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The map label for this gene is fadL [H]

Identifier: 16126333

GI number: 16126333

Start: 2304161

End: 2305459

Strand: Direct

Name: fadL [H]

Synonym: CC_2094

Alternate gene names: 16126333

Gene position: 2304161-2305459 (Clockwise)

Preceding gene: 16126332

Following gene: 16126337

Centisome position: 57.36

GC content: 68.28

Gene sequence:

>1299_bases
ATGTCTCTTACGCGTACCCGCCTCGCCGTCGGCGTGGCTTTCGTGGCGCTCGTCGCCGCCTCCCAGGCCTCCGCTTCGGC
CTTCTATCTGCAGGAACAATCGGTTCGCGGCACGGGCCGCGCCTATTCGGGCGAAGTCGCCGACAAGGGCGTCGGCAGCC
TGTGGTGGAACCCGGCGTCGATCGCCGGCATCGCCCGCAGCGAAGCCCACTTCGGCCTGAACCAGATCCTGGTGAACTCC
GAGGTCACCAACACCGGCTCCAGCATCACCCGCCCGGTCCCCCCGGCCGGCCTGACCACTGCGGTCGGCGGCGCCGACGC
CGCCTTCGACCCGATCAACAACGGCATCGTGCCGAACTTCGGCGCCGCCTGGAAGATCAACGACAAGCTCTCGCTGGGCC
TGTCGGTCGCCGCGCCCTACAACTTCACCACCGAGTACACCGCCAACAGCTGGACCCGCTACGACGCGCTGAAGTCGCAG
CTGCGGACCGTCAATGTCGAGGGCGTGGTCGCCTATCGCGTCAATGACATGCTGGACCTGGGCCTTGGCGTGACGGCGAT
GTACGCCGACGCCGAACTGACCAACGCCCTGCCCAACATCTCGCCGCTGCAAGCCGATGGCCTGCAATCGCTGAAGGGTG
ACGGCTTCGCCTATGGCTACAGCGTCGGCGCGCAACTGCACCCGTCCAAGAGCCTGACGATCGGCGCCAGCTATCGCAGC
AAACTCGACCACAAGCTGGACGGCACGGTGAAGGTCTCGGGCCTGCTGGCTCCGATCCCCGCCGCCAGCAACTTCACGGT
CGACGGCCAGGCCAAGATCACCCTGCCCTGGATCGCCAACCTCGGCGCGCGCTGGGCGGTGAATGACCAGTGGACCCTGA
ACGGTTCGGTCAGCCGCGTGGGCTGGAGCGAGTTCGACGCCATCCGCGTCAGCTTCGCCGGCGGCGGCTCGACCAGCCCC
CAGGACTATAAGGACGTCACCACCTACGCGGCCGGCGTCGACTACCAGGCCTCGCCTCGTCTGACGCTGCGGGCCGGCGT
CCAGTATGACCCGACCCCGACCCCGGAGATCGGCCGCACCGCCCGCGTGCCGGACGGCGACCGCATGATGTACGCCACCG
GCGCGACCTGGGCTGCGACCGAGACCCTGCAGCTCGACGCCGCGATCAGCTACATCGCGTTCGACAAGAGCCAGATCAAT
CGCACCGACGTCACCGCCACCAGCTCGACCGTCCGCCTGCGCGGCGATGTCGAGGGTTCGGCCGTCGTGCTCGCGGCCGG
CGCGCGCTTCAGCTTCTAA

Upstream 100 bases:

>100_bases
TATCAACGCTATTTGACTGAATGGGTTACAGGCGGCGCTCCTCGAGCGCCAACCGGCGCCCGGCGGACCTCCTCCTCCCC
AAGAAGGTCGCTAGTCAAAG

Downstream 100 bases:

>100_bases
GGCTGAGCCAGCGTTGAGATACTGGGCCATCCGGGGAAACCTGGATGGCCCTTTTCGCATCTAAACTCATGTGTCATCCC
GGCCGTAGCGAAGCGCAGAG

Product: outer membrane protein

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSLTRTRLAVGVAFVALVAASQASASAFYLQEQSVRGTGRAYSGEVADKGVGSLWWNPASIAGIARSEAHFGLNQILVNS
EVTNTGSSITRPVPPAGLTTAVGGADAAFDPINNGIVPNFGAAWKINDKLSLGLSVAAPYNFTTEYTANSWTRYDALKSQ
LRTVNVEGVVAYRVNDMLDLGLGVTAMYADAELTNALPNISPLQADGLQSLKGDGFAYGYSVGAQLHPSKSLTIGASYRS
KLDHKLDGTVKVSGLLAPIPAASNFTVDGQAKITLPWIANLGARWAVNDQWTLNGSVSRVGWSEFDAIRVSFAGGGSTSP
QDYKDVTTYAAGVDYQASPRLTLRAGVQYDPTPTPEIGRTARVPDGDRMMYATGATWAATETLQLDAAISYIAFDKSQIN
RTDVTATSSTVRLRGDVEGSAVVLAAGARFSF

Sequences:

