Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 16125861

GI number: 16125861

Start: 1786961

End: 1788136

Strand: Direct

Name: aroB [H]

Synonym: CC_1614

Alternate gene names: 16125861

Gene position: 1786961-1788136 (Clockwise)

Preceding gene: 16125858

Following gene: 16125862

Centisome position: 44.49

GC content: 68.45

Gene sequence:

>1176_bases
ATGCTATGGTCGACTCGAAATGAGGCGTCGCAACTGTTCGCGGCGCCTGCGAGACAGGTGGTTAGGACCATGTCGGAGGC
GCCGCGCGCGCCCGGCGCGCCGAGTGGGCGGCGCCGGCGGTCGCCGGAAGAGACGTCGTGCTATGCGGCGCTTGATCTGG
GGACCAACAATTGCCGCCTTTTGGTGGCCACGCCGAGCCCGCGCGGATTCCGCGTGGTCGAGGCCTATTCCCGCATCGTG
CGTCTGGGCGAGGGGCTGTCGCAGAGCGGCCAGCTGTCGGACGCCGCCATGGAGCGCTCGCTGGCGGCGCTGAAGGTCTG
CGCCGAGAAGATCCGTCGCCGCAAGGCGATCCGCGTCAAGGCGGTGGCGACCCAGGCCTGTCGCGGCGCGACCAACGGCC
CTGACTTCGTGCGACGGGTGCACGAGGAAACGGGGCTGAAGCTGCAGATCATCAGCCCGCGCGAGGAGGCTCAGCTATCC
GTCGCTGGGTGTATGAGCCTGTTTGATCGCCAGCAGGACGCGGCGTTGGTCGTCGATGTCGGCGGCGGCTCGACGGAGCT
GTCCTGGGTGGACCTGAAGGGCGGCGGCCTCGACGCCAAGCCTCGTCAGTTCGCGGCCTGGAAGCTGCCGATCAAGGCCT
GGCTGTCGATCCCCGTCGGTGTTGTGACCCTGGCCGAGCGCTTTCCGGAGGGCGAGCAGGCCAATCCCGTCTGGTTCCGA
GCCATGGTCGATGACGTGAAGGCCCGGATCGAGACCTTCCCGCACGCTGAGCCGATGCGGAAGGTCTTCGCGGAGGGCAG
GGCGCATCTGGTCGGGACGTCCGGCGCCATCACCAGCCTCGCGGGCCTGCATCTGGGCCTGGCGCGCTATGACCGTAACG
TGGTCGACGGACTCTGGATGAACCGGACGGACTGTGACGCGGCGGCGGATCGCTTGCTGGCCCTTACCTCGCCGGAACGC
GCGGCTGAGCCCTGCATCGGAGCCGATCGTGCGGATCTCGTATTGGCCGGCGCGGCGATCCTCCAGGCCGTGCAGGAGCT
CTGGCCATGTTCGCGCGTGCGTGTGGCCGATCGAGGGCTTAGAGAGGGGCTGTTGTTGTCCCTGATGTCCGATCAGCAGC
GACGCCCTCGGCGGCGTCGTCGCGGCGGCGCCTCCAAGAAGTCTGAAGCCGCATGA

Upstream 100 bases:

>100_bases
GAATTCATGGCGCTCAGAATAACAGCCGCACCTGACTGATTCCTGAACGTAAATGCCGGGACACGGATATCAAGGCGGCG
CCTTCCGACGGGCGAGTCAC

Downstream 100 bases:

>100_bases
GTGACGAAGAGCCGCCCCGCAAGCGCATGGTCAAGCCGCCGGCCGGCGGCAATGAAGGCGGACGCGGCAAGCCCGCGCGC
CTGAAGACCGCCTATGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MLWSTRNEASQLFAAPARQVVRTMSEAPRAPGAPSGRRRRSPEETSCYAALDLGTNNCRLLVATPSPRGFRVVEAYSRIV
RLGEGLSQSGQLSDAAMERSLAALKVCAEKIRRRKAIRVKAVATQACRGATNGPDFVRRVHEETGLKLQIISPREEAQLS
VAGCMSLFDRQQDAALVVDVGGGSTELSWVDLKGGGLDAKPRQFAAWKLPIKAWLSIPVGVVTLAERFPEGEQANPVWFR
AMVDDVKARIETFPHAEPMRKVFAEGRAHLVGTSGAITSLAGLHLGLARYDRNVVDGLWMNRTDCDAAADRLLALTSPER
AAEPCIGADRADLVLAGAAILQAVQELWPCSRVRVADRGLREGLLLSLMSDQQRRPRRRRRGGASKKSEAA

Sequences:

>Translated_391_residues
MLWSTRNEASQLFAAPARQVVRTMSEAPRAPGAPSGRRRRSPEETSCYAALDLGTNNCRLLVATPSPRGFRVVEAYSRIV
RLGEGLSQSGQLSDAAMERSLAALKVCAEKIRRRKAIRVKAVATQACRGATNGPDFVRRVHEETGLKLQIISPREEAQLS
VAGCMSLFDRQQDAALVVDVGGGSTELSWVDLKGGGLDAKPRQFAAWKLPIKAWLSIPVGVVTLAERFPEGEQANPVWFR
AMVDDVKARIETFPHAEPMRKVFAEGRAHLVGTSGAITSLAGLHLGLARYDRNVVDGLWMNRTDCDAAADRLLALTSPER
AAEPCIGADRADLVLAGAAILQAVQELWPCSRVRVADRGLREGLLLSLMSDQQRRPRRRRRGGASKKSEAA
>Mature_391_residues
MLWSTRNEASQLFAAPARQVVRTMSEAPRAPGAPSGRRRRSPEETSCYAALDLGTNNCRLLVATPSPRGFRVVEAYSRIV
RLGEGLSQSGQLSDAAMERSLAALKVCAEKIRRRKAIRVKAVATQACRGATNGPDFVRRVHEETGLKLQIISPREEAQLS
VAGCMSLFDRQQDAALVVDVGGGSTELSWVDLKGGGLDAKPRQFAAWKLPIKAWLSIPVGVVTLAERFPEGEQANPVWFR
AMVDDVKARIETFPHAEPMRKVFAEGRAHLVGTSGAITSLAGLHLGLARYDRNVVDGLWMNRTDCDAAADRLLALTSPER
AAEPCIGADRADLVLAGAAILQAVQELWPCSRVRVADRGLREGLLLSLMSDQQRRPRRRRRGGASKKSEAA

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=343, Percent_Identity=29.1545189504373, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788848, Length=328, Percent_Identity=25.609756097561, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321185, Length=347, Percent_Identity=25.6484149855908, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 42562; Mature: 42562

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSTRNEASQLFAAPARQVVRTMSEAPRAPGAPSGRRRRSPEETSCYAALDLGTNNCRL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEE
LVATPSPRGFRVVEAYSRIVRLGEGLSQSGQLSDAAMERSLAALKVCAEKIRRRKAIRVK
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVATQACRGATNGPDFVRRVHEETGLKLQIISPREEAQLSVAGCMSLFDRQQDAALVVDV
HHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEE
GGGSTELSWVDLKGGGLDAKPRQFAAWKLPIKAWLSIPVGVVTLAERFPEGEQANPVWFR
CCCCCEEEEEEECCCCCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHH
AMVDDVKARIETFPHAEPMRKVFAEGRAHLVGTSGAITSLAGLHLGLARYDRNVVDGLWM
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCC
NRTDCDAAADRLLALTSPERAAEPCIGADRADLVLAGAAILQAVQELWPCSRVRVADRGL
CCCCHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
REGLLLSLMSDQQRRPRRRRRGGASKKSEAA
HHHHHHHHHHHHHHCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLWSTRNEASQLFAAPARQVVRTMSEAPRAPGAPSGRRRRSPEETSCYAALDLGTNNCRL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEE
LVATPSPRGFRVVEAYSRIVRLGEGLSQSGQLSDAAMERSLAALKVCAEKIRRRKAIRVK
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVATQACRGATNGPDFVRRVHEETGLKLQIISPREEAQLSVAGCMSLFDRQQDAALVVDV
HHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEE
GGGSTELSWVDLKGGGLDAKPRQFAAWKLPIKAWLSIPVGVVTLAERFPEGEQANPVWFR
CCCCCEEEEEEECCCCCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHH
AMVDDVKARIETFPHAEPMRKVFAEGRAHLVGTSGAITSLAGLHLGLARYDRNVVDGLWM
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHCC
NRTDCDAAADRLLALTSPERAAEPCIGADRADLVLAGAAILQAVQELWPCSRVRVADRGL
CCCCHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
REGLLLSLMSDQQRRPRRRRRGGASKKSEAA
HHHHHHHHHHHHHHCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]