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The map label for this gene is emrA [C]

Identifier: 16126331

GI number: 16126331

Start: 2300886

End: 2301890

Strand: Direct

Name: emrA [C]

Synonym: CC_2092

Alternate gene names: 16126331

Gene position: 2300886-2301890 (Clockwise)

Preceding gene: 16126330

Following gene: 16126332

Centisome position: 57.28

GC content: 69.25

Gene sequence:

>1005_bases
ATGCCCGGCTTCCTGCGCCGACCCGCCTTCTACATCGCCCTGGTCGTCGTGCTGCTGCTCGGCGGCGGCTTGTTCTACGC
CAAAGGCCAACAGGCCGAGAAAAAGAAGAAGCTTGAGGCCGCCGCCGCTCAAGAAGAGCCCTCCCCCTACGCGGCCATCG
CCCAGGGCAAGGCCGACGTCGAGGGCGGCGTGATCCAGGTGGCCGCGCGCCGCCAGGGCATCATCCGCGAGGTGTTCGTC
CAGGAAGGCGACATCGTCAAAGCCGGCCAGCCCCTGGCCAAGCAAGAGGACGACGACGCCCGCCTGGCGACTCAGACCGC
TTCGGCGGCCCTGGCCTCGGCCAAGGCGCAGCTGGCGCTGCATCAGGTGCAACTGCGCACCGCCCAGCGCGAGTTCAACC
GTCTGCAAGGCTTGGCCGCCTCGAACTATGTAGCCGCTCAGCGGCTGGACGCCGCCCGCGACCAGATCGCCCAGGCTCAG
GCCAACATCGGCACCCAGCAGGCCCAGATCAGCGTCGCTTCGGCCCAGCTGGCCCAGGCCCGCTTCAACGAGGAGCTGAC
GGTGATCCGCGCCCCGGCCGACGGCCGTATCGCCCGCCGCCAGGCCAATCCGGGCTCGGGCGCCTCGACCCTGAACGTCA
CGGCCATGTTCGACCTCGAGCCGAACACCCAGCGCATCGCCCGCGCCGAGATCGTCGAGGCCGACATCCCGAACGTGACC
ATCGGCCAGGAAGTCGAAATCCAGCCTGAAGGCGATCCGGACAAGACCTATGTCGGCAAGGTCCTGCGCCGCGCCGCCGT
CTTCGGCGCCCGCAAGCTGGCCTCGGACGATCCCAGCCAGCGCAGCGACGAGCGCGTCGTCGAAGTGGTGGTCAGCGCCG
ACGGCGCCCCGCTGCTGGTCGGCCAGCGCGTGCTGGTGAAGTTCATGAAGCCCGGCCAGAAGGCCGGCGTGAAGCGGGAT
AAGCCGACCCAGCCGGTGGCCGGCGGGATGACGAAGAAGAGCTAA

Upstream 100 bases:

>100_bases
TCATCCACATCGAAGACGGCCGGATCCTGGACGACGTGCGTAGAACGCCCGACGCCAATCCTGCGCCGCTCAGCCACTGA
TTTTCTGGGGGAATTTCGAC

Downstream 100 bases:

>100_bases
GGGCCCCGCCTTAGCGCACACTGCCTTGGAACGCCGCGCGGCCCCCGCGCGGCGTTTTTCGTTGGCGCTGCCGGGGACAC
CCGGTGTGACGTAGGCCGTG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPGFLRRPAFYIALVVVLLLGGGLFYAKGQQAEKKKKLEAAAAQEEPSPYAAIAQGKADVEGGVIQVAARRQGIIREVFV
QEGDIVKAGQPLAKQEDDDARLATQTASAALASAKAQLALHQVQLRTAQREFNRLQGLAASNYVAAQRLDAARDQIAQAQ
ANIGTQQAQISVASAQLAQARFNEELTVIRAPADGRIARRQANPGSGASTLNVTAMFDLEPNTQRIARAEIVEADIPNVT
IGQEVEIQPEGDPDKTYVGKVLRRAAVFGARKLASDDPSQRSDERVVEVVVSADGAPLLVGQRVLVKFMKPGQKAGVKRD
KPTQPVAGGMTKKS

Sequences:

>Translated_334_residues
MPGFLRRPAFYIALVVVLLLGGGLFYAKGQQAEKKKKLEAAAAQEEPSPYAAIAQGKADVEGGVIQVAARRQGIIREVFV
QEGDIVKAGQPLAKQEDDDARLATQTASAALASAKAQLALHQVQLRTAQREFNRLQGLAASNYVAAQRLDAARDQIAQAQ
ANIGTQQAQISVASAQLAQARFNEELTVIRAPADGRIARRQANPGSGASTLNVTAMFDLEPNTQRIARAEIVEADIPNVT
IGQEVEIQPEGDPDKTYVGKVLRRAAVFGARKLASDDPSQRSDERVVEVVVSADGAPLLVGQRVLVKFMKPGQKAGVKRD
KPTQPVAGGMTKKS
>Mature_333_residues
PGFLRRPAFYIALVVVLLLGGGLFYAKGQQAEKKKKLEAAAAQEEPSPYAAIAQGKADVEGGVIQVAARRQGIIREVFVQ
EGDIVKAGQPLAKQEDDDARLATQTASAALASAKAQLALHQVQLRTAQREFNRLQGLAASNYVAAQRLDAARDQIAQAQA
NIGTQQAQISVASAQLAQARFNEELTVIRAPADGRIARRQANPGSGASTLNVTAMFDLEPNTQRIARAEIVEADIPNVTI
GQEVEIQPEGDPDKTYVGKVLRRAAVFGARKLASDDPSQRSDERVVEVVVSADGAPLLVGQRVLVKFMKPGQKAGVKRDK
PTQPVAGGMTKKS

Specific function: The Emr Locus Confers Resistance To Substances Of High Hydrophobicity. Emra Probably Participate In A Transport System To Extrude Toxins And Drugs From The Cell. [C]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0194 family [H]

Homologues:

Organism=Escherichia coli, GI1789041, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081796, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787013, Length=304, Percent_Identity=26.9736842105263, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082036, Length=179, Percent_Identity=31.2849162011173, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143
- InterPro:   IPR022936 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 35631; Mature: 35500

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGFLRRPAFYIALVVVLLLGGGLFYAKGQQAEKKKKLEAAAAQEEPSPYAAIAQGKADV
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCC
EGGVIQVAARRQGIIREVFVQEGDIVKAGQPLAKQEDDDARLATQTASAALASAKAQLAL
CCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQVQLRTAQREFNRLQGLAASNYVAAQRLDAARDQIAQAQANIGTQQAQISVASAQLAQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RFNEELTVIRAPADGRIARRQANPGSGASTLNVTAMFDLEPNTQRIARAEIVEADIPNVT
HCCCCEEEEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCC
IGQEVEIQPEGDPDKTYVGKVLRRAAVFGARKLASDDPSQRSDERVVEVVVSADGAPLLV
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCCHH
GQRVLVKFMKPGQKAGVKRDKPTQPVAGGMTKKS
HHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PGFLRRPAFYIALVVVLLLGGGLFYAKGQQAEKKKKLEAAAAQEEPSPYAAIAQGKADV
CCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCC
EGGVIQVAARRQGIIREVFVQEGDIVKAGQPLAKQEDDDARLATQTASAALASAKAQLAL
CCCEEEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HQVQLRTAQREFNRLQGLAASNYVAAQRLDAARDQIAQAQANIGTQQAQISVASAQLAQA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RFNEELTVIRAPADGRIARRQANPGSGASTLNVTAMFDLEPNTQRIARAEIVEADIPNVT
HCCCCEEEEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCCC
IGQEVEIQPEGDPDKTYVGKVLRRAAVFGARKLASDDPSQRSDERVVEVVVSADGAPLLV
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEEECCCCCCCHH
GQRVLVKFMKPGQKAGVKRDKPTQPVAGGMTKKS
HHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA