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The map label for this gene is guaAA [H]

Identifier: 16124664

GI number: 16124664

Start: 427638

End: 428354

Strand: Direct

Name: guaAA [H]

Synonym: CC_0409

Alternate gene names: 16124664

Gene position: 427638-428354 (Clockwise)

Preceding gene: 16124663

Following gene: 16124668

Centisome position: 10.65

GC content: 70.01

Gene sequence:

>717_bases
GTGGCGACGCGCGTCTTGAAGATCGGCCTGCTGGAAACGGGCGAGCCGCCGGGCCCGCTGAAGGCGACCTATGGCGGCTA
TGGATCGATGTTCGAGACCCTGCTGGGCGATGGCCACGCCTACCGCGCCTACGACGTCCAACGCGGCGAGCTGCCGGCGC
ATCCGGCCGAGAACGACGCCTATGTGATCACCGGCTCCTCGGCGGGGGTCTATGATCCGCTGCCCTGGATCGAGCCGCTG
AAGGCCTTCCTGCGGTCGGCCCGGGGCGAGACCCCCTTGGTCGGGGTCTGTTTTGGCCATCAGATCATGGCCGAGGCGTT
CGGCGGCAAGGTCGAGAAGTCGCCCAAGGGCTGGGGCGTGGGCCTGCAGGCCTATGCGGTCGCCGAGCGCGCCGTCTGGA
TGGATGACGCCGCGGAGGTCGCCGTGCCGGGCTCGCACCAGGACCAGGTCGTGGACCTGCCGCCCACGGCGCGGGTTCTG
GCCGGCAGCGCGTTCACGCCCTACGGCATCCTCGCCTATGACGACGCGCCGGCGATCTCGATGCAGTTCCACCCGGAGTT
CGCGCCCGACTACGCCAAGGCCCTGATCGAGGCGCGGCGCGGGACGCGTTACACCGATCCGCAGGCCGATGCGGCGATCG
CCAGCCTGGATAGTCCCAACGACCGGGCGCGGATGGCCGACTGGATCCGGCGGTTCCTCGCGCAGGCTTCAAGCTGA

Upstream 100 bases:

>100_bases
AGATCGAGCTCTGGTGGATCGACCAGGACTTCATCGAGGACAAGTTCAGCGCCATCGAGCGCCTGAAGGCCGTCGCCCAG
GGCATGGTCTACTGATCGCC

Downstream 100 bases:

>100_bases
GGCGCTGGGGGCGTCCTCGCCCTTCGACAAGCTCAGGGTGAGGACGACTGCTGGTCTCGGCGCGTACAAAATCCTCATCC
TGAGCTTGTCGAAGGACGAG

Product: glutamine amidotransferase, class-I family protein

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MATRVLKIGLLETGEPPGPLKATYGGYGSMFETLLGDGHAYRAYDVQRGELPAHPAENDAYVITGSSAGVYDPLPWIEPL
KAFLRSARGETPLVGVCFGHQIMAEAFGGKVEKSPKGWGVGLQAYAVAERAVWMDDAAEVAVPGSHQDQVVDLPPTARVL
AGSAFTPYGILAYDDAPAISMQFHPEFAPDYAKALIEARRGTRYTDPQADAAIASLDSPNDRARMADWIRRFLAQASS

Sequences:

>Translated_238_residues
MATRVLKIGLLETGEPPGPLKATYGGYGSMFETLLGDGHAYRAYDVQRGELPAHPAENDAYVITGSSAGVYDPLPWIEPL
KAFLRSARGETPLVGVCFGHQIMAEAFGGKVEKSPKGWGVGLQAYAVAERAVWMDDAAEVAVPGSHQDQVVDLPPTARVL
AGSAFTPYGILAYDDAPAISMQFHPEFAPDYAKALIEARRGTRYTDPQADAAIASLDSPNDRARMADWIRRFLAQASS
>Mature_237_residues
ATRVLKIGLLETGEPPGPLKATYGGYGSMFETLLGDGHAYRAYDVQRGELPAHPAENDAYVITGSSAGVYDPLPWIEPLK
AFLRSARGETPLVGVCFGHQIMAEAFGGKVEKSPKGWGVGLQAYAVAERAVWMDDAAEVAVPGSHQDQVVDLPPTARVLA
GSAFTPYGILAYDDAPAISMQFHPEFAPDYAKALIEARRGTRYTDPQADAAIASLDSPNDRARMADWIRRFLAQASS

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323155, Length=169, Percent_Identity=30.1775147928994, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR004739 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25554; Mature: 25423

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRVLKIGLLETGEPPGPLKATYGGYGSMFETLLGDGHAYRAYDVQRGELPAHPAENDA
CCCEEEEEEEEECCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCE
YVITGSSAGVYDPLPWIEPLKAFLRSARGETPLVGVCFGHQIMAEAFGGKVEKSPKGWGV
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCC
GLQAYAVAERAVWMDDAAEVAVPGSHQDQVVDLPPTARVLAGSAFTPYGILAYDDAPAIS
CHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECCCCHHHHCCCCCCCCEEEEECCCCEEE
MQFHPEFAPDYAKALIEARRGTRYTDPQADAAIASLDSPNDRARMADWIRRFLAQASS
EEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATRVLKIGLLETGEPPGPLKATYGGYGSMFETLLGDGHAYRAYDVQRGELPAHPAENDA
CCEEEEEEEEECCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCE
YVITGSSAGVYDPLPWIEPLKAFLRSARGETPLVGVCFGHQIMAEAFGGKVEKSPKGWGV
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCC
GLQAYAVAERAVWMDDAAEVAVPGSHQDQVVDLPPTARVLAGSAFTPYGILAYDDAPAIS
CHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECCCCHHHHCCCCCCCCEEEEECCCCEEE
MQFHPEFAPDYAKALIEARRGTRYTDPQADAAIASLDSPNDRARMADWIRRFLAQASS
EEECCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]