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The map label for this gene is ucpA [C]

Identifier: 16124653

GI number: 16124653

Start: 419728

End: 420699

Strand: Direct

Name: ucpA [C]

Synonym: CC_0398

Alternate gene names: 16124653

Gene position: 419728-420699 (Clockwise)

Preceding gene: 16124652

Following gene: 16124654

Centisome position: 10.45

GC content: 67.7

Gene sequence:

>972_bases
ATGAGCGGACGGATCACATCGGCCTTTGGGGCCAAGTCGACGGCGCGTGAGGTTGTCGCCGGGCATGACCTTTCCGGTCG
CGTGGCGATCGTCACCGGGGCGGCCACCGGCATCGGGGTGGAGACCGCTCGCGCCCTGGCCCTGGCCGGCGCCGAAGTGA
TCATCGCCGCCCGCAAGCCGGAGCTGGGCGAAGAGGTCGCCAACGCCATCAATGAAGAGGCCGGGTCCAAGCGGGTCAGC
TTCGGCATGCTGGATCTCTCCAGCCTTGAGGCCATCCGTCACTTCGTGAACGTCTGGGGCGATCGCCGCATCGACATCCT
GATCAACAACGCCGCCGTCATGGCCAGTCCGCTGATGCGCACCGCCGACGGCTTCGAGATGCAGTTCGGCACCAATCACC
TGGGCCATTTCCTGCTGTCGGTGCTGCTGGCCCCGAACCTGATCGCCGGCGCCAAGGCCAGCGGCAAGCCTTCGCGACTG
GTCTCGCTGTCGTCGATCGGCCACCGGCGCTCGGGGATCCATTTCGACGATCCCAACTACACCACCCGCCCCTACGAGAA
GTGGGAGGCCTATGGTCAGGCCAAGACCGCCAACAGCCTGTTCGCGGTGGGTTTCGACAAGCGCTTCAAGGATCAGGGCG
TCCACGCCAACGCCGTCATGCCGGGCGGCATCCTGACCCCGCTGCAACGCCACCTGCCGATCGAGGAGCAGCGCGCTCTG
GGCTGGCTGGATGAGAACGACCAGCCGCGCGAGGGCTTCAAGACGACCGAACAAGGCGCGGCGACCAGCGTCTGGGCGGC
GGTGGGAAGCGAGCTGGAGGGCGTCGGCGGGCTCTATCTGGAGGACTGCAACCAGGCGCTGCCCTGGAGCAAGGAAAACC
CCTGGACCGGCGTGATGCCGCACGCCCTGGACCCCGAGGCCGCCGATCGGCTCTGGGACCTGTCGGTCGACATCGTCGGG
GCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGGCGCGCCTACGGTCCGCTGTGCCTTGCGATCGCTCTGGGGATTTGCGCGATCCAGATGTAGCCTAGCCAGCATAACA
ACAAGCGGGAGGAAGCGGGC

Downstream 100 bases:

>100_bases
TGGAGCGGGCCACCACGCTGCGCCTCGCGGGCGTGGCGGTGCTGCTGGGCGTGGCGATAGACGTCGTCGCGCCCTTCCTG
ATCTACCCGCGCCTGGTCGA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKPELGEEVANAINEEAGSKRVS
FGMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMRTADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRL
VSLSSIGHRRSGIHFDDPNYTTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRAL
GWLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMPHALDPEAADRLWDLSVDIVG
AGA

Sequences:

>Translated_323_residues
MSGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKPELGEEVANAINEEAGSKRVS
FGMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMRTADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRL
VSLSSIGHRRSGIHFDDPNYTTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRAL
GWLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMPHALDPEAADRLWDLSVDIVG
AGA
>Mature_322_residues
SGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKPELGEEVANAINEEAGSKRVSF
GMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMRTADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRLV
SLSSIGHRRSGIHFDDPNYTTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRALG
WLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMPHALDPEAADRLWDLSVDIVGA
GA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=306, Percent_Identity=41.5032679738562, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI166795268, Length=300, Percent_Identity=40, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI7706523, Length=320, Percent_Identity=34.6875, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI186928839, Length=300, Percent_Identity=39, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI10190746, Length=312, Percent_Identity=36.2179487179487, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI193804850, Length=296, Percent_Identity=39.527027027027, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI19923931, Length=272, Percent_Identity=40.4411764705882, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI146231950, Length=309, Percent_Identity=35.5987055016181, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI7705421, Length=236, Percent_Identity=26.6949152542373, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193207620, Length=331, Percent_Identity=32.3262839879154, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17532805, Length=331, Percent_Identity=30.2114803625378, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17558006, Length=312, Percent_Identity=30.4487179487179, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17532791, Length=332, Percent_Identity=29.5180722891566, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71992402, Length=294, Percent_Identity=31.6326530612245, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI72001364, Length=302, Percent_Identity=29.8013245033113, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535059, Length=288, Percent_Identity=30.9027777777778, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32565532, Length=236, Percent_Identity=31.3559322033898, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17505416, Length=285, Percent_Identity=29.4736842105263, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324820, Length=238, Percent_Identity=28.9915966386555, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573296, Length=301, Percent_Identity=37.5415282392027, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI22024069, Length=293, Percent_Identity=38.2252559726962, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24586328, Length=300, Percent_Identity=37.6666666666667, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI19921754, Length=297, Percent_Identity=37.037037037037, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI45554248, Length=294, Percent_Identity=38.4353741496599, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24640117, Length=294, Percent_Identity=38.4353741496599, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20129347, Length=330, Percent_Identity=33.9393939393939, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI161076371, Length=270, Percent_Identity=40, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24647946, Length=317, Percent_Identity=31.8611987381703, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24656154, Length=319, Percent_Identity=31.6614420062696, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19922628, Length=319, Percent_Identity=31.6614420062696, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI45553409, Length=302, Percent_Identity=32.4503311258278, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24647948, Length=302, Percent_Identity=32.4503311258278, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24647931, Length=309, Percent_Identity=28.4789644012945, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34504; Mature: 34373

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKP
CCCCCCCHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCC
ELGEEVANAINEEAGSKRVSFGMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMR
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
TADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRLVSLSSIGHRRSGIHFDDPNY
CCCCCEEECCCHHHHHHHHHHHHCCCHHCCCCCCCCCHHEEEHHHCCCCCCCCCCCCCCC
TTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRAL
CCCCHHHHHHHCCCCCCCCEEEECCCHHHHHCCCEECEECCCHHHHHHHHCCCCHHHHHC
GWLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCHHHHHCCCCCCCCCCCCCCCCCC
HALDPEAADRLWDLSVDIVGAGA
CCCCHHHHHHHEECEEEEEECCC
>Mature Secondary Structure 
SGRITSAFGAKSTAREVVAGHDLSGRVAIVTGAATGIGVETARALALAGAEVIIAARKP
CCCCCCHHCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCC
ELGEEVANAINEEAGSKRVSFGMLDLSSLEAIRHFVNVWGDRRIDILINNAAVMASPLMR
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHH
TADGFEMQFGTNHLGHFLLSVLLAPNLIAGAKASGKPSRLVSLSSIGHRRSGIHFDDPNY
CCCCCEEECCCHHHHHHHHHHHHCCCHHCCCCCCCCCHHEEEHHHCCCCCCCCCCCCCCC
TTRPYEKWEAYGQAKTANSLFAVGFDKRFKDQGVHANAVMPGGILTPLQRHLPIEEQRAL
CCCCHHHHHHHCCCCCCCCEEEECCCHHHHHCCCEECEECCCHHHHHHHHCCCCHHHHHC
GWLDENDQPREGFKTTEQGAATSVWAAVGSELEGVGGLYLEDCNQALPWSKENPWTGVMP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCHHHHHCCCCCCCCCCCCCCCCCC
HALDPEAADRLWDLSVDIVGAGA
CCCCHHHHHHHEECEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]