BacMap

Definition	Caulobacter crescentus CB15 chromosome, complete genome.
Accession	NC_002696
Length	4,016,947

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The map label for this gene is gra-orf6 [H]

Identifier: 16126890

GI number: 16126890

Start: 2873035

End: 2873838

Strand: Direct

Name: gra-orf6 [H]

Synonym: CC_2655

Alternate gene names: 16126890

Gene position: 2873035-2873838 (Clockwise)

Preceding gene: 16126888

Following gene: 16126893

Centisome position: 71.52

GC content: 69.53

Gene sequence:

>804_bases
ATGTTGGGACGGGACTTCGAAGGGTTCACCGTGGTGGTCACCGGCGGCTCCACGGGGCTGGGTCGGGCGATCGCCGTGGA
GACCGCCCGGCGCGGCGCGGGCCTTGTCGTGATCAACTTCGCCCGCAGCGCCGAGGAAGCCGAAGAGACCGCAAGGCTCG
TCCAGGCCGAGGGCGCCAAGGCGGTTTTGGCGCAGGGCGACGTGTCCAGCGACGAGGATTGCCGCAGGATCGCGGCCGCC
GCCGACGCCTCGGGCCGCATCGATGCGCTGTTCAACAACGCCGGCATGACCAAGTTCGCGCCGAACCACGCTGATCTCGA
CGCCGTCAACGCCGAGGATTTCCTGCGGCTCTATTCGGTGAACGTCGTCGGCGCCTTCCAGATGGTCCGCGCCGCCCGCA
CGCTGCTGGAGGCCGCGCCGTCACCCGGCGCCGTGGTCAACACCTCTTCGATCGCGGGCGTGGTCGGCAACGGCTCATCG
GTGCCCTACGCCGCCTCCAAGGGCGCGATGACCACGATGACGTTGTCGCTGGCCCGCGCGCTTGCGCCGCGCATTCGCGT
CAACGCCGTCTGCCCGGGCTTCATCGACACACCGTGGTTCGAAAAGGCCATGGACGCCGAGCGAATCGATCGTCTTCGCG
CCGGCGCGGCTGCGGCGACACCGTTGAAGGTCGCCTCCACCGCCGAAGACATCGCCGGCGCGGCCGTCTTTCTGGCGTCC
CCTGCGTCGCGGCATGTCACCGGCGAGACCCTGTTGGTCGACGGGGGGCTCCACCTCGGCGGCGCAAGCCTTTCCATGCG
GTAA

Upstream 100 bases:

>100_bases
TTCAGATCGGTCATCGGCGCGATTTAGGCCTCCGCGCCTCCCGAGACAAGCGCGCGGCGCCCCGCTACAAGGTCGCAAAC
AGATGTTCGGGAGAGACGCG

Downstream 100 bases:

>100_bases
AGACACAGCCAAGCTGGATTCGCTTTTCAGGCGCATGTGACCAAGCAGCGCCTGGATTGCAGCAAAATCGTCACACATGT
ACGTCGTCAGAAGTTTTGAG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLGRDFEGFTVVVTGGSTGLGRAIAVETARRGAGLVVINFARSAEEAEETARLVQAEGAKAVLAQGDVSSDEDCRRIAAA
ADASGRIDALFNNAGMTKFAPNHADLDAVNAEDFLRLYSVNVVGAFQMVRAARTLLEAAPSPGAVVNTSSIAGVVGNGSS
VPYAASKGAMTTMTLSLARALAPRIRVNAVCPGFIDTPWFEKAMDAERIDRLRAGAAAATPLKVASTAEDIAGAAVFLAS
PASRHVTGETLLVDGGLHLGGASLSMR

Sequences:

