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The map label for this gene is exuR [H]

Identifier: 16127045

GI number: 16127045

Start: 3034329

End: 3035078

Strand: Direct

Name: exuR [H]

Synonym: CC_2813

Alternate gene names: 16127045

Gene position: 3034329-3035078 (Clockwise)

Preceding gene: 16127044

Following gene: 16127046

Centisome position: 75.54

GC content: 70.93

Gene sequence:

>750_bases
ATGTCTGACAACGTCAAGCTCTACCGTAAGATCGCCGACTCCGTGGCCGACGACATCGAGGCCGGGCGCTACAGGCTGGG
CGACCGCCTGCCGACCGAACGGGAGCTGGCCGAGCAGTTCGGGGTGTCCCGCCCCACCCTGCGCGAGGCGATGATCGCGC
TGGAGATGCTAGGCATGATCGAGGCCCGCCACGGCCTGGGCATCTATGTCACGGCGACCGCGCGCCCCCTCGCGCCGTCG
CCGGAGATCGACTTCGAGATCGGCGCCTTCGAGCTGATCGAGGCCCGCCGCCTGTTCGAGGGCGAGGCCGCCGCCCTGGC
CGCCACCTCGATCACCGACGAGCAGATCGCGGCGCTGGAAGGCCTGCTGACCCGCATGCACGAGGAAGAGGAAATCCGGG
GCGAGGACGCCGACCGCGAGTTCCACCTGACCATCGCCCGGGCCACCGGCAATGGCGCGATCATCGCCACGATCGAGACC
CTGTGGGACTGGCGCAACCGCTCGCCGCTCGCCCGCAACATCCTGGCCCGCGCCCGCGGCATGGGCCTGGAGCCCCGCAT
CGCCGAGCACCGCCGCGTCGTCGACGCCCTCAAGGCCCGCGACCCCGCCGCCGCCCGCCAGGCCATGCGCGACCACCTGG
AACGCGTCATCGACCACCTGCTGCACGCCACCGAAACCGAAGCCGTCCAGCGCGCCCAGGAAGAAACCAACGCCCGCCGC
AGCGCCCTGGCGAAACGGGTGGCGATTTAA

Upstream 100 bases:

>100_bases
GCGCGAAAAATGAGGCTCATCGGCGCGGTTGGCCGTGATAGAGATTGGCGCTTTCCCCCGCCCTGGGGCGTGTTTCTGCG
CCTGCTCAAGCCCGATCGCC

Downstream 100 bases:

>100_bases
AATCCCTCTCTCTTTGAGAGAGGGAGGGGCCCATCGCGCAGCGATGGGAGGGTGAGTGGTCAAGCCCTCGCCAGAAATCC
CGATTCCTGTCGTTGCATTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSDNVKLYRKIADSVADDIEAGRYRLGDRLPTERELAEQFGVSRPTLREAMIALEMLGMIEARHGLGIYVTATARPLAPS
PEIDFEIGAFELIEARRLFEGEAAALAATSITDEQIAALEGLLTRMHEEEEIRGEDADREFHLTIARATGNGAIIATIET
LWDWRNRSPLARNILARARGMGLEPRIAEHRRVVDALKARDPAAARQAMRDHLERVIDHLLHATETEAVQRAQEETNARR
SALAKRVAI

Sequences:

>Translated_249_residues
MSDNVKLYRKIADSVADDIEAGRYRLGDRLPTERELAEQFGVSRPTLREAMIALEMLGMIEARHGLGIYVTATARPLAPS
PEIDFEIGAFELIEARRLFEGEAAALAATSITDEQIAALEGLLTRMHEEEEIRGEDADREFHLTIARATGNGAIIATIET
LWDWRNRSPLARNILARARGMGLEPRIAEHRRVVDALKARDPAAARQAMRDHLERVIDHLLHATETEAVQRAQEETNARR
SALAKRVAI
>Mature_248_residues
SDNVKLYRKIADSVADDIEAGRYRLGDRLPTERELAEQFGVSRPTLREAMIALEMLGMIEARHGLGIYVTATARPLAPSP
EIDFEIGAFELIEARRLFEGEAAALAATSITDEQIAALEGLLTRMHEEEEIRGEDADREFHLTIARATGNGAIIATIETL
WDWRNRSPLARNILARARGMGLEPRIAEHRRVVDALKARDPAAARQAMRDHLERVIDHLLHATETEAVQRAQEETNARRS
ALAKRVAI

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=247, Percent_Identity=32.7935222672065, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790780, Length=238, Percent_Identity=33.1932773109244, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789353, Length=237, Percent_Identity=32.0675105485232, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790032, Length=238, Percent_Identity=31.9327731092437, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789621, Length=216, Percent_Identity=30.0925925925926, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27802; Mature: 27671

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNVKLYRKIADSVADDIEAGRYRLGDRLPTERELAEQFGVSRPTLREAMIALEMLGMI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EARHGLGIYVTATARPLAPSPEIDFEIGAFELIEARRLFEGEAAALAATSITDEQIAALE
HHCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH
GLLTRMHEEEEIRGEDADREFHLTIARATGNGAIIATIETLWDWRNRSPLARNILARARG
HHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHC
MGLEPRIAEHRRVVDALKARDPAAARQAMRDHLERVIDHLLHATETEAVQRAQEETNARR
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALAKRVAI
HHHHHHHCC
>Mature Secondary Structure 
SDNVKLYRKIADSVADDIEAGRYRLGDRLPTERELAEQFGVSRPTLREAMIALEMLGMI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EARHGLGIYVTATARPLAPSPEIDFEIGAFELIEARRLFEGEAAALAATSITDEQIAALE
HHCCCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHH
GLLTRMHEEEEIRGEDADREFHLTIARATGNGAIIATIETLWDWRNRSPLARNILARARG
HHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEHHHHHCCCCCCHHHHHHHHHHHC
MGLEPRIAEHRRVVDALKARDPAAARQAMRDHLERVIDHLLHATETEAVQRAQEETNARR
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALAKRVAI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA