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The map label for this gene is gltD [H]

Identifier: 16127836

GI number: 16127836

Start: 3859230

End: 3860675

Strand: Direct

Name: gltD [H]

Synonym: CC_3606

Alternate gene names: 16127836

Gene position: 3859230-3860675 (Clockwise)

Preceding gene: 16127834

Following gene: 16127837

Centisome position: 96.07

GC content: 69.02

Gene sequence:

>1446_bases
ATGGCCGAGCGCATGCTGAAATTCACGACGGTGGCCCGCAAGACGCCTGAAAAGCGCGCGGCCGCTGAGCGTTCGGGCGA
CTTTCACGAGATCTACGCCGACTTCATCGACGCAAAGGCCACCGAGCAGGCCTCGCGTTGCTCGCAGTGCGGCGTGCCGT
TCTGTCAGACGCACTGCCCGCTGCACAACAACATCCCCGACTGGCTGCGGATGACCGCCGAAGGCCGTCTGGAAGAAGCC
TACGCCCTGTCGCAGGCGACCAATTCGATGCCGGAGGTCTGCGGTCGAATTTGCCCCCAGGATCGCCTGTGCGAAGGCAA
CTGCGTGATCGAACAGTCGGGTCACGGCACGGTGACCATCGGTTCGGTCGAGCGCTACCTGACCGACAAGGCCTGGGAGA
TGGGCTGGGTCAAGCCGCTGGCCGCCGGTCCGGCGCGCGGTCAGTCGGTCGGGATCGTGGGCGCGGGCCCCGCAGGCCTG
GCCGCCGCCGAGAAGCTGCGTGAGGCCGGCTACGACGTCACCGTCTATGACCGCCACGATCGCGCCGGCGGGCTGCTGAT
CTATGGCATCCCCGGCTTCAAGCTGGAGAAGGACGTCGTCGAGCGCCGCACCCAGCGCCTAGCCGACGGCGGCGTCGTCT
TCAAGCTGGGCTTCGAGGTCGGCAAGGACGCCACGCTCGAGGACCTGCGCGCCCAGCATGACGCGGTGCTGATCGCCGTC
GGCGTCTACGCCGCGCGCGACCTGACCGTTCCGGGCGGCGGCAGCAAGGGCGTGGTTCCAGCCCTCGACTATCTGATCAC
CTCCAACCGCCTGTCCCTGGGCGACAGCGTTCCGGCCTACGACTCGGGCGAACTGAACGCCGAGGGCAAGGACGTGGTCG
TGGTCGGCGGCGGTGACACCGCCATGGACTGCGTGCGCACGGCCATCCGTCAGGGCGCCAAGTCGGTCACCTGCCTCTAT
CGCCGCGACAAGGCCAATATGCCCGGCTCGATGCGCGAAGTGGCCAACGCCGAGGAAGAAGGCGTCACCTTCGAATGGCT
GGCCGCGCCGCGCGCCCTGTCTGGCGAGGCCGAGGCCGTCACCGGCGTGCGCGCCATCCGCATGCGCTTGGGCGCGCCGG
ACGCCTCGGGCCGCCAGAGCCCCGAGGAAATCCCCGGCGGTGACTTCGACCGTCCGGCCCAGCTGGTCGTCAAGGCCCTG
GGCTTCGAGCCCGAGAACCTGCCAGAGCAGTGGTCCGCCCCGGACCTGAAGGTGACCCGTTGGGGCACCGTCAAGGCCGA
CGTCCGGAACCAGATGACCAATCTCGACGGCGTGTTCGCCGCCGGCGACATCGTGCGCGGCGCTTCGCTGGTGGTCTGGG
CGATCAAGGACGGCCGCGACGCCGCCGACGCCATCCACCGCTACCTGCTGGCCAAGGCGTCCTCGACGCTGATCGCCGCC
GAATAG

Upstream 100 bases:

>100_bases
TGGTCTTATAATTTGACCACCACATTCTTATTGCGCAAAAGAGTCCTTAAGAGCGCCGCCAGAGCAATTTTTCTCCCAAT
CCTGGGGCGAGGGAAGTCGC

Downstream 100 bases:

>100_bases
CCCTGCGACCAAGCTCCTCGTCCTTCGACAGGCTCAGGATGAGGAACTTGGACTGAGCTTCAGTAGTCCTCATCCTGAGC
TTGTCGAAGGACGAGGACGG

Product: putative oxidoreductase

Products: NA

Alternate protein names: Glutamate synthase subunit beta; GLTS beta chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MAERMLKFTTVARKTPEKRAAAERSGDFHEIYADFIDAKATEQASRCSQCGVPFCQTHCPLHNNIPDWLRMTAEGRLEEA
YALSQATNSMPEVCGRICPQDRLCEGNCVIEQSGHGTVTIGSVERYLTDKAWEMGWVKPLAAGPARGQSVGIVGAGPAGL
AAAEKLREAGYDVTVYDRHDRAGGLLIYGIPGFKLEKDVVERRTQRLADGGVVFKLGFEVGKDATLEDLRAQHDAVLIAV
GVYAARDLTVPGGGSKGVVPALDYLITSNRLSLGDSVPAYDSGELNAEGKDVVVVGGGDTAMDCVRTAIRQGAKSVTCLY
RRDKANMPGSMREVANAEEEGVTFEWLAAPRALSGEAEAVTGVRAIRMRLGAPDASGRQSPEEIPGGDFDRPAQLVVKAL
GFEPENLPEQWSAPDLKVTRWGTVKADVRNQMTNLDGVFAAGDIVRGASLVVWAIKDGRDAADAIHRYLLAKASSTLIAA
E

Sequences:

>Translated_481_residues
MAERMLKFTTVARKTPEKRAAAERSGDFHEIYADFIDAKATEQASRCSQCGVPFCQTHCPLHNNIPDWLRMTAEGRLEEA
YALSQATNSMPEVCGRICPQDRLCEGNCVIEQSGHGTVTIGSVERYLTDKAWEMGWVKPLAAGPARGQSVGIVGAGPAGL
AAAEKLREAGYDVTVYDRHDRAGGLLIYGIPGFKLEKDVVERRTQRLADGGVVFKLGFEVGKDATLEDLRAQHDAVLIAV
GVYAARDLTVPGGGSKGVVPALDYLITSNRLSLGDSVPAYDSGELNAEGKDVVVVGGGDTAMDCVRTAIRQGAKSVTCLY
RRDKANMPGSMREVANAEEEGVTFEWLAAPRALSGEAEAVTGVRAIRMRLGAPDASGRQSPEEIPGGDFDRPAQLVVKAL
GFEPENLPEQWSAPDLKVTRWGTVKADVRNQMTNLDGVFAAGDIVRGASLVVWAIKDGRDAADAIHRYLLAKASSTLIAA
E
>Mature_480_residues
AERMLKFTTVARKTPEKRAAAERSGDFHEIYADFIDAKATEQASRCSQCGVPFCQTHCPLHNNIPDWLRMTAEGRLEEAY
ALSQATNSMPEVCGRICPQDRLCEGNCVIEQSGHGTVTIGSVERYLTDKAWEMGWVKPLAAGPARGQSVGIVGAGPAGLA
AAEKLREAGYDVTVYDRHDRAGGLLIYGIPGFKLEKDVVERRTQRLADGGVVFKLGFEVGKDATLEDLRAQHDAVLIAVG
VYAARDLTVPGGGSKGVVPALDYLITSNRLSLGDSVPAYDSGELNAEGKDVVVVGGGDTAMDCVRTAIRQGAKSVTCLYR
RDKANMPGSMREVANAEEEGVTFEWLAAPRALSGEAEAVTGVRAIRMRLGAPDASGRQSPEEIPGGDFDRPAQLVVKALG
FEPENLPEQWSAPDLKVTRWGTVKADVRNQMTNLDGVFAAGDIVRGASLVVWAIKDGRDAADAIHRYLLAKASSTLIAAE

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=483, Percent_Identity=25.4658385093168, Blast_Score=155, Evalue=6e-38,
Organism=Escherichia coli, GI1789606, Length=475, Percent_Identity=46.1052631578947, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1788811, Length=471, Percent_Identity=46.7091295116773, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI87082180, Length=470, Percent_Identity=42.9787234042553, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1788468, Length=441, Percent_Identity=31.0657596371882, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1789243, Length=425, Percent_Identity=32.2352941176471, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17570289, Length=513, Percent_Identity=35.0877192982456, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71984108, Length=467, Percent_Identity=28.051391862955, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17543860, Length=161, Percent_Identity=31.055900621118, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320030, Length=494, Percent_Identity=34.8178137651822, Blast_Score=252, Evalue=8e-68,
Organism=Drosophila melanogaster, GI28574881, Length=491, Percent_Identity=38.0855397148676, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24665539, Length=491, Percent_Identity=38.0855397148676, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24665547, Length=491, Percent_Identity=38.0855397148676, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24665543, Length=491, Percent_Identity=38.0855397148676, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24640763, Length=464, Percent_Identity=27.5862068965517, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI18858217, Length=464, Percent_Identity=27.5862068965517, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 51544; Mature: 51413

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERMLKFTTVARKTPEKRAAAERSGDFHEIYADFIDAKATEQASRCSQCGVPFCQTHCP
CCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
LHNNIPDWLRMTAEGRLEEAYALSQATNSMPEVCGRICPQDRLCEGNCVIEQSGHGTVTI
CCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEE
GSVERYLTDKAWEMGWVKPLAAGPARGQSVGIVGAGPAGLAAAEKLREAGYDVTVYDRHD
CCHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCC
RAGGLLIYGIPGFKLEKDVVERRTQRLADGGVVFKLGFEVGKDATLEDLRAQHDAVLIAV
CCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEE
GVYAARDLTVPGGGSKGVVPALDYLITSNRLSLGDSVPAYDSGELNAEGKDVVVVGGGDT
EEHEECEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCH
AMDCVRTAIRQGAKSVTCLYRRDKANMPGSMREVANAEEEGVTFEWLAAPRALSGEAEAV
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCHHCCCEEEEECCCCCCCCCHHHH
TGVRAIRMRLGAPDASGRQSPEEIPGGDFDRPAQLVVKALGFEPENLPEQWSAPDLKVTR
HHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
WGTVKADVRNQMTNLDGVFAAGDIVRGASLVVWAIKDGRDAADAIHRYLLAKASSTLIAA
CCCCHHHHHHHHHCCCCEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEC
E
C
>Mature Secondary Structure 
AERMLKFTTVARKTPEKRAAAERSGDFHEIYADFIDAKATEQASRCSQCGVPFCQTHCP
CCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
LHNNIPDWLRMTAEGRLEEAYALSQATNSMPEVCGRICPQDRLCEGNCVIEQSGHGTVTI
CCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEE
GSVERYLTDKAWEMGWVKPLAAGPARGQSVGIVGAGPAGLAAAEKLREAGYDVTVYDRHD
CCHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCC
RAGGLLIYGIPGFKLEKDVVERRTQRLADGGVVFKLGFEVGKDATLEDLRAQHDAVLIAV
CCCCEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCEEEEEE
GVYAARDLTVPGGGSKGVVPALDYLITSNRLSLGDSVPAYDSGELNAEGKDVVVVGGGDT
EEHEECEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCH
AMDCVRTAIRQGAKSVTCLYRRDKANMPGSMREVANAEEEGVTFEWLAAPRALSGEAEAV
HHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCHHCCCEEEEECCCCCCCCCHHHH
TGVRAIRMRLGAPDASGRQSPEEIPGGDFDRPAQLVVKALGFEPENLPEQWSAPDLKVTR
HHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
WGTVKADVRNQMTNLDGVFAAGDIVRGASLVVWAIKDGRDAADAIHRYLLAKASSTLIAA
CCCCHHHHHHHHHCCCCEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428988; 2198943 [H]