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The map label for this gene is ihfA

Identifier: 16125619

GI number: 16125619

Start: 1522587

End: 1522889

Strand: Direct

Name: ihfA

Synonym: CC_1370

Alternate gene names: 16125619

Gene position: 1522587-1522889 (Clockwise)

Preceding gene: 16125618

Following gene: 16125620

Centisome position: 37.9

GC content: 67.66

Gene sequence:

>303_bases
ATGAAGGGCGCTACTTTGACCCGGGCCGACCTGTGCGAGGCGGTTCATGAGGAAGTCGGACTGACCCGCCAGGACTGCGC
GGGACTGGTCGAGCGCACTCTTGATCTCGTCGCCGAGGCGCTGGAGCAGGGCGAAACTGTCAAGCTGTCCGGGTTCGGCG
TCTTCCAGGTCCGCGCCAAGCGCGCGCGCATGGGGCGCAATCCCAAGACCGGCGAGCCCGCTGAGATCGAGCCGCGGCGC
GTGATCGGCTTCCGCGCTTCGCAGGTCATGAAGGCGCGCATCGATCGCGCTCTGGGCGGCTAA

Upstream 100 bases:

>100_bases
CGCGGCCAGTTGAGGGCGGCCGCAACATGCCAGGGTTCGCCGCGAGTGCTCCAGCTAGGGCGACCTCCAAGGTCGCTCCG
ATACGCGTGAAGGGGGTTGC

Downstream 100 bases:

>100_bases
GGATCGATTGCGGTGGCGAAGGGGCCAAACGCCTTCCGCACGATCTCCGAAGCCGCCGAGGAGCTTGGCGTGCCGCAGCA
CGTGCTTCGCTTCTGGGAAA

Product: integration host factor alpha-subunit

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAKRARMGRNPKTGEPAEIEPRR
VIGFRASQVMKARIDRALGG

Sequences:

>Translated_100_residues
MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAKRARMGRNPKTGEPAEIEPRR
VIGFRASQVMKARIDRALGG
>Mature_100_residues
MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAKRARMGRNPKTGEPAEIEPRR
VIGFRASQVMKARIDRALGG

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=47.8260869565217, Blast_Score=90, Evalue=3e-20,
Organism=Escherichia coli, GI1790433, Length=86, Percent_Identity=31.3953488372093, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_CAUCN (B8H546)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002516806.1
- ProteinModelPortal:   B8H546
- SMR:   B8H546
- GeneID:   7330162
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01433
- OMA:   VRGETVK
- ProtClustDB:   PRK00285
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 10893; Mature: 10893

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAK
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RARMGRNPKTGEPAEIEPRRVIGFRASQVMKARIDRALGG
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGATLTRADLCEAVHEEVGLTRQDCAGLVERTLDLVAEALEQGETVKLSGFGVFQVRAK
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
RARMGRNPKTGEPAEIEPRRVIGFRASQVMKARIDRALGG
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA