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The map label for this gene is fabD [H]

Identifier: 124024922

GI number: 124024922

Start: 195481

End: 196377

Strand: Direct

Name: fabD [H]

Synonym: NATL1_02091

Alternate gene names: 124024922

Gene position: 195481-196377 (Clockwise)

Preceding gene: 161407970

Following gene: 124024923

Centisome position: 10.48

GC content: 38.46

Gene sequence:

>897_bases
ATGACTATTGCCTGGGTCTTTCCTGGACAAGGCTCTCAAAAATTAGGAATGGCAAATTCGTTACTAGATTTGCCTGGTTC
GAGAGATAGATTTGAATTGGCATCTCAAATTCTTCGAAGAGATCTTTGGAAAATCTGTTGTGGCGAAGGGCTTCCAAACG
AAGAAATATATGATTTAAATGATACGAGAAATACTCAACCTGCACTTTTTGTTGTTGAGTCACTATTGGTTGATGATTTA
AAAAGACAAGAAAGGGAGACCAAAATAATTGCAGGACACAGTCTAGGAGAGATAGTTGGTCTTTATTCAGCAGATGTTTT
AGATGCGAAGACGGCGTTATTGCTATTAAAGAAAAGATCTGAATTGATGGCAGCTGCAGGAGGAGGAGCAATGATTGCTG
TTTTGGGCTTTGATCGAAATGAATTAGACGATTTGATTAGAGAAACTGAGGGGGCTGCAATAGCTAACGACAATAGTGAA
TCTCAAGTTGTTTTATCTGGTTCTCCAGAAGCAGTGAGGAAAGTGGCTGATAATTTAAAATGTAAAAGAGCAATTCCTTT
ACAAGTTTCAGGTGCTTTTCACTCCAAATTTATGACTGAAGCATCTCAAAGTTTTGCTGAAGAACTTGATCAGGTAACTT
TTCAAGATGCTCAAATTCCAGTTCTTAGCAATGTTGATCCTACTCCAGCTGTAAATGGTGACATATTGAAGGATCGCCTT
AAGAAACAAATGACTACGGGAGTTAGGTGGCGCGAGACTATGCATAAAATGCAAAATGAAGGAATAACTACAATGGTCGA
GATTGGACCTGGGAATGTGCTTAGTGGTCTTGCTAAACGATCAATGAAAGGTGTACTGACAAGTCAAATATCAAATTCAA
GTGATTTGGGTTATTGA

Upstream 100 bases:

>100_bases
AATAGCATGTAGTGGATTTGGTGCTGGCTTGAGTTGGGGAGCTGCTTTGTTTTTTTGGCATGGTCCCCATTAAGCTGTTT
AACAATTAATCTAGAAAATC

Downstream 100 bases:

>100_bases
TTTTGGAACAATTTAGAGTCGTTACCGGAGTTGAAAAAATCTATAAAAATAGACCTCGACAAAGTTTCGTTTATGGTTGC
GTCAGTTATCTATTCGTTTT

Product: malonyl coenzyme A-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTIAWVFPGQGSQKLGMANSLLDLPGSRDRFELASQILRRDLWKICCGEGLPNEEIYDLNDTRNTQPALFVVESLLVDDL
KRQERETKIIAGHSLGEIVGLYSADVLDAKTALLLLKKRSELMAAAGGGAMIAVLGFDRNELDDLIRETEGAAIANDNSE
SQVVLSGSPEAVRKVADNLKCKRAIPLQVSGAFHSKFMTEASQSFAEELDQVTFQDAQIPVLSNVDPTPAVNGDILKDRL
KKQMTTGVRWRETMHKMQNEGITTMVEIGPGNVLSGLAKRSMKGVLTSQISNSSDLGY

Sequences:

>Translated_298_residues
MTIAWVFPGQGSQKLGMANSLLDLPGSRDRFELASQILRRDLWKICCGEGLPNEEIYDLNDTRNTQPALFVVESLLVDDL
KRQERETKIIAGHSLGEIVGLYSADVLDAKTALLLLKKRSELMAAAGGGAMIAVLGFDRNELDDLIRETEGAAIANDNSE
SQVVLSGSPEAVRKVADNLKCKRAIPLQVSGAFHSKFMTEASQSFAEELDQVTFQDAQIPVLSNVDPTPAVNGDILKDRL
KKQMTTGVRWRETMHKMQNEGITTMVEIGPGNVLSGLAKRSMKGVLTSQISNSSDLGY
>Mature_297_residues
TIAWVFPGQGSQKLGMANSLLDLPGSRDRFELASQILRRDLWKICCGEGLPNEEIYDLNDTRNTQPALFVVESLLVDDLK
RQERETKIIAGHSLGEIVGLYSADVLDAKTALLLLKKRSELMAAAGGGAMIAVLGFDRNELDDLIRETEGAAIANDNSES
QVVLSGSPEAVRKVADNLKCKRAIPLQVSGAFHSKFMTEASQSFAEELDQVTFQDAQIPVLSNVDPTPAVNGDILKDRLK
KQMTTGVRWRETMHKMQNEGITTMVEIGPGNVLSGLAKRSMKGVLTSQISNSSDLGY

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=28.4280936454849, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=35.9477124183007, Blast_Score=160, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71984332, Length=302, Percent_Identity=27.4834437086093, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=37.4581939799331, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32507; Mature: 32375

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAWVFPGQGSQKLGMANSLLDLPGSRDRFELASQILRRDLWKICCGEGLPNEEIYDLN
CEEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
DTRNTQPALFVVESLLVDDLKRQERETKIIAGHSLGEIVGLYSADVLDAKTALLLLKKRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMAAAGGGAMIAVLGFDRNELDDLIRETEGAAIANDNSESQVVLSGSPEAVRKVADNLK
HHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHHCCC
CKRAIPLQVSGAFHSKFMTEASQSFAEELDQVTFQDAQIPVLSNVDPTPAVNGDILKDRL
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHH
KKQMTTGVRWRETMHKMQNEGITTMVEIGPGNVLSGLAKRSMKGVLTSQISNSSDLGY
HHHHHCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TIAWVFPGQGSQKLGMANSLLDLPGSRDRFELASQILRRDLWKICCGEGLPNEEIYDLN
EEEEEECCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
DTRNTQPALFVVESLLVDDLKRQERETKIIAGHSLGEIVGLYSADVLDAKTALLLLKKRS
CCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMAAAGGGAMIAVLGFDRNELDDLIRETEGAAIANDNSESQVVLSGSPEAVRKVADNLK
HHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHHCCC
CKRAIPLQVSGAFHSKFMTEASQSFAEELDQVTFQDAQIPVLSNVDPTPAVNGDILKDRL
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHH
KKQMTTGVRWRETMHKMQNEGITTMVEIGPGNVLSGLAKRSMKGVLTSQISNSSDLGY
HHHHHCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]