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The map label for this gene is cycZ [H]

Identifier: 16127902

GI number: 16127902

Start: 3927421

End: 3928164

Strand: Direct

Name: cycZ [H]

Synonym: CC_3672

Alternate gene names: 16127902

Gene position: 3927421-3928164 (Clockwise)

Preceding gene: 16127899

Following gene: 16127903

Centisome position: 97.77

GC content: 66.67

Gene sequence:

>744_bases
ATGGACGCCCGCCACACGTTCGACTTCCTGACCAACCCCGAGCGGTTCATGGCCTTCTCGCGATGGGCCGCGCCATGGCT
TGGCGGCCTGTCCGCCGCCGCCGCCGTTATCGGGTTGACCCTGACCTTCATGGTCCCCGAGGACTATCAGCAGGGTGATA
CGGTGCGGATGATGTTCATCCATATCCCGGCCGCGTCGCTGTCGATGTTCATCTATCTTTGCCTCGGGATCGCCAGCCTG
TTGTCGCTGGTCTACCGGCATGTGCTGGCGGACCTGGCGGCGCAGGCCTGCGCGCCGATCGGCGCGGTCTATACCGTCCT
GGCCCTGATCACCGGATCGCTGTGGGGCCGGCCGATGTGGGGGACCTATTGGGTCTGGGATGCGCGCCTGACCTCGGTGC
TCGTCCTGTTGCTGTTCTATCTGGGCTACATGGCCCTGCGCGGCGCGCTCGAGGACGAACAGAAGGCCGCGCGCTCGGCC
GCCATCCTGGCCCTGGTCGGCGTGATCAATCTGCCGGTCGTGAAGTTCTCGGTCGACTGGTGGAACACCCTGCATCAGGG
CTCCTCGACCTTCTTCGCCGACAAGGGCGACCACCTGCCGGCGGTCTATGCCTGGCCGGCCGCCTTCATGGCCCTGGCCT
ATCTCGGCGGCTTTGGCGCGTTGTGGCTGGTGCGGATCCGGGCATTGGTCTGGCGTCGCAAGGCGCGGAGCCTGTCCCTG
AAGCTGGCGGAGGGCGCGCGATGA

Upstream 100 bases:

>100_bases
CCCTGCCCGCGCGGCGGAAGCGGCGCCCTTGAGGGCGCCGCTTCCCCTCCGTAGCGATACGGCCATTGCCCAGGCGCGCC
GGCCGCACTAAGCAGCCTGC

Downstream 100 bases:

>100_bases
GCTTCGACTTCGACGCGGGCAAGTACGCCGTCTATCTGTGGCCGGCTTTCGCGATTTCTGCGGTCGCCTTCGCCTGGCTT
ATCGGCGACAGCCTGGCCAT

Product: heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MDARHTFDFLTNPERFMAFSRWAAPWLGGLSAAAAVIGLTLTFMVPEDYQQGDTVRMMFIHIPAASLSMFIYLCLGIASL
LSLVYRHVLADLAAQACAPIGAVYTVLALITGSLWGRPMWGTYWVWDARLTSVLVLLLFYLGYMALRGALEDEQKAARSA
AILALVGVINLPVVKFSVDWWNTLHQGSSTFFADKGDHLPAVYAWPAAFMALAYLGGFGALWLVRIRALVWRRKARSLSL
KLAEGAR

Sequences:

>Translated_247_residues
MDARHTFDFLTNPERFMAFSRWAAPWLGGLSAAAAVIGLTLTFMVPEDYQQGDTVRMMFIHIPAASLSMFIYLCLGIASL
LSLVYRHVLADLAAQACAPIGAVYTVLALITGSLWGRPMWGTYWVWDARLTSVLVLLLFYLGYMALRGALEDEQKAARSA
AILALVGVINLPVVKFSVDWWNTLHQGSSTFFADKGDHLPAVYAWPAAFMALAYLGGFGALWLVRIRALVWRRKARSLSL
KLAEGAR
>Mature_247_residues
MDARHTFDFLTNPERFMAFSRWAAPWLGGLSAAAAVIGLTLTFMVPEDYQQGDTVRMMFIHIPAASLSMFIYLCLGIASL
LSLVYRHVLADLAAQACAPIGAVYTVLALITGSLWGRPMWGTYWVWDARLTSVLVLLLFYLGYMALRGALEDEQKAARSA
AILALVGVINLPVVKFSVDWWNTLHQGSSTFFADKGDHLPAVYAWPAAFMALAYLGGFGALWLVRIRALVWRRKARSLSL
KLAEGAR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=186, Percent_Identity=50, Blast_Score=190, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27320; Mature: 27320

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARHTFDFLTNPERFMAFSRWAAPWLGGLSAAAAVIGLTLTFMVPEDYQQGDTVRMMFI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEE
HIPAASLSMFIYLCLGIASLLSLVYRHVLADLAAQACAPIGAVYTVLALITGSLWGRPMW
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
GTYWVWDARLTSVLVLLLFYLGYMALRGALEDEQKAARSAAILALVGVINLPVVKFSVDW
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
WNTLHQGSSTFFADKGDHLPAVYAWPAAFMALAYLGGFGALWLVRIRALVWRRKARSLSL
HHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KLAEGAR
ECCCCCC
>Mature Secondary Structure
MDARHTFDFLTNPERFMAFSRWAAPWLGGLSAAAAVIGLTLTFMVPEDYQQGDTVRMMFI
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEE
HIPAASLSMFIYLCLGIASLLSLVYRHVLADLAAQACAPIGAVYTVLALITGSLWGRPMW
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
GTYWVWDARLTSVLVLLLFYLGYMALRGALEDEQKAARSAAILALVGVINLPVVKFSVDW
CEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
WNTLHQGSSTFFADKGDHLPAVYAWPAAFMALAYLGGFGALWLVRIRALVWRRKARSLSL
HHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
KLAEGAR
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]