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The map label for this gene is ppiD [H]

Identifier: 16126137

GI number: 16126137

Start: 2089441

End: 2091405

Strand: Direct

Name: ppiD [H]

Synonym: CC_1894

Alternate gene names: 16126137

Gene position: 2089441-2091405 (Clockwise)

Preceding gene: 16126134

Following gene: 16126138

Centisome position: 52.02

GC content: 66.36

Gene sequence:

>1965_bases
ATGCTCGCCGGTTTCCGCAAGTTCGCCAAATCGCCCTTCGCGGTGGTGCTGTTTGGCTTGCTGATTGTCAGCTTCGCCAT
CTTCGGTATTAGCGACGTGTTCAAGGGCCCGCAGGGATCGGGCGTAATCAGCGCCGGCTCGCGCAGTATGAGCGCGATCG
ATTTCAAGCAGCGCTTTGACAACTATCGCAAGGCGATGGAGCAGCAGAACGGCACGACCCTGACTCCCGATCAGGCGGTT
GAGCAGGGCGTCGATCGTCAGATCGTCCAGGAACTGGTGCTGCAAGAATCGCTGGCCGCCGCTCTTCACAAGATGGGGGT
CGCCCCGTCCGACAAGCTGGTGGCCGATACGGTTCACGAGCAGATGAGCCAACTGCCGCCGACGACCCGTCCTTTCGACC
CGATCACCGGCAAGTTCGATTCTCGCGCCTATGCGACGCTGATGCAGCAGAACGGTCTCACCCCGGAGACCTATGAAGCT
TCGCTGCGCGATGAGATCGCCCAGACCCACTTCTTCTCGGCGATCGCCGACGGCCTGAAAGCGCCCCGCATCTATGCGGC
GCTTCAGGGCGCCTACCTGCTGGAGGCGCGTGAGGTCTCGGCCTTCGTCGTCAACCCCTCGACGGTTCAGCGACCGAACC
CGCCGACTGATGCGCAGTTGACGGCGTTCATGAAGGAAAACGCCGATCGGCTGACCCGCCCTGAAACCCGGGTTCTGTCG
ATCATGCGGGTCAGCGCCACTGCGCTGGAGCCATCGGTGACGATCAATCCCGCCGATGTCCAGAAGGCCTTCGACTTCCG
GAAGGATAGCCTGGCCAGGCCCGAGACCCGCACGATCGTTCAGATCGCCGCGCCCGACGCCAAGGCGGCCGCAGTGATCT
CCCAGCGTCTCGGCAAGGGCGAGGACCCCGCAGCCGTCGCCAAGGCCTACGGCAAGACGCCGCTGGTCCTGACCGACAAG
CCCAAGAGCGCCGTTCCCGATCGCAAGGTCGCCGACGCCGCCTTCGCCCTGCAGACCGGCCAGGTCAGCGGCCCGATCAT
CGGCGACCTGGGCGTCGCCGTCGTCAAGGTAACCAAGATCACGCCCGGCGCCGTCGCGACGCTGGACAGCGTCCGCCCGC
AGATCGAGGCCGAGGTCCGGAGCCAGACGGCTCAAGCCAAGGCCTATGAGCAGACCCAGACCTACCAGGATGCTCGTGAC
GCGGGCGCTGATCTCATCTCGGCGGCCAGCAAGGCCGGCGCGCTGGTCATCACGACCGCCCCGGTGACGGCGCAGGGAAC
CGACCAGATGGGCCAGCCCTTCGCCGGCCTGACGCCGGACATTATCAAGACCGCGTTCGATCTGTCGCAAGGTGGCGAGA
GCGAGCTGGTCGAGGCCGGCAAGGGCGAATACTACGCCGTCAAGGTCGAGCGGATCGTGCCTGCGGCCCTGCCGCCGCTG
GCCGAGGTCAAGCCGCAACTGACGGCCGTCTGGTTTGGTCAGGAGATGGCCAAGCGGATGAAGGCCAAGGCCGATGAGCT
GGCCGCACGTGTCAAGAAGGGCGAGAGCCTGGAGGCGGTCGCCACCGCGGCTCAATCGAATGTGCAGAAGATCCCCGGCG
GCCTGACCCGCCAGAACGCTCAACAGCACGTGGCGCTGGGGCAGGAGTTCCTGGGCGCGGCCTTCACGGCCAAGCCGGGC
GCTGTGTTCACCGCGCGCGCCGGTCAGCAGGGCCAGGCCTATGTCGTCGCCAAGCTGGACGCCGTCCGCGCCGCGCCAAC
CGCCAATGTCGCCCAGATCGCTGTTCTGGCCCAAGGTCAGGCCGCCAACGGGCTGATGCGCGACCTGGCCGAGGCCACGC
GCGTCGTCGCCCGCACCCAGATGAAGGCCAAGAGCAACCTGACCCTGGCCCGCCAAGCCATCGGCGTCGACACCGACGCC
CTGGCCAAGGCCGAGGCCGCCAAGGCTGGAAAGAAAGCCGAGTAA

Upstream 100 bases:

>100_bases
CCCACGCCGCTTGCCCCCTCGCCTTCGGCTCTACTATACCCGCTGCTCTCGACCGTCGCGTCCCTGTGCGCAGCGGTCTG
TCTGGAAGGTTTTCGCGCTC

Downstream 100 bases:

>100_bases
TGAGTTTGGAGCCCGCGTTCGACGCCTTCTCGGAAGCCTATGACTCCGGGCGGCAGCAAGTCGTTTGGACCCGCCTGATC
GACGATCTGGAGACGCCGGT

Product: rotamase family protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MLAGFRKFAKSPFAVVLFGLLIVSFAIFGISDVFKGPQGSGVISAGSRSMSAIDFKQRFDNYRKAMEQQNGTTLTPDQAV
EQGVDRQIVQELVLQESLAAALHKMGVAPSDKLVADTVHEQMSQLPPTTRPFDPITGKFDSRAYATLMQQNGLTPETYEA
SLRDEIAQTHFFSAIADGLKAPRIYAALQGAYLLEAREVSAFVVNPSTVQRPNPPTDAQLTAFMKENADRLTRPETRVLS
IMRVSATALEPSVTINPADVQKAFDFRKDSLARPETRTIVQIAAPDAKAAAVISQRLGKGEDPAAVAKAYGKTPLVLTDK
PKSAVPDRKVADAAFALQTGQVSGPIIGDLGVAVVKVTKITPGAVATLDSVRPQIEAEVRSQTAQAKAYEQTQTYQDARD
AGADLISAASKAGALVITTAPVTAQGTDQMGQPFAGLTPDIIKTAFDLSQGGESELVEAGKGEYYAVKVERIVPAALPPL
AEVKPQLTAVWFGQEMAKRMKAKADELAARVKKGESLEAVATAAQSNVQKIPGGLTRQNAQQHVALGQEFLGAAFTAKPG
AVFTARAGQQGQAYVVAKLDAVRAAPTANVAQIAVLAQGQAANGLMRDLAEATRVVARTQMKAKSNLTLARQAIGVDTDA
LAKAEAAKAGKKAE

Sequences:

>Translated_654_residues
MLAGFRKFAKSPFAVVLFGLLIVSFAIFGISDVFKGPQGSGVISAGSRSMSAIDFKQRFDNYRKAMEQQNGTTLTPDQAV
EQGVDRQIVQELVLQESLAAALHKMGVAPSDKLVADTVHEQMSQLPPTTRPFDPITGKFDSRAYATLMQQNGLTPETYEA
SLRDEIAQTHFFSAIADGLKAPRIYAALQGAYLLEAREVSAFVVNPSTVQRPNPPTDAQLTAFMKENADRLTRPETRVLS
IMRVSATALEPSVTINPADVQKAFDFRKDSLARPETRTIVQIAAPDAKAAAVISQRLGKGEDPAAVAKAYGKTPLVLTDK
PKSAVPDRKVADAAFALQTGQVSGPIIGDLGVAVVKVTKITPGAVATLDSVRPQIEAEVRSQTAQAKAYEQTQTYQDARD
AGADLISAASKAGALVITTAPVTAQGTDQMGQPFAGLTPDIIKTAFDLSQGGESELVEAGKGEYYAVKVERIVPAALPPL
AEVKPQLTAVWFGQEMAKRMKAKADELAARVKKGESLEAVATAAQSNVQKIPGGLTRQNAQQHVALGQEFLGAAFTAKPG
AVFTARAGQQGQAYVVAKLDAVRAAPTANVAQIAVLAQGQAANGLMRDLAEATRVVARTQMKAKSNLTLARQAIGVDTDA
LAKAEAAKAGKKAE
>Mature_654_residues
MLAGFRKFAKSPFAVVLFGLLIVSFAIFGISDVFKGPQGSGVISAGSRSMSAIDFKQRFDNYRKAMEQQNGTTLTPDQAV
EQGVDRQIVQELVLQESLAAALHKMGVAPSDKLVADTVHEQMSQLPPTTRPFDPITGKFDSRAYATLMQQNGLTPETYEA
SLRDEIAQTHFFSAIADGLKAPRIYAALQGAYLLEAREVSAFVVNPSTVQRPNPPTDAQLTAFMKENADRLTRPETRVLS
IMRVSATALEPSVTINPADVQKAFDFRKDSLARPETRTIVQIAAPDAKAAAVISQRLGKGEDPAAVAKAYGKTPLVLTDK
PKSAVPDRKVADAAFALQTGQVSGPIIGDLGVAVVKVTKITPGAVATLDSVRPQIEAEVRSQTAQAKAYEQTQTYQDARD
AGADLISAASKAGALVITTAPVTAQGTDQMGQPFAGLTPDIIKTAFDLSQGGESELVEAGKGEYYAVKVERIVPAALPPL
AEVKPQLTAVWFGQEMAKRMKAKADELAARVKKGESLEAVATAAQSNVQKIPGGLTRQNAQQHVALGQEFLGAAFTAKPG
AVFTARAGQQGQAYVVAKLDAVRAAPTANVAQIAVLAQGQAANGLMRDLAEATRVVARTQMKAKSNLTLARQAIGVDTDA
LAKAEAAKAGKKAE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=539, Percent_Identity=23.3766233766234, Blast_Score=130, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69187; Mature: 69187

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGFRKFAKSPFAVVLFGLLIVSFAIFGISDVFKGPQGSGVISAGSRSMSAIDFKQRFD
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
NYRKAMEQQNGTTLTPDQAVEQGVDRQIVQELVLQESLAAALHKMGVAPSDKLVADTVHE
HHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QMSQLPPTTRPFDPITGKFDSRAYATLMQQNGLTPETYEASLRDEIAQTHFFSAIADGLK
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
APRIYAALQGAYLLEAREVSAFVVNPSTVQRPNPPTDAQLTAFMKENADRLTRPETRVLS
CCHHHHHHCCHHEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHH
IMRVSATALEPSVTINPADVQKAFDFRKDSLARPETRTIVQIAAPDAKAAAVISQRLGKG
HHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCC
EDPAAVAKAYGKTPLVLTDKPKSAVPDRKVADAAFALQTGQVSGPIIGDLGVAVVKVTKI
CCHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHEECCCCCCCCHHCCCEEEEEEEEC
TPGAVATLDSVRPQIEAEVRSQTAQAKAYEQTQTYQDARDAGADLISAASKAGALVITTA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PVTAQGTDQMGQPFAGLTPDIIKTAFDLSQGGESELVEAGKGEYYAVKVERIVPAALPPL
CCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEHHHCCCCCCCH
AEVKPQLTAVWFGQEMAKRMKAKADELAARVKKGESLEAVATAAQSNVQKIPGGLTRQNA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
QQHVALGQEFLGAAFTAKPGAVFTARAGQQGQAYVVAKLDAVRAAPTANVAQIAVLAQGQ
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEHHHHHCCCCCCHHEEEEEECCC
AANGLMRDLAEATRVVARTQMKAKSNLTLARQAIGVDTDALAKAEAAKAGKKAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLAGFRKFAKSPFAVVLFGLLIVSFAIFGISDVFKGPQGSGVISAGSRSMSAIDFKQRFD
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
NYRKAMEQQNGTTLTPDQAVEQGVDRQIVQELVLQESLAAALHKMGVAPSDKLVADTVHE
HHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
QMSQLPPTTRPFDPITGKFDSRAYATLMQQNGLTPETYEASLRDEIAQTHFFSAIADGLK
HHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
APRIYAALQGAYLLEAREVSAFVVNPSTVQRPNPPTDAQLTAFMKENADRLTRPETRVLS
CCHHHHHHCCHHEEEEECCEEEEECCCCCCCCCCCCCHHHHHHHHHCHHHHCCCHHHHHH
IMRVSATALEPSVTINPADVQKAFDFRKDSLARPETRTIVQIAAPDAKAAAVISQRLGKG
HHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCC
EDPAAVAKAYGKTPLVLTDKPKSAVPDRKVADAAFALQTGQVSGPIIGDLGVAVVKVTKI
CCHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHEECCCCCCCCHHCCCEEEEEEEEC
TPGAVATLDSVRPQIEAEVRSQTAQAKAYEQTQTYQDARDAGADLISAASKAGALVITTA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
PVTAQGTDQMGQPFAGLTPDIIKTAFDLSQGGESELVEAGKGEYYAVKVERIVPAALPPL
CCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEHHHCCCCCCCH
AEVKPQLTAVWFGQEMAKRMKAKADELAARVKKGESLEAVATAAQSNVQKIPGGLTRQNA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHH
QQHVALGQEFLGAAFTAKPGAVFTARAGQQGQAYVVAKLDAVRAAPTANVAQIAVLAQGQ
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEHHHHHCCCCCCHHEEEEEECCC
AANGLMRDLAEATRVVARTQMKAKSNLTLARQAIGVDTDALAKAEAAKAGKKAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]