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The map label for this gene is slyA [H]

Identifier: 161353603

GI number: 161353603

Start: 1519886

End: 1520320

Strand: Direct

Name: slyA [H]

Synonym: STM1444

Alternate gene names: 161353603

Gene position: 1519886-1520320 (Clockwise)

Preceding gene: 16764788

Following gene: 16764794

Centisome position: 31.29

GC content: 48.97

Gene sequence:

>435_bases
TTGGAATCGCCACTAGGTTCTGATCTGGCACGGTTGGTGCGCATTTGGCGTGCTCTGATTGACCATCGCCTCAAGCCTCT
GGAATTGACGCAGACACATTGGGTCACGTTGCACAATATTCATCAATTGCCGCCTGACCAGTCGCAGATTCAATTGGCTA
AAGCGATAGGCATTGAGCAGCCATCGCTGGTACGCACGTTGGATCAACTTGAAGATAAGGGGCTAATTTCGCGGCAAACC
TGCGCCAGCGATCGTCGCGCTAAGCGGATTAAACTGACCGAAAAAGCGGACGCGCTGATCGCTGAGATGGAAGAGGTCAT
TCATAAAACGCGCGGTGAAATTTTGGCTGGGATTTCTTCAGAGGAGATTGAGCTTCTGATTAAACTTATCGCCAAACTTG
AACACAATATTATGGAATTGCACTCTCACGATTGA

Upstream 100 bases:

>100_bases
TAAGCAAATTTAGCAATACATTTGTTTTGAGAATACAAATACTGCACACTATTCTAAAATCAGCATAATAACTTAGCAAG
CTAATTATAAGGAGATGAAA

Downstream 100 bases:

>100_bases
GGTGCAGGGGCATACGTGTGGCCATGTGACCACACGTAAAGCCTGGTTTAGCGTGGAGAGACGGTAACCTGGCTGCCGTT
GCTGGCCAGCACGACACGCT

Product: transcriptional regulator SlyA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQT
CASDRRAKRIKLTEKADALIAEMEEVIHKTRGEILAGISSEEIELLIKLIAKLEHNIMELHSHD

Sequences:

>Translated_144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQT
CASDRRAKRIKLTEKADALIAEMEEVIHKTRGEILAGISSEEIELLIKLIAKLEHNIMELHSHD
>Mature_144_residues
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQT
CASDRRAKRIKLTEKADALIAEMEEVIHKTRGEILAGISSEEIELLIKLIAKLEHNIMELHSHD

Specific function: Transcription regulator that either activates or represses expression of target genes. Required to activate expression of virulent genes [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081950, Length=142, Percent_Identity=89.4366197183099, Blast_Score=251, Evalue=9e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023071
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16422; Mature: 16422

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKADALIAEMEEVIHKTRGEILAGISS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEIELLIKLIAKLEHNIMELHSHD
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
PSLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKADALIAEMEEVIHKTRGEILAGISS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EEIELLIKLIAKLEHNIMELHSHD
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10385201; 11939575 [H]