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The map label for this gene is asd [H]

Identifier: 161353742

GI number: 161353742

Start: 4437973

End: 4439016

Strand: Reverse

Name: asd [H]

Synonym: all3680

Alternate gene names: 161353742

Gene position: 4439016-4437973 (Counterclockwise)

Preceding gene: 17231174

Following gene: 17231171

Centisome position: 69.21

GC content: 45.88

Gene sequence:

>1044_bases
TTGTCTAAAACGTATCGTGTAGCTATTTTGGGAGCAACTGGTGCTGTCGGCACAGAGTTGCTGGAATTGTTGGAAAGCCG
GAATTTTCCGGTGGCGGAACTAAAATTATTGGCATCAGAAAGGAGCGTAGGCCGATCGCTCCCCTTTCAAGGTGAAAATA
TAATAGTAGAGGCAGTGAGCGATCGCGCCTTTGAAAATGTTGATATAGTTTTAGCCAGCGCTGGTGGTTCCACATCCAAA
GCTTGGGCATCTGTAGCGGTTGAAAAGGGTGCAGTAGTTATTGATAACTCCAGCGCCTTCCGTATGAACCCAGATGTTCC
TCTGATTGTGCCAGAGGTAAACCCCCAAGCCGCCGCCGACCACAAAGGCATCATTGCCAACCCCAACTGCACCACTATTT
TGATGACCTTGGCAGTATGGCCATTACATCAAGTTAGACCAGTGCAACGCATTGTAGCAGCAACTTACCAGTCTGCTAGT
GGTGCAGGTGCTAAAGCAATGGCAGAAGTGAAAACCCAAAGCAGTGCCATCTTGAGAGGTGAGGAACCAGTCGCCGAAGT
ATTACCTTACCCCTTAGCATTTAATTTATTTCCCCATAACTCTCCCTTGACCGATTCAGGGTATTGTGAGGAAGAGTTGA
AAATGGTCAACGAGACCCGCAAAATCTTTGGTACACAAGAAATTAGAATTACAGCTACTTGTGTACGGGTTCCCGTACTA
CGCGCCCACTCAGAAGCAATTAATCTAGAGTTCGCAGAACCATTTTCTCCAGATGAAGCTAGAGAAATTTTAAGTCAAGC
ACCTGGAGTAAAATTGCTAGAAGATTGGGGAAAAAATTACTTCCCCATGCCTATTGAAGCTAGTGGTCGTGATGAAGTTT
TAGTCGGGAGAATCCGCCAAGATATTTCTCACCCCTGTGGTTTAGAACTCTGGCTTTGTGGCGACCAAATTCGTAAAGGC
GCAGCGTTGAATGCGGTACAAATAGCCGAGTTGTTGGTAGAAAAGAATTTACTCCAACCTACAAAAGCTTATGTTGCTAG
GTAG

Upstream 100 bases:

>100_bases
AATATTTGATTATTCTTATTGTCAAAGACTGGATAAATTATAAATCTGTAAGAGACCACCAAAAACTTAACCATAACCTC
TGAGGAAGGAGGATTTTAGT

Downstream 100 bases:

>100_bases
TCAGTTGTCATTGGTCGGTGGTCATTAGCCATCATGAACTGCATCAGGTATGGGGGATTAGCGCTCTTTTATGACTCTGA
TGAAAGAAAAAAATGTAGGT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFQGENIIVEAVSDRAFENVDIVLASAGGSTSK
AWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSAS
GAGAKAMAEVKTQSSAILRGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
RAHSEAINLEFAEPFSPDEAREILSQAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKG
AALNAVQIAELLVEKNLLQPTKAYVAR

Sequences:

>Translated_347_residues
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFQGENIIVEAVSDRAFENVDIVLASAGGSTSK
AWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSAS
GAGAKAMAEVKTQSSAILRGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
RAHSEAINLEFAEPFSPDEAREILSQAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKG
AALNAVQIAELLVEKNLLQPTKAYVAR
>Mature_346_residues
SKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFQGENIIVEAVSDRAFENVDIVLASAGGSTSKA
WASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASG
AGAKAMAEVKTQSSAILRGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVLR
AHSEAINLEFAEPFSPDEAREILSQAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKGA
ALNAVQIAELLVEKNLLQPTKAYVAR

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=37.6093294460641, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=30.5322128851541, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320362, Length=393, Percent_Identity=28.498727735369, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37589; Mature: 37457

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFQGENIIVEAVS
CCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
DRAFENVDIVLASAGGSTSKAWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAAD
CCCCCCEEEEEEECCCCCHHHHHHHEEECCEEEEECCCCEEECCCCCEEEECCCCCCCCC
HKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASGAGAKAMAEVKTQSSAILRG
CCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEECC
EEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
CCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHH
RAHSEAINLEFAEPFSPDEAREILSQAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQ
HCCCHHEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DISHPCGLELWLCGDQIRKGAALNAVQIAELLVEKNLLQPTKAYVAR
HHCCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFQGENIIVEAVS
CCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
DRAFENVDIVLASAGGSTSKAWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAAD
CCCCCCEEEEEEECCCCCHHHHHHHEEECCEEEEECCCCEEECCCCCEEEECCCCCCCCC
HKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASGAGAKAMAEVKTQSSAILRG
CCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEECC
EEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
CCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHH
RAHSEAINLEFAEPFSPDEAREILSQAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQ
HCCCHHEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DISHPCGLELWLCGDQIRKGAALNAVQIAELLVEKNLLQPTKAYVAR
HHCCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]