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The map label for this gene is pucG [H]

Identifier: 16126841

GI number: 16126841

Start: 2814494

End: 2815672

Strand: Direct

Name: pucG [H]

Synonym: CC_2604

Alternate gene names: 16126841

Gene position: 2814494-2815672 (Clockwise)

Preceding gene: 16126840

Following gene: 16126842

Centisome position: 70.07

GC content: 69.3

Gene sequence:

>1179_bases
ATGGGCCCCGGCCCGATCAACGTGCATCCGCGCGTGCTGCGGGCGATGTCGGTGCAGCTCTTGGGCCAGTTCGACCCCGA
GTTCACCGGTTACATGAACGAGGTGATGGCCCTCTATCGCGGCGTCTTCCAGACCCAGAACCGCTGGACCTTCACGATCG
ACGGCACCTCGCGCGCCGGCATCGAGGCGGCGCTGGTCTCGACCCTTCAGCCCGGCGACGACGTCGTGGTGGTCAATGCC
GGGCGCTTTGGCCTGCTGCTGGCCGAGATCGCCGAGCGCTGCGACGCCAAGGTCACCTTCGTCGAGGCGTCGTGGGGCGC
CGTGGTCGATCCGCAGGCGGTCGAGGATGCGGTCAAGCGCGTCAAGCCGCGCCTGGTCGCCTGCGTCCACGGCGACACCT
CGACCACCATGGCCCAGCCGCTGGGAGAGATCGGCGCGATCTGCCGCGCGCACGGGGCGCTGATGTATGTCGACGCCACC
GCCACCCTGTCGGGCATGGACGTTCCCGTCGACGCCTGGGGCGCCGACATTGTCACCGCCGGCCTGCAGAAGTGCCTGGG
CGGTCCCTCCGGCTCGGCCCCGATCACGATCAGCGACCAGGCCGCCGAGCACATCTTCTCGCGTCGTCACGTCGAGAAGG
GTCTGGCCGGAACCGGCGGCGCGGCGGGCGCCGGCCGGCGCATCGCCTCCAACTACTTCGATCTGGCGATGATCATGGAC
TACTGGTCCGAAAAGCGCCTGAACCACCACACCGAGTGCGCGCCGATGCTGTTCGCCGCTCGCGAATGCGCGCGGCTGGT
GCTGGAGGAAGGCCTGCCGGCGCGCTTCGACCGCCACGCCCAGGCGGGCGCGGCCATGACCGCCGGGCTCGAAGCGATGG
GCCTCTCCATCTACGGCGACAAGGCTCACAAGATGACCAATGTCACCGGTATCTGGGTCCCGAAAGGCGTCGACTACGAC
CGCGTGAAGGCGCGGATGCGCACCGACTTCGAGATCGAGATCGGCTCAGCCTTCGGTCCCCTGACCGGCAAGATCTGGCG
CATCGGGACCATGGGCGTGAACGCCCGCAAGCACGCGGTGCTGCAGACGCTCGCGGCCTTCGAGGCGGTGCTGCGCTGGG
AGGGCTTCAGCGCTCCGGCCGGCGCGGGGGTGGATGCGGCGGCGAAGGTGTACGGATGA

Upstream 100 bases:

>100_bases
GCGCGCCGCAGGCGGGCCTCGAAGGACGCACAGTGACCACCGCCAAGACCATGCCATGACCGACACCTTCAACGAACTCG
ACCACCCCGCCCGCCTGCTG

Downstream 100 bases:

>100_bases
GGGCGTCGTTCAAAATCCTCCCCCCAGCGGGGGAGGTGTCGGCGCAGCGGACGGAGGGGGAAGTTCTGCTGCCCCTTCCC
CTTCCCCCTCCGGCGCTTCG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MGPGPINVHPRVLRAMSVQLLGQFDPEFTGYMNEVMALYRGVFQTQNRWTFTIDGTSRAGIEAALVSTLQPGDDVVVVNA
GRFGLLLAEIAERCDAKVTFVEASWGAVVDPQAVEDAVKRVKPRLVACVHGDTSTTMAQPLGEIGAICRAHGALMYVDAT
ATLSGMDVPVDAWGADIVTAGLQKCLGGPSGSAPITISDQAAEHIFSRRHVEKGLAGTGGAAGAGRRIASNYFDLAMIMD
YWSEKRLNHHTECAPMLFAARECARLVLEEGLPARFDRHAQAGAAMTAGLEAMGLSIYGDKAHKMTNVTGIWVPKGVDYD
RVKARMRTDFEIEIGSAFGPLTGKIWRIGTMGVNARKHAVLQTLAAFEAVLRWEGFSAPAGAGVDAAAKVYG

