Click here to switch to the map view.

The map label for this gene is ntrY [H]

Identifier: 16125986

GI number: 16125986

Start: 1915429

End: 1917579

Strand: Direct

Name: ntrY [H]

Synonym: CC_1742

Alternate gene names: 16125986

Gene position: 1915429-1917579 (Clockwise)

Preceding gene: 16125985

Following gene: 16125987

Centisome position: 47.68

GC content: 66.06

Gene sequence:

>2151_bases
ATGGGCGGCGGATACGCGCTGGCGGTGATCTTGACCGTCACAGGCGTCGCCCTGGCGTCTTCACCACCGCGCACGGACTC
GATCGGCGCCGCCAGCACCGTCATCCTGGTGGTGCTCGGCTTCAATCTCGTGCTCATTCTGGGCGTCGCGACCATCGTCG
GCCTGCGTCTGTATGAGCTGATCGACGCACGGGCCAGCGACGCAGGCGCTCGCCTGCACCTGCGCTTTGTAGGCCTGTTT
TCGCTGGCGGCCGTGGCGCCTGCCGTCATCGTCGCCCTGTTCTTCGGCGTGCTGGTCAACCGCGGCGTCGATGGCTGGTT
CAGTGAGCGGGTCCAGACCGTGGTCGGCAACTCGGCCAAGGTCGCCAATTCCTACGTCGAACAGCAGAAGAACTATATTT
CCGAGCATATCGGCCCGATGGCGGCCAGCCTGAACCAGGCCGCTCCGGCGCTGGCGCAGTCCCCAGTCGCTTTCGGTCAC
TTTCTGGCCGGCCTGACGCAGGACAACGGATTTTCGGCCGCCTATGTGCTCGATCGCGACGGTCGGATTCTGGCCCGCAC
CGAGGCGGAAGGCGCGCCGCCCTTCCTGGCGCCGCCGCCCGCAAGTTTCGATTGGGCGGATGGCGGCGAGGCGAGCGCTC
AGCGCTTTGTATCGACGGACCTGTTCCGCACGCTCTACAAGCTCAAGGGGTTCGACGACGGCTATCTCTACGTCGTTCGA
CCGATCGAGAAGGGCATTCTCAACCACCTCATCGAAACTCAGGACGCCCTGGTCTCCTATCGCGACGCCGAGCGCAGTCG
CGGCCGCATCCAGGCGATCTTCGGGTTGAGCTATCTGGAGACGGCCCTGCTTGTGCTGGTGGCCGCCATTTGGGTGGGCA
TCGCGGCGGCGAACTCCATCGCCGGGCCCGTCGCAGGCCTCGTCGAGGCGGCCGGCCGCGTCTCAGGCGGCGATCTCGAC
GCACGTGTGGAAGTCGAGCGGGGGCCAGAGGAAATCCGAGCGCTGTCCAACGCTTTCAACATGATGACCAGCGAGCTCCA
GCTCCAGCAGGCCGCGCTGAAGGCCGCCAGCCTGGACGCCGAAAGCCGCCGTCAGTTCATCGAGACAGTGCTTTCGGGCG
TCAGCGCGGGCGTGGTCAGCCTCGATGATCGCGGCAAGATCTCGGCGGTCAACCGGCGCGCTGTGGCGCTCTTGGGCTTG
CCCGATGACGCGCTCGGCGTGGATCTCATCGCGCTGGCGCCAGAGTTCGAAACGGTCATGACCTCGCTCTCGGAAAGCCG
GCCCGATACGGACGTCGAGGTCGACATCATGCGCGAGGGCGAGACGCGTCGGCTCCGCGTGCGGGCGGCCGGCCATTTCG
CAGAAGGGCTCGTTCTGACCTTCGATGATATCACCCGTCTGGTGGCGGCCCAGCGAAATGCAGCCTGGAAGGACGTCGCC
CGGCGGATCGCCCATGAGATCAAGAACCCGCTGACGCCGATCCAGCTGTCTGCGGAACGTCTTCGCCGGAAGTACCGCAA
GGAGATCGCAAGCGACCTGGAGACTTTCGATCGCTGCACCGACACCATCATCCGGCAGGTTGGCGACATCGGGCGCATGG
TCGACGAGTTCTCAGCGTTCGCTCGCATGCCCGCGCCGCGCTTCGAGCCGTCGAACCTCACGGAAATGCTGCGGCAGGCT
GTCTTCGCCCAACGGTTCCAGGACGCCGAGATTGAGGTCAGACTGGAGGAGCCAGGCGATGGCGACGTCTGGATCACCAG
CGATGAACGAATGGTCGGCCAGGCGCTGACCAACATCCTGAAGAACGCCGGCGAGGCGGTCGGCGCGCGCCGCGCCAACG
AGCCTGAGCTCCAAGGGCGCATCACCGCGACCCTCGTCTGTGAAGGCGACGAGCTGTGCGTGACGGTCGAGGACAACGGT
GTGGGTCTGCCCGCCAAGGACCGCGACCGCCTGACCGAACCCTATGTGACCACCCGCGAGAAGGGCACAGGCCTTGGCCT
GGCCATCGTCAAGCGGATCATGGAGGACCACGGCGGCAGCCTGGCCCTCGTCGATGCGCGCGAGCCGCCTGGCGCGCGCG
TCGTGATGAAGTTTCCAACGACCGCGCGTCTGCCCGTCGCGGCCCAGAGTGGCGTTGAGGAGATGATATGA

Upstream 100 bases:

>100_bases
GTGAGCGATGTCTTCAGTGGCTTACGCGACGGGATCCGATAGCCCGCCGACCCGGTTTAGCCGGGCCTGGTGGCGGGGGG
TGTTGCGGTCGCGCTATCTG

Downstream 100 bases:

>100_bases
GCGCCGACGTTCTTGTGGTGGATGACGAGGCCGACATTCGGGATCTCGTCGCCGGCATCCTGGAGGATGAAGGCTATGCT
GTGCGCACGGCCGCCGACTC

Product: nitrogen regulation protein NtrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MGGGYALAVILTVTGVALASSPPRTDSIGAASTVILVVLGFNLVLILGVATIVGLRLYELIDARASDAGARLHLRFVGLF
SLAAVAPAVIVALFFGVLVNRGVDGWFSERVQTVVGNSAKVANSYVEQQKNYISEHIGPMAASLNQAAPALAQSPVAFGH
FLAGLTQDNGFSAAYVLDRDGRILARTEAEGAPPFLAPPPASFDWADGGEASAQRFVSTDLFRTLYKLKGFDDGYLYVVR
PIEKGILNHLIETQDALVSYRDAERSRGRIQAIFGLSYLETALLVLVAAIWVGIAAANSIAGPVAGLVEAAGRVSGGDLD
ARVEVERGPEEIRALSNAFNMMTSELQLQQAALKAASLDAESRRQFIETVLSGVSAGVVSLDDRGKISAVNRRAVALLGL
PDDALGVDLIALAPEFETVMTSLSESRPDTDVEVDIMREGETRRLRVRAAGHFAEGLVLTFDDITRLVAAQRNAAWKDVA
RRIAHEIKNPLTPIQLSAERLRRKYRKEIASDLETFDRCTDTIIRQVGDIGRMVDEFSAFARMPAPRFEPSNLTEMLRQA
VFAQRFQDAEIEVRLEEPGDGDVWITSDERMVGQALTNILKNAGEAVGARRANEPELQGRITATLVCEGDELCVTVEDNG
VGLPAKDRDRLTEPYVTTREKGTGLGLAIVKRIMEDHGGSLALVDAREPPGARVVMKFPTTARLPVAAQSGVEEMI

Sequences:

>Translated_716_residues
MGGGYALAVILTVTGVALASSPPRTDSIGAASTVILVVLGFNLVLILGVATIVGLRLYELIDARASDAGARLHLRFVGLF
SLAAVAPAVIVALFFGVLVNRGVDGWFSERVQTVVGNSAKVANSYVEQQKNYISEHIGPMAASLNQAAPALAQSPVAFGH
FLAGLTQDNGFSAAYVLDRDGRILARTEAEGAPPFLAPPPASFDWADGGEASAQRFVSTDLFRTLYKLKGFDDGYLYVVR
PIEKGILNHLIETQDALVSYRDAERSRGRIQAIFGLSYLETALLVLVAAIWVGIAAANSIAGPVAGLVEAAGRVSGGDLD
ARVEVERGPEEIRALSNAFNMMTSELQLQQAALKAASLDAESRRQFIETVLSGVSAGVVSLDDRGKISAVNRRAVALLGL
PDDALGVDLIALAPEFETVMTSLSESRPDTDVEVDIMREGETRRLRVRAAGHFAEGLVLTFDDITRLVAAQRNAAWKDVA
RRIAHEIKNPLTPIQLSAERLRRKYRKEIASDLETFDRCTDTIIRQVGDIGRMVDEFSAFARMPAPRFEPSNLTEMLRQA
VFAQRFQDAEIEVRLEEPGDGDVWITSDERMVGQALTNILKNAGEAVGARRANEPELQGRITATLVCEGDELCVTVEDNG
VGLPAKDRDRLTEPYVTTREKGTGLGLAIVKRIMEDHGGSLALVDAREPPGARVVMKFPTTARLPVAAQSGVEEMI
>Mature_715_residues
GGGYALAVILTVTGVALASSPPRTDSIGAASTVILVVLGFNLVLILGVATIVGLRLYELIDARASDAGARLHLRFVGLFS
LAAVAPAVIVALFFGVLVNRGVDGWFSERVQTVVGNSAKVANSYVEQQKNYISEHIGPMAASLNQAAPALAQSPVAFGHF
LAGLTQDNGFSAAYVLDRDGRILARTEAEGAPPFLAPPPASFDWADGGEASAQRFVSTDLFRTLYKLKGFDDGYLYVVRP
IEKGILNHLIETQDALVSYRDAERSRGRIQAIFGLSYLETALLVLVAAIWVGIAAANSIAGPVAGLVEAAGRVSGGDLDA
RVEVERGPEEIRALSNAFNMMTSELQLQQAALKAASLDAESRRQFIETVLSGVSAGVVSLDDRGKISAVNRRAVALLGLP
DDALGVDLIALAPEFETVMTSLSESRPDTDVEVDIMREGETRRLRVRAAGHFAEGLVLTFDDITRLVAAQRNAAWKDVAR
RIAHEIKNPLTPIQLSAERLRRKYRKEIASDLETFDRCTDTIIRQVGDIGRMVDEFSAFARMPAPRFEPSNLTEMLRQAV
FAQRFQDAEIEVRLEEPGDGDVWITSDERMVGQALTNILKNAGEAVGARRANEPELQGRITATLVCEGDELCVTVEDNGV
GLPAKDRDRLTEPYVTTREKGTGLGLAIVKRIMEDHGGSLALVDAREPPGARVVMKFPTTARLPVAAQSGVEEMI

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=342, Percent_Identity=23.9766081871345, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1790300, Length=335, Percent_Identity=28.3582089552239, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.0542986425339, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=30.8641975308642, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=255, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77068; Mature: 76937

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGGYALAVILTVTGVALASSPPRTDSIGAASTVILVVLGFNLVLILGVATIVGLRLYEL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDARASDAGARLHLRFVGLFSLAAVAPAVIVALFFGVLVNRGVDGWFSERVQTVVGNSAK
HHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
VANSYVEQQKNYISEHIGPMAASLNQAAPALAQSPVAFGHFLAGLTQDNGFSAAYVLDRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECC
GRILARTEAEGAPPFLAPPPASFDWADGGEASAQRFVSTDLFRTLYKLKGFDDGYLYVVR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
PIEKGILNHLIETQDALVSYRDAERSRGRIQAIFGLSYLETALLVLVAAIWVGIAAANSI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGPVAGLVEAAGRVSGGDLDARVEVERGPEEIRALSNAFNMMTSELQLQQAALKAASLDA
HHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ESRRQFIETVLSGVSAGVVSLDDRGKISAVNRRAVALLGLPDDALGVDLIALAPEFETVM
HHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCHHCCCCEEECCHHHHHH
TSLSESRPDTDVEVDIMREGETRRLRVRAAGHFAEGLVLTFDDITRLVAAQRNAAWKDVA
HHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHCCCHHHHHH
RRIAHEIKNPLTPIQLSAERLRRKYRKEIASDLETFDRCTDTIIRQVGDIGRMVDEFSAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARMPAPRFEPSNLTEMLRQAVFAQRFQDAEIEVRLEEPGDGDVWITSDERMVGQALTNIL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHH
KNAGEAVGARRANEPELQGRITATLVCEGDELCVTVEDNGVGLPAKDRDRLTEPYVTTRE
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCC
KGTGLGLAIVKRIMEDHGGSLALVDAREPPGARVVMKFPTTARLPVAAQSGVEEMI
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHCCHHHCC
>Mature Secondary Structure 
GGGYALAVILTVTGVALASSPPRTDSIGAASTVILVVLGFNLVLILGVATIVGLRLYEL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDARASDAGARLHLRFVGLFSLAAVAPAVIVALFFGVLVNRGVDGWFSERVQTVVGNSAK
HHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
VANSYVEQQKNYISEHIGPMAASLNQAAPALAQSPVAFGHFLAGLTQDNGFSAAYVLDRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECC
GRILARTEAEGAPPFLAPPPASFDWADGGEASAQRFVSTDLFRTLYKLKGFDDGYLYVVR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
PIEKGILNHLIETQDALVSYRDAERSRGRIQAIFGLSYLETALLVLVAAIWVGIAAANSI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGPVAGLVEAAGRVSGGDLDARVEVERGPEEIRALSNAFNMMTSELQLQQAALKAASLDA
HHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ESRRQFIETVLSGVSAGVVSLDDRGKISAVNRRAVALLGLPDDALGVDLIALAPEFETVM
HHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCHHCCCCEEECCHHHHHH
TSLSESRPDTDVEVDIMREGETRRLRVRAAGHFAEGLVLTFDDITRLVAAQRNAAWKDVA
HHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEHHHHHHHHHHHCCCHHHHHH
RRIAHEIKNPLTPIQLSAERLRRKYRKEIASDLETFDRCTDTIIRQVGDIGRMVDEFSAF
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARMPAPRFEPSNLTEMLRQAVFAQRFQDAEIEVRLEEPGDGDVWITSDERMVGQALTNIL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHH
KNAGEAVGARRANEPELQGRITATLVCEGDELCVTVEDNGVGLPAKDRDRLTEPYVTTRE
HHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCHHHCCCCCCCCCC
KGTGLGLAIVKRIMEDHGGSLALVDAREPPGARVVMKFPTTARLPVAAQSGVEEMI
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]