>Translated_267_residues
MLGRDFEGFTVVVTGGSTGLGRAIAVETARRGAGLVVINFARSAEEAEETARLVQAEGAKAVLAQGDVSSDEDCRRIAAA
ADASGRIDALFNNAGMTKFAPNHADLDAVNAEDFLRLYSVNVVGAFQMVRAARTLLEAAPSPGAVVNTSSIAGVVGNGSS
VPYAASKGAMTTMTLSLARALAPRIRVNAVCPGFIDTPWFEKAMDAERIDRLRAGAAAATPLKVASTAEDIAGAAVFLAS
PASRHVTGETLLVDGGLHLGGASLSMR
>Mature_267_residues
MLGRDFEGFTVVVTGGSTGLGRAIAVETARRGAGLVVINFARSAEEAEETARLVQAEGAKAVLAQGDVSSDEDCRRIAAA
ADASGRIDALFNNAGMTKFAPNHADLDAVNAEDFLRLYSVNVVGAFQMVRAARTLLEAAPSPGAVVNTSSIAGVVGNGSS
VPYAASKGAMTTMTLSLARALAPRIRVNAVCPGFIDTPWFEKAMDAERIDRLRAGAAAATPLKVASTAEDIAGAAVFLAS
PASRHVTGETLLVDGGLHLGGASLSMR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=221, Percent_Identity=34.3891402714932, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=32.1705426356589, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=33.2, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=32.5396825396825, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI83715985, Length=264, Percent_Identity=28.7878787878788, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI19923817, Length=265, Percent_Identity=26.0377358490566, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=269, Percent_Identity=29.7397769516729, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=32.1285140562249, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=29.1828793774319, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI225579078, Length=207, Percent_Identity=29.951690821256, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=31.5, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=29.8850574712644, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=36.4, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=35.6589147286822, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=33.0677290836653, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=30.5882352941176, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=30.9433962264151, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=32.4324324324324, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=29.0076335877863, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=33.2046332046332, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.8482490272374, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=29.3877551020408, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=39.1129032258064, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.0677290836653, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=33.59375, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=32.4723247232472, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=268, Percent_Identity=30.2238805970149, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=32.3529411764706, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.9411764705882, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=31.5985130111524, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=33.7254901960784, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=30.6273062730627, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=30.2583025830258, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=29.718875502008, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=30, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.4511278195489, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=31.0606060606061, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=274, Percent_Identity=29.9270072992701, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=31.203007518797, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=29.520295202952, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.188679245283, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=200, Percent_Identity=28.5, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=30.5019305019305, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=206, Percent_Identity=30.5825242718447, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=30.5147058823529, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=30.3370786516854, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=30.3921568627451, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=208, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=29.3814432989691, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=251, Percent_Identity=29.4820717131474, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=271, Percent_Identity=28.4132841328413, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=34.2412451361868, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=32.295719844358, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32.4, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17737361, Length=261, Percent_Identity=31.8007662835249, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=29.3436293436293, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=31.1284046692607, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580925, Length=209, Percent_Identity=31.1004784688995, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=30.5019305019305, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27358; Mature: 27358

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGRDFEGFTVVVTGGSTGLGRAIAVETARRGAGLVVINFARSAEEAEETARLVQAEGAK
CCCCCCCCEEEEEECCCCCCCCEEEEEHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCE
AVLAQGDVSSDEDCRRIAAAADASGRIDALFNNAGMTKFAPNHADLDAVNAEDFLRLYSV
EEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHH
NVVGAFQMVRAARTLLEAAPSPGAVVNTSSIAGVVGNGSSVPYAASKGAMTTMTLSLARA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LAPRIRVNAVCPGFIDTPWFEKAMDAERIDRLRAGAAAATPLKVASTAEDIAGAAVFLAS
HCCCEEEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHHCCEEEEEEC
PASRHVTGETLLVDGGLHLGGASLSMR
CCCCCCCCCEEEEECCCEECCCCCCCC
>Mature Secondary Structure
MLGRDFEGFTVVVTGGSTGLGRAIAVETARRGAGLVVINFARSAEEAEETARLVQAEGAK
CCCCCCCCEEEEEECCCCCCCCEEEEEHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCE
AVLAQGDVSSDEDCRRIAAAADASGRIDALFNNAGMTKFAPNHADLDAVNAEDFLRLYSV
EEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHH
NVVGAFQMVRAARTLLEAAPSPGAVVNTSSIAGVVGNGSSVPYAASKGAMTTMTLSLARA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LAPRIRVNAVCPGFIDTPWFEKAMDAERIDRLRAGAAAATPLKVASTAEDIAGAAVFLAS
HCCCEEEEEECCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCEEHHHHHHHHCCEEEEEEC
PASRHVTGETLLVDGGLHLGGASLSMR
CCCCCCCCCEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]