Sequences:

>Translated_392_residues
MGPGPINVHPRVLRAMSVQLLGQFDPEFTGYMNEVMALYRGVFQTQNRWTFTIDGTSRAGIEAALVSTLQPGDDVVVVNA
GRFGLLLAEIAERCDAKVTFVEASWGAVVDPQAVEDAVKRVKPRLVACVHGDTSTTMAQPLGEIGAICRAHGALMYVDAT
ATLSGMDVPVDAWGADIVTAGLQKCLGGPSGSAPITISDQAAEHIFSRRHVEKGLAGTGGAAGAGRRIASNYFDLAMIMD
YWSEKRLNHHTECAPMLFAARECARLVLEEGLPARFDRHAQAGAAMTAGLEAMGLSIYGDKAHKMTNVTGIWVPKGVDYD
RVKARMRTDFEIEIGSAFGPLTGKIWRIGTMGVNARKHAVLQTLAAFEAVLRWEGFSAPAGAGVDAAAKVYG
>Mature_391_residues
GPGPINVHPRVLRAMSVQLLGQFDPEFTGYMNEVMALYRGVFQTQNRWTFTIDGTSRAGIEAALVSTLQPGDDVVVVNAG
RFGLLLAEIAERCDAKVTFVEASWGAVVDPQAVEDAVKRVKPRLVACVHGDTSTTMAQPLGEIGAICRAHGALMYVDATA
TLSGMDVPVDAWGADIVTAGLQKCLGGPSGSAPITISDQAAEHIFSRRHVEKGLAGTGGAAGAGRRIASNYFDLAMIMDY
WSEKRLNHHTECAPMLFAARECARLVLEEGLPARFDRHAQAGAAMTAGLEAMGLSIYGDKAHKMTNVTGIWVPKGVDYDR
VKARMRTDFEIEIGSAFGPLTGKIWRIGTMGVNARKHAVLQTLAAFEAVLRWEGFSAPAGAGVDAAAKVYG

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=376, Percent_Identity=32.9787234042553, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17536281, Length=364, Percent_Identity=35.4395604395604, Blast_Score=219, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321079, Length=373, Percent_Identity=24.1286863270777, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17530823, Length=377, Percent_Identity=32.3607427055703, Blast_Score=200, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41804; Mature: 41673

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPGPINVHPRVLRAMSVQLLGQFDPEFTGYMNEVMALYRGVFQTQNRWTFTIDGTSRAG
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
IEAALVSTLQPGDDVVVVNAGRFGLLLAEIAERCDAKVTFVEASWGAVVDPQAVEDAVKR
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHH
VKPRLVACVHGDTSTTMAQPLGEIGAICRAHGALMYVDATATLSGMDVPVDAWGADIVTA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCHHHCCHHHHHH
GLQKCLGGPSGSAPITISDQAAEHIFSRRHVEKGLAGTGGAAGAGRRIASNYFDLAMIMD
HHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
YWSEKRLNHHTECAPMLFAARECARLVLEEGLPARFDRHAQAGAAMTAGLEAMGLSIYGD
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHCHHHHCEEEECC
KAHKMTNVTGIWVPKGVDYDRVKARMRTDFEIEIGSAFGPLTGKIWRIGTMGVNARKHAV
CHHHHCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHH
LQTLAAFEAVLRWEGFSAPAGAGVDAAAKVYG
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
GPGPINVHPRVLRAMSVQLLGQFDPEFTGYMNEVMALYRGVFQTQNRWTFTIDGTSRAG
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
IEAALVSTLQPGDDVVVVNAGRFGLLLAEIAERCDAKVTFVEASWGAVVDPQAVEDAVKR
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHH
VKPRLVACVHGDTSTTMAQPLGEIGAICRAHGALMYVDATATLSGMDVPVDAWGADIVTA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCCHHHCCHHHHHH
GLQKCLGGPSGSAPITISDQAAEHIFSRRHVEKGLAGTGGAAGAGRRIASNYFDLAMIMD
HHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
YWSEKRLNHHTECAPMLFAARECARLVLEEGLPARFDRHAQAGAAMTAGLEAMGLSIYGD
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHCHHHHCEEEECC
KAHKMTNVTGIWVPKGVDYDRVKARMRTDFEIEIGSAFGPLTGKIWRIGTMGVNARKHAV
CHHHHCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHH
LQTLAAFEAVLRWEGFSAPAGAGVDAAAKVYG
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]