTGIGERRVIGDHESLIDLATDAALNAVEMANWDVKT
IDLIILATSTPEDLFGSAPKIQSNMGASNAFAFDLTAACSGFLFALVTASQYLASGSVKRAVVIGADQLSKWVDWDDRKT
CVLFGDGAGAVALESSGDKSGLIGYDLKSDGSKGGCLNLAQSNIFLDLVQGVSHQKGEYLPIKMEGKEVYKFAVKEVPII
LGEILEKYQIKSENIDWLLLHQANQRILDAVASRFSIPKAKVLSNLKHYGNTSAATIPLMLDEAVRDHRIKSGDLIACSG
FGAGLSWGAALFFWHGPH

Sequences:

>Translated_338_residues
MISNSQWDSGISFVGCGSATPQKVVSNHQLGQRVDTSDEWIQSRTGIGERRVIGDHESLIDLATDAALNAVEMANWDVKT
IDLIILATSTPEDLFGSAPKIQSNMGASNAFAFDLTAACSGFLFALVTASQYLASGSVKRAVVIGADQLSKWVDWDDRKT
CVLFGDGAGAVALESSGDKSGLIGYDLKSDGSKGGCLNLAQSNIFLDLVQGVSHQKGEYLPIKMEGKEVYKFAVKEVPII
LGEILEKYQIKSENIDWLLLHQANQRILDAVASRFSIPKAKVLSNLKHYGNTSAATIPLMLDEAVRDHRIKSGDLIACSG
FGAGLSWGAALFFWHGPH
>Mature_338_residues
MISNSQWDSGISFVGCGSATPQKVVSNHQLGQRVDTSDEWIQSRTGIGERRVIGDHESLIDLATDAALNAVEMANWDVKT
IDLIILATSTPEDLFGSAPKIQSNMGASNAFAFDLTAACSGFLFALVTASQYLASGSVKRAVVIGADQLSKWVDWDDRKT
CVLFGDGAGAVALESSGDKSGLIGYDLKSDGSKGGCLNLAQSNIFLDLVQGVSHQKGEYLPIKMEGKEVYKFAVKEVPII
LGEILEKYQIKSENIDWLLLHQANQRILDAVASRFSIPKAKVLSNLKHYGNTSAATIPLMLDEAVRDHRIKSGDLIACSG
FGAGLSWGAALFFWHGPH

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=320, Percent_Identity=42.5, Blast_Score=244, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36378; Mature: 36378

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNSQWDSGISFVGCGSATPQKVVSNHQLGQRVDTSDEWIQSRTGIGERRVIGDHESLI
CCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHH
DLATDAALNAVEMANWDVKTIDLIILATSTPEDLFGSAPKIQSNMGASNAFAFDLTAACS
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHCCCCCCHHHCCCCCCEEEEEHHHHHH
GFLFALVTASQYLASGSVKRAVVIGADQLSKWVDWDDRKTCVLFGDGAGAVALESSGDKS
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCC
GLIGYDLKSDGSKGGCLNLAQSNIFLDLVQGVSHQKGEYLPIKMEGKEVYKFAVKEVPII
CEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
LGEILEKYQIKSENIDWLLLHQANQRILDAVASRFSIPKAKVLSNLKHYGNTSAATIPLM
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHH
LDEAVRDHRIKSGDLIACSGFGAGLSWGAALFFWHGPH
HHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MISNSQWDSGISFVGCGSATPQKVVSNHQLGQRVDTSDEWIQSRTGIGERRVIGDHESLI
CCCCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHH
DLATDAALNAVEMANWDVKTIDLIILATSTPEDLFGSAPKIQSNMGASNAFAFDLTAACS
HHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHCCCCCCHHHCCCCCCEEEEEHHHHHH
GFLFALVTASQYLASGSVKRAVVIGADQLSKWVDWDDRKTCVLFGDGAGAVALESSGDKS
HHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCC
GLIGYDLKSDGSKGGCLNLAQSNIFLDLVQGVSHQKGEYLPIKMEGKEVYKFAVKEVPII
CEEEEECCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
LGEILEKYQIKSENIDWLLLHQANQRILDAVASRFSIPKAKVLSNLKHYGNTSAATIPLM
HHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHH
LDEAVRDHRIKSGDLIACSGFGAGLSWGAALFFWHGPH
HHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA