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The map label for this gene is yafC [C]

Identifier: 16125722

GI number: 16125722

Start: 1624306

End: 1625202

Strand: Direct

Name: yafC [C]

Synonym: CC_1474

Alternate gene names: 16125722

Gene position: 1624306-1625202 (Clockwise)

Preceding gene: 16125720

Following gene: 16125725

Centisome position: 40.44

GC content: 71.46

Gene sequence:

>897_bases
ATGTCCAAGCTCCCCGATCTGGAAGGCCTCGCCGTGTTCGCCAAGGTGGCCGAGCTGCGCTCGTTTGCGGCCGCCTCCGA
AGCCTTGGCCCTCTCGAAGGCCACCGTGTCGAAGGCGGTGACGCGGCTTGAGCTGCGCCTTGGGGCTAGGCTCCTCAATC
GCACCTCGCGACGCCTGGCCCTGACCGACGCCGGCCAGGCGCTCGTCGAGCGCGCCAGCCGGGTGCTGGCCGAGGCCGAG
GCCGCCGAGGAGGAGGCCTCCAGCCAGTCTGCAGCGCCACGCGGGCTTGTTCGCATGGCTGCGCCGATGTCGCTGGGCGT
CGCCAGTTTGGCTCCGGTGTTGCCGGCCTTTCTGGAAGCCTATCCGGACGTCTCCATCGACCTGCACCTGTCGGACGCCA
CCGTCGACCTGATCGGTATGGGGTTCGACATCGCCCTGCGCGTCGCGGACTTGCCCGACAGTTCGCTGTTGGCGCGGCGG
CTGCGGGCGGTGCAGCGCCACGTCGTGGCCGCACCGGCCTATTGGACGGCGCACGGGCGTCCGACGCACCCGGCGGACCT
CGCCGAGCATCGCGGATTGACCTATGGCCACCAGGCCTCGCCGGAAACCTGGCGCTTTCAGCGGGCGGGGGGCGAGGAGG
CGGCGGTGCGGCCGCGCTCGGTGCTGCGGGCCAACAATGGTGATGCGCTGTTGCCGCCGCTGCTGGCGGGCACCGGCGTG
GCCATGTTGCCCGACTTCATCGTGGGCCCGGCCCTGGCCGACAGGCGTCTTGAGGCGGTGCTGACCGAATGGAGCGCCGC
GCCGATCGCGTTACACCTTGTCATGCCGCCCGGTGGCCCGCGCCCGGCGCGCGTTTCGGTGCTGGCGGACTACCTGGCCA
AGACGCTCGGGCGCTGA

Upstream 100 bases:

>100_bases
CGCCGCGTCGGCGCGTCCTGTTGAGAAGAAGATAGGCGCGGCGGCGTGATTATAAATCGAAACTATTGAAATCCATCGTT
TCGAAAAATAGCATCTAGCG

Downstream 100 bases:

>100_bases
CGTTCGTCAGCCCAGGCTCTCGACTTGAGCCGGCGTGAAGGCCCCGACCTGAAGCGGCGTCATGGCCGCGATGTTGGTGG
TCGACAGCCAGTCCAGTTGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSKLPDLEGLAVFAKVAELRSFAAASEALALSKATVSKAVTRLELRLGARLLNRTSRRLALTDAGQALVERASRVLAEAE
AAEEEASSQSAAPRGLVRMAAPMSLGVASLAPVLPAFLEAYPDVSIDLHLSDATVDLIGMGFDIALRVADLPDSSLLARR
LRAVQRHVVAAPAYWTAHGRPTHPADLAEHRGLTYGHQASPETWRFQRAGGEEAAVRPRSVLRANNGDALLPPLLAGTGV
AMLPDFIVGPALADRRLEAVLTEWSAAPIALHLVMPPGGPRPARVSVLADYLAKTLGR

Sequences:

>Translated_298_residues
MSKLPDLEGLAVFAKVAELRSFAAASEALALSKATVSKAVTRLELRLGARLLNRTSRRLALTDAGQALVERASRVLAEAE
AAEEEASSQSAAPRGLVRMAAPMSLGVASLAPVLPAFLEAYPDVSIDLHLSDATVDLIGMGFDIALRVADLPDSSLLARR
LRAVQRHVVAAPAYWTAHGRPTHPADLAEHRGLTYGHQASPETWRFQRAGGEEAAVRPRSVLRANNGDALLPPLLAGTGV
AMLPDFIVGPALADRRLEAVLTEWSAAPIALHLVMPPGGPRPARVSVLADYLAKTLGR
>Mature_297_residues
SKLPDLEGLAVFAKVAELRSFAAASEALALSKATVSKAVTRLELRLGARLLNRTSRRLALTDAGQALVERASRVLAEAEA
AEEEASSQSAAPRGLVRMAAPMSLGVASLAPVLPAFLEAYPDVSIDLHLSDATVDLIGMGFDIALRVADLPDSSLLARRL
RAVQRHVVAAPAYWTAHGRPTHPADLAEHRGLTYGHQASPETWRFQRAGGEEAAVRPRSVLRANNGDALLPPLLAGTGVA
MLPDFIVGPALADRRLEAVLTEWSAAPIALHLVMPPGGPRPARVSVLADYLAKTLGR

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=246, Percent_Identity=37.3983739837398, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.312925170068, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=29.757785467128, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=30.952380952381, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87081978, Length=265, Percent_Identity=32.4528301886792, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789440, Length=301, Percent_Identity=26.578073089701, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=28.8808664259928, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=25.0847457627119, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=36.5853658536585, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790399, Length=306, Percent_Identity=26.1437908496732, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=239, Percent_Identity=26.7782426778243, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788706, Length=193, Percent_Identity=26.9430051813472, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31547; Mature: 31416

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLPDLEGLAVFAKVAELRSFAAASEALALSKATVSKAVTRLELRLGARLLNRTSRRLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LTDAGQALVERASRVLAEAEAAEEEASSQSAAPRGLVRMAAPMSLGVASLAPVLPAFLEA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
YPDVSIDLHLSDATVDLIGMGFDIALRVADLPDSSLLARRLRAVQRHVVAAPAYWTAHGR
CCCCEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCC
PTHPADLAEHRGLTYGHQASPETWRFQRAGGEEAAVRPRSVLRANNGDALLPPLLAGTGV
CCCCHHHHHHCCCCCCCCCCCCCEEHHHCCCCCHHCCCHHHHCCCCCCEECCHHHHCCCH
AMLPDFIVGPALADRRLEAVLTEWSAAPIALHLVMPPGGPRPARVSVLADYLAKTLGR
HHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKLPDLEGLAVFAKVAELRSFAAASEALALSKATVSKAVTRLELRLGARLLNRTSRRLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
LTDAGQALVERASRVLAEAEAAEEEASSQSAAPRGLVRMAAPMSLGVASLAPVLPAFLEA
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
YPDVSIDLHLSDATVDLIGMGFDIALRVADLPDSSLLARRLRAVQRHVVAAPAYWTAHGR
CCCCEEEEEECCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCC
PTHPADLAEHRGLTYGHQASPETWRFQRAGGEEAAVRPRSVLRANNGDALLPPLLAGTGV
CCCCHHHHHHCCCCCCCCCCCCCEEHHHCCCCCHHCCCHHHHCCCCCCEECCHHHHCCCH
AMLPDFIVGPALADRRLEAVLTEWSAAPIALHLVMPPGGPRPARVSVLADYLAKTLGR
HHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]