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The map label for this gene is asd [H]

Identifier: 16127715

GI number: 16127715

Start: 3726918

End: 3727964

Strand: Direct

Name: asd [H]

Synonym: CC_3485

Alternate gene names: 16127715

Gene position: 3726918-3727964 (Clockwise)

Preceding gene: 16127714

Following gene: 16127716

Centisome position: 92.78

GC content: 71.25

Gene sequence:

>1047_bases
ATGAGCTTCAAGTTTTCCCGAGCCAATCCGCCCCATGTCGGCGTCGTCGGCGCCACCGGCCTGGTCGGCGGCATGATGCG
CGAGCTGCTGGTCGAGCGCGACTTCCCGGTCGCCTCCCTGCGCCTGTTCGCCTCGGCCCGTTCGGCGGGCGGCAAGATCG
ACTTCAACGGCCAGCAGATCGTCGTCGAGGACGCCGCCACCGCCGACTTCTCAGGGCTCGACATCGTGTTCTTCTCGGCC
GGCGGCTCTACCTCGCGCGAGCTGGCCCCCAAGGCCGCCGCCGCCGGCGCCGTGGTGATCGACAACAGCTCGGCCTGGCG
CTCGGACCCCGAGGTGCCGCTGGTGGTGGCGGAGGTCAATCCGCACGCCCTCCAGAACATCCCCAAGGGCATCGTCGCCA
ACCCCAACTGCACCACCATGGCCGCCATGCCGGTGCTCAAGCCCCTACACGACAAGGCGGGTCTGAAGCGCCTGACGGTC
AGCACCTACCAAGCCGCCTCGGGCGGCGGCATGGAGGGCATCGAGGTGCTGTCCGAGCAGCTGCGCGCCGGCGCGGCCGG
GGATCTGGACGGCCTGGCCCGTTCGCCGGACGCCGCCCCCCTGCCCGCGCCGCGCAAGTGGGCCGTGCCGCTGGCCTATA
ACGTGGTGCCGCTGAACTACGTGCTGGGCGAGGACGGCTATACCGAGGAAGAGCTGAAGCTGCGCGACGAGAGCCGCAAG
ATCCTCGAGATCCCCGGCCTGCCGGTCAGCGGCACCTGCGTGCGGGTGCCGGTCTTCACCGGTCACGCCCTGTCGATCAA
CGCCGAGTTCGACGGCCCGGTCTCGGTGGCCGAGGCGCTGGACCTGCTGGCCGCCGCGCCGGGCGTGGTCATCGACGACG
TCCCCAACCCGCTGGCCGCCACCGGCCAGGACCCGGTCTTTGTCGGCCGCGTGCGCCCCGACCCGACCGTTCCGCACGGC
CTGGCGCTGTTCGTCGTCGGCGACAACCTGCGCAAGGGCGCGGCCCTCAACGCCGTCCAGATCGCCGAGGTGATGCTGGG
GGCCTAA

Upstream 100 bases:

>100_bases
AGCGGCATCCTCGAACCAGCCCCGCCGATGCGCGGGGCGGCTCTCACATCCAGAGACCCAAAGCTCCCCGCGCTCCACAC
CCTCCCGGAGACGCAACACC

Downstream 100 bases:

>100_bases
AGACCAACAGCGCCCCCTCCGCCTCGCCGCTTCGCGCCAATTTCGCTCGCTCCACGGGCAGGGATCGATCGCCTCCTCCC
CCGCGCGCGGGAGAAGCGGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSFKFSRANPPHVGVVGATGLVGGMMRELLVERDFPVASLRLFASARSAGGKIDFNGQQIVVEDAATADFSGLDIVFFSA
GGSTSRELAPKAAAAGAVVIDNSSAWRSDPEVPLVVAEVNPHALQNIPKGIVANPNCTTMAAMPVLKPLHDKAGLKRLTV
STYQAASGGGMEGIEVLSEQLRAGAAGDLDGLARSPDAAPLPAPRKWAVPLAYNVVPLNYVLGEDGYTEEELKLRDESRK
ILEIPGLPVSGTCVRVPVFTGHALSINAEFDGPVSVAEALDLLAAAPGVVIDDVPNPLAATGQDPVFVGRVRPDPTVPHG
LALFVVGDNLRKGAALNAVQIAEVMLGA

Sequences:

>Translated_348_residues
MSFKFSRANPPHVGVVGATGLVGGMMRELLVERDFPVASLRLFASARSAGGKIDFNGQQIVVEDAATADFSGLDIVFFSA
GGSTSRELAPKAAAAGAVVIDNSSAWRSDPEVPLVVAEVNPHALQNIPKGIVANPNCTTMAAMPVLKPLHDKAGLKRLTV
STYQAASGGGMEGIEVLSEQLRAGAAGDLDGLARSPDAAPLPAPRKWAVPLAYNVVPLNYVLGEDGYTEEELKLRDESRK
ILEIPGLPVSGTCVRVPVFTGHALSINAEFDGPVSVAEALDLLAAAPGVVIDDVPNPLAATGQDPVFVGRVRPDPTVPHG
LALFVVGDNLRKGAALNAVQIAEVMLGA
>Mature_347_residues
SFKFSRANPPHVGVVGATGLVGGMMRELLVERDFPVASLRLFASARSAGGKIDFNGQQIVVEDAATADFSGLDIVFFSAG
GSTSRELAPKAAAAGAVVIDNSSAWRSDPEVPLVVAEVNPHALQNIPKGIVANPNCTTMAAMPVLKPLHDKAGLKRLTVS
TYQAASGGGMEGIEVLSEQLRAGAAGDLDGLARSPDAAPLPAPRKWAVPLAYNVVPLNYVLGEDGYTEEELKLRDESRKI
LEIPGLPVSGTCVRVPVFTGHALSINAEFDGPVSVAEALDLLAAAPGVVIDDVPNPLAATGQDPVFVGRVRPDPTVPHGL
ALFVVGDNLRKGAALNAVQIAEVMLGA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=340, Percent_Identity=35.2941176470588, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=29.9719887955182, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=394, Percent_Identity=28.1725888324873, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36072; Mature: 35940

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKFSRANPPHVGVVGATGLVGGMMRELLVERDFPVASLRLFASARSAGGKIDFNGQQI
CCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEE
VVEDAATADFSGLDIVFFSAGGSTSRELAPKAAAAGAVVIDNSSAWRSDPEVPLVVAEVN
EEECCCCCCCCCCEEEEEECCCCCCHHHCCHHHHCCEEEEECCCCCCCCCCCCEEEEECC
PHALQNIPKGIVANPNCTTMAAMPVLKPLHDKAGLKRLTVSTYQAASGGGMEGIEVLSEQ
CHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHH
LRAGAAGDLDGLARSPDAAPLPAPRKWAVPLAYNVVPLNYVLGEDGYTEEELKLRDESRK
HHCCCCCCCHHHCCCCCCCCCCCCCCEECEEEEEEEEEEEEECCCCCCHHHHHHHCCCCE
ILEIPGLPVSGTCVRVPVFTGHALSINAEFDGPVSVAEALDLLAAAPGVVIDDVPNPLAA
EEECCCCCCCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCC
TGQDPVFVGRVRPDPTVPHGLALFVVGDNLRKGAALNAVQIAEVMLGA
CCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SFKFSRANPPHVGVVGATGLVGGMMRELLVERDFPVASLRLFASARSAGGKIDFNGQQI
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEE
VVEDAATADFSGLDIVFFSAGGSTSRELAPKAAAAGAVVIDNSSAWRSDPEVPLVVAEVN
EEECCCCCCCCCCEEEEEECCCCCCHHHCCHHHHCCEEEEECCCCCCCCCCCCEEEEECC
PHALQNIPKGIVANPNCTTMAAMPVLKPLHDKAGLKRLTVSTYQAASGGGMEGIEVLSEQ
CHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHH
LRAGAAGDLDGLARSPDAAPLPAPRKWAVPLAYNVVPLNYVLGEDGYTEEELKLRDESRK
HHCCCCCCCHHHCCCCCCCCCCCCCCEECEEEEEEEEEEEEECCCCCCHHHHHHHCCCCE
ILEIPGLPVSGTCVRVPVFTGHALSINAEFDGPVSVAEALDLLAAAPGVVIDDVPNPLAA
EEECCCCCCCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCC
TGQDPVFVGRVRPDPTVPHGLALFVVGDNLRKGAALNAVQIAEVMLGA
CCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8936306 [H]