>Translated_432_residues
MSLTRTRLAVGVAFVALVAASQASASAFYLQEQSVRGTGRAYSGEVADKGVGSLWWNPASIAGIARSEAHFGLNQILVNS
EVTNTGSSITRPVPPAGLTTAVGGADAAFDPINNGIVPNFGAAWKINDKLSLGLSVAAPYNFTTEYTANSWTRYDALKSQ
LRTVNVEGVVAYRVNDMLDLGLGVTAMYADAELTNALPNISPLQADGLQSLKGDGFAYGYSVGAQLHPSKSLTIGASYRS
KLDHKLDGTVKVSGLLAPIPAASNFTVDGQAKITLPWIANLGARWAVNDQWTLNGSVSRVGWSEFDAIRVSFAGGGSTSP
QDYKDVTTYAAGVDYQASPRLTLRAGVQYDPTPTPEIGRTARVPDGDRMMYATGATWAATETLQLDAAISYIAFDKSQIN
RTDVTATSSTVRLRGDVEGSAVVLAAGARFSF
>Mature_431_residues
SLTRTRLAVGVAFVALVAASQASASAFYLQEQSVRGTGRAYSGEVADKGVGSLWWNPASIAGIARSEAHFGLNQILVNSE
VTNTGSSITRPVPPAGLTTAVGGADAAFDPINNGIVPNFGAAWKINDKLSLGLSVAAPYNFTTEYTANSWTRYDALKSQL
RTVNVEGVVAYRVNDMLDLGLGVTAMYADAELTNALPNISPLQADGLQSLKGDGFAYGYSVGAQLHPSKSLTIGASYRSK
LDHKLDGTVKVSGLLAPIPAASNFTVDGQAKITLPWIANLGARWAVNDQWTLNGSVSRVGWSEFDAIRVSFAGGGSTSPQ
DYKDVTTYAAGVDYQASPRLTLRAGVQYDPTPTPEIGRTARVPDGDRMMYATGATWAATETLQLDAAISYIAFDKSQINR
TDVTATSSTVRLRGDVEGSAVVLAAGARFSF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=439, Percent_Identity=26.879271070615, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 45510; Mature: 45379

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTRTRLAVGVAFVALVAASQASASAFYLQEQSVRGTGRAYSGEVADKGVGSLWWNPAS
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IAGIARSEAHFGLNQILVNSEVTNTGSSITRPVPPAGLTTAVGGADAAFDPINNGIVPNF
HHHEECCHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GAAWKINDKLSLGLSVAAPYNFTTEYTANSWTRYDALKSQLRTVNVEGVVAYRVNDMLDL
CCEEEECCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHEEECCCEEEEEEECCHHHC
GLGVTAMYADAELTNALPNISPLQADGLQSLKGDGFAYGYSVGAQLHPSKSLTIGASYRS
CCCEEEEEECCHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCEECCCCCEEEECHHHH
KLDHKLDGTVKVSGLLAPIPAASNFTVDGQAKITLPWIANLGARWAVNDQWTLNGSVSRV
HCCCCCCCEEEEEEEEECCCCCCCEEECCCEEEEEEEHHCCCCEEECCCEEEECCCCEEC
GWSEFDAIRVSFAGGGSTSPQDYKDVTTYAAGVDYQASPRLTLRAGVQYDPTPTPEIGRT
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCEECCCCCCCCCCC
ARVPDGDRMMYATGATWAATETLQLDAAISYIAFDKSQINRTDVTATSSTVRLRGDVEGS
CCCCCCCEEEEEECCCEEEEEEEEECCEEEEEEECHHHCCCCEEEECCCEEEEEECCCCC
AVVLAAGARFSF
EEEEEECCCCCC
>Mature Secondary Structure 
SLTRTRLAVGVAFVALVAASQASASAFYLQEQSVRGTGRAYSGEVADKGVGSLWWNPAS
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IAGIARSEAHFGLNQILVNSEVTNTGSSITRPVPPAGLTTAVGGADAAFDPINNGIVPNF
HHHEECCHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
GAAWKINDKLSLGLSVAAPYNFTTEYTANSWTRYDALKSQLRTVNVEGVVAYRVNDMLDL
CCEEEECCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHEEECCCEEEEEEECCHHHC
GLGVTAMYADAELTNALPNISPLQADGLQSLKGDGFAYGYSVGAQLHPSKSLTIGASYRS
CCCEEEEEECCHHHHCCCCCCCCCCCCHHHHCCCCEEEEEECCCEECCCCCEEEECHHHH
KLDHKLDGTVKVSGLLAPIPAASNFTVDGQAKITLPWIANLGARWAVNDQWTLNGSVSRV
HCCCCCCCEEEEEEEEECCCCCCCEEECCCEEEEEEEHHCCCCEEECCCEEEECCCCEEC
GWSEFDAIRVSFAGGGSTSPQDYKDVTTYAAGVDYQASPRLTLRAGVQYDPTPTPEIGRT
CCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCEECCCCCCCCCCC
ARVPDGDRMMYATGATWAATETLQLDAAISYIAFDKSQINRTDVTATSSTVRLRGDVEGS
CCCCCCCEEEEEECCCEEEEEEEEECCEEEEEEECHHHCCCCEEEECCCEEEEEECCCCC
AVVLAAGARFSF
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]