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The map label for this gene is paaG [H]

Identifier: 16124652

GI number: 16124652

Start: 418501

End: 419271

Strand: Direct

Name: paaG [H]

Synonym: CC_0397

Alternate gene names: 16124652

Gene position: 418501-419271 (Clockwise)

Preceding gene: 16124651

Following gene: 16124653

Centisome position: 10.42

GC content: 72.11

Gene sequence:

>771_bases
ATGACCGACCATGTGACGGTGCAGATCGACGCCGGCGTGATGACCCTCACCCTGGCGCGCCCGGAAAAGAAGAACGCGCT
CTCCAACGCGATGTACGGCGTGCTCGCCGACAGCCTGGAGGCGGCCGAAAAGGATCCGACCATCCGTGTGGTAGTCTTCC
AGGGCGATGGCGACAGCTTCACCGCCGGCAACGACCTGCAGGACTTCGCCGCCCAGGCCACCGGCGCCTTCAGCGGCGAG
CGGCACGTGACCCGATTCCTGAAGGCCCTGGCGAACGCCACCCGACCGCTGGTCGCGGCCGTGCAGGGCCAGGCGGTCGG
GGTGGGGACCACCATGCTGCTGCACTGCGACCTGGTGTTCGTCAGCCCCGACGCGCGCCTGACCACGCCGTTCGTCAACC
TGGCCCTGGTGCCGGAGGCGGCGTCCAGCTGGCTGCTGCCGGCGCGGGTGGGCCACGCCCGCGCCTACGCCATGTTCGCC
CTCGGCGAGGCGGTGGACGGCGCCACGGCGGTGGCCTGGGGCCTGGCCAACGCGCTTGTGGAGCAGGGCGATCTGCGCGC
CCGGGCGCGCGCCGCCGCCGACCAGCTGGCCAAGCGTCCGCTGGGCGCGCTGACCGTGACCAAGCGGCTGATGCGCGACG
CCGAGAAGATCGCCCAGCTGATGGACACCGAGGGCGCGGAGTTCGCCGCGCGTCTGCAGACCGCCGAGGCGCGCGAAGCC
TTCATGGCCTTCGCCGAACGCCGCGCGCCCGACTTCAGCAAGGCCGGCTAG

Upstream 100 bases:

>100_bases
TCAACGCCCAGCTCACCGAAGGCTTCACGGACGAGGAAATCAGCGTGGTCTCGCGCTGGCTCGCCAGTCTGCAGACCAAG
TTCCCCAAGGGAGACCCGCA

Downstream 100 bases:

>100_bases
GCCGTGCTGCTGACCCTGCTGCTGACCGGGGTCTTTTTCCTGCTCGCGGGCGTCCATCTCTACTGGGCGTTCGGCGGGCG
GTGGCCCGGCCATGACGAGG

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTDHVTVQIDAGVMTLTLARPEKKNALSNAMYGVLADSLEAAEKDPTIRVVVFQGDGDSFTAGNDLQDFAAQATGAFSGE
RHVTRFLKALANATRPLVAAVQGQAVGVGTTMLLHCDLVFVSPDARLTTPFVNLALVPEAASSWLLPARVGHARAYAMFA
LGEAVDGATAVAWGLANALVEQGDLRARARAAADQLAKRPLGALTVTKRLMRDAEKIAQLMDTEGAEFAARLQTAEAREA
FMAFAERRAPDFSKAG

Sequences:

>Translated_256_residues
MTDHVTVQIDAGVMTLTLARPEKKNALSNAMYGVLADSLEAAEKDPTIRVVVFQGDGDSFTAGNDLQDFAAQATGAFSGE
RHVTRFLKALANATRPLVAAVQGQAVGVGTTMLLHCDLVFVSPDARLTTPFVNLALVPEAASSWLLPARVGHARAYAMFA
LGEAVDGATAVAWGLANALVEQGDLRARARAAADQLAKRPLGALTVTKRLMRDAEKIAQLMDTEGAEFAARLQTAEAREA
FMAFAERRAPDFSKAG
>Mature_255_residues
TDHVTVQIDAGVMTLTLARPEKKNALSNAMYGVLADSLEAAEKDPTIRVVVFQGDGDSFTAGNDLQDFAAQATGAFSGER
HVTRFLKALANATRPLVAAVQGQAVGVGTTMLLHCDLVFVSPDARLTTPFVNLALVPEAASSWLLPARVGHARAYAMFAL
GEAVDGATAVAWGLANALVEQGDLRARARAAADQLAKRPLGALTVTKRLMRDAEKIAQLMDTEGAEFAARLQTAEAREAF
MAFAERRAPDFSKAG

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=252, Percent_Identity=28.968253968254, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI260275230, Length=252, Percent_Identity=28.968253968254, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI260274832, Length=252, Percent_Identity=28.968253968254, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=25.3012048192771, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31542718, Length=257, Percent_Identity=26.4591439688716, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4757968, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI49355787, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI25453481, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI51538573, Length=256, Percent_Identity=24.21875, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4757966, Length=214, Percent_Identity=25.7009345794392, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI51538581, Length=214, Percent_Identity=25.7009345794392, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4502327, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI70995211, Length=152, Percent_Identity=26.9736842105263, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=33.587786259542, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1787659, Length=242, Percent_Identity=31.404958677686, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=26.9372693726937, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788597, Length=248, Percent_Identity=25, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=29.5719844357977, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25145438, Length=246, Percent_Identