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The map label for this gene is trxB [H]

Identifier: 16127103

GI number: 16127103

Start: 3093832

End: 3094878

Strand: Direct

Name: trxB [H]

Synonym: CC_2871

Alternate gene names: 16127103

Gene position: 3093832-3094878 (Clockwise)

Preceding gene: 16127101

Following gene: 16127106

Centisome position: 77.02

GC content: 66.86

Gene sequence:

>1047_bases
ATGTCGCCACTGCGGAGAATCCACACTATATCTCCGCCCATGTCTACGCTCTCCCCTCGCCAGACCCGCTGCCTGATCAT
CGGATCGGGTCCCGCCGGCTACACCGCCGCCATCTACGCCGCGCGCGCGCTGCTGAAACCCGTGCTGATCGCCGGCATCC
AGCCCGGCGGCCAGCTGACCATCACGACCGATGTCGAGAACTATCCGGGCTTCGCCGACGTCATCCAGGGTCCCTGGCTG
ATGGACCAGATGCGCGCCCAGGCCGAGCATGTCGGCACCGAGTTCGTCAGCGACATCGTCACCAGCGTCGACCTGTCCAA
GCGTCCGTTCACGGTCAAGACCGACAGCGGCCAGGACTGGATCGCCGAGACGATCATCATCGCCACCGGCGCCCAGGCCA
AGTGGCTGGGCCTGGAAAGCGAAGCTAAGTTCCAGGGCTTTGGCGTCAGCGCCTGCGCCACCTGCGACGGCTTCTTCTAT
CGCAACAAGGACGTCATCGTGGTCGGCGGCGGCAACACCGCCGTGGAAGAGGCCCTGTTCCTGACCAGCTTCGCCAGCAA
GGTCACCCTGGTGCACCGCAAGGACGAGCTGCGCGCCGAGAAGATCCTGCAGGAGCGCCTGCTGGCCCATCCGAAGATCG
AGGTGATCTGGGACAGCGTCATCGACGAGGTCCTGGGCCAGACCGACCCCATGGGCGTCACCGGCGCGCGCCTGAAGAAC
GTCAAGACCGGCGAGACCCAAGAGGTCGCCGCCGACGGGGTGTTCATCGCCATCGGCCACGCGCCGTCGTCGGAGCTGTT
CGCCGGCCAGCTGGAAACCGGGTCCGGCGGCTATCTGAAGGTCAAGCCGGGCACGGCCTCGACGGCGATCGAGGGTGTCT
ACGCGGCCGGCGACGTCACCGACGACGTCTACCGCCAGGCCGTCACCGCCGCCGGCATGGGCTGCATGGCCGCCCTGGAA
GCCGTGCGCTTCCTCGCCGAAGAAGACCACAAGGCCGCCCACCATCCGATCAGCCACGCCGAGGCCAACAAGATCGGGGT
TTGGTGA

Upstream 100 bases:

>100_bases
GCACGTCGCCGAACCAGACATTGGCAAGGCCCGCGAACAGGGCGACGATACCCACGCCCAGTAGAACGCCGAGCTTCATC
AGGTTTTCCTCCCGTGGCTT

Downstream 100 bases:

>100_bases
GGGTTTAAGCCGCAAATCCTCCCCCTCGCGGGGGAGGTGTCGGCTCGAAGAGACGACGGAGGGGGAAGAGGCAGGGCCAG
CAGCACTTCCCCCTCCGGCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSPLRRIHTISPPMSTLSPRQTRCLIIGSGPAGYTAAIYAARALLKPVLIAGIQPGGQLTITTDVENYPGFADVIQGPWL
MDQMRAQAEHVGTEFVSDIVTSVDLSKRPFTVKTDSGQDWIAETIIIATGAQAKWLGLESEAKFQGFGVSACATCDGFFY
RNKDVIVVGGGNTAVEEALFLTSFASKVTLVHRKDELRAEKILQERLLAHPKIEVIWDSVIDEVLGQTDPMGVTGARLKN
VKTGETQEVAADGVFIAIGHAPSSELFAGQLETGSGGYLKVKPGTASTAIEGVYAAGDVTDDVYRQAVTAAGMGCMAALE
AVRFLAEEDHKAAHHPISHAEANKIGVW

Sequences:

>Translated_348_residues
MSPLRRIHTISPPMSTLSPRQTRCLIIGSGPAGYTAAIYAARALLKPVLIAGIQPGGQLTITTDVENYPGFADVIQGPWL
MDQMRAQAEHVGTEFVSDIVTSVDLSKRPFTVKTDSGQDWIAETIIIATGAQAKWLGLESEAKFQGFGVSACATCDGFFY
RNKDVIVVGGGNTAVEEALFLTSFASKVTLVHRKDELRAEKILQERLLAHPKIEVIWDSVIDEVLGQTDPMGVTGARLKN
VKTGETQEVAADGVFIAIGHAPSSELFAGQLETGSGGYLKVKPGTASTAIEGVYAAGDVTDDVYRQAVTAAGMGCMAALE
AVRFLAEEDHKAAHHPISHAEANKIGVW
>Mature_347_residues
SPLRRIHTISPPMSTLSPRQTRCLIIGSGPAGYTAAIYAARALLKPVLIAGIQPGGQLTITTDVENYPGFADVIQGPWLM
DQMRAQAEHVGTEFVSDIVTSVDLSKRPFTVKTDSGQDWIAETIIIATGAQAKWLGLESEAKFQGFGVSACATCDGFFYR
NKDVIVVGGGNTAVEEALFLTSFASKVTLVHRKDELRAEKILQERLLAHPKIEVIWDSVIDEVLGQTDPMGVTGARLKNV
KTGETQEVAADGVFIAIGHAPSSELFAGQLETGSGGYLKVKPGTASTAIEGVYAAGDVTDDVYRQAVTAAGMGCMAALEA
VRFLAEEDHKAAHHPISHAEANKIGVW

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=316, Percent_Identity=52.5316455696203, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=33.5483870967742, Blast_Score=134, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=46.6666666666667, Blast_Score=284, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=44.794952681388, Blast_Score=275, Evalue=8e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 37093; Mature: 36961

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLRRIHTISPPMSTLSPRQTRCLIIGSGPAGYTAAIYAARALLKPVLIAGIQPGGQLT
CCCHHHHEECCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
ITTDVENYPGFADVIQGPWLMDQMRAQAEHVGTEFVSDIVTSVDLSKRPFTVKTDSGQDW
EEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCH
IAETIIIATGAQAKWLGLESEAKFQGFGVSACATCDGFFYRNKDVIVVGGGNTAVEEALF
HEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHCCCEEEECCCEEEECCCCHHHHHHHH
LTSFASKVTLVHRKDELRAEKILQERLLAHPKIEVIWDSVIDEVLGQTDPMGVTGARLKN
HHHHHHHEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCC
VKTGETQEVAADGVFIAIGHAPSSELFAGQLETGSGGYLKVKPGTASTAIEGVYAAGDVT
CCCCCCHHHCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCHHHCCEEECCCCC
DDVYRQAVTAAGMGCMAALEAVRFLAEEDHKAAHHPISHAEANKIGVW
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPLRRIHTISPPMSTLSPRQTRCLIIGSGPAGYTAAIYAARALLKPVLIAGIQPGGQLT
CCHHHHEECCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEE
ITTDVENYPGFADVIQGPWLMDQMRAQAEHVGTEFVSDIVTSVDLSKRPFTVKTDSGQDW
EEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCH
IAETIIIATGAQAKWLGLESEAKFQGFGVSACATCDGFFYRNKDVIVVGGGNTAVEEALF
HEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHCCCEEEECCCEEEECCCCHHHHHHHH
LTSFASKVTLVHRKDELRAEKILQERLLAHPKIEVIWDSVIDEVLGQTDPMGVTGARLKN
HHHHHHHEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCC
VKTGETQEVAADGVFIAIGHAPSSELFAGQLETGSGGYLKVKPGTASTAIEGVYAAGDVT
CCCCCCHHHCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCCHHHCCEEECCCCC
DDVYRQAVTAAGMGCMAALEAVRFLAEEDHKAAHHPISHAEANKIGVW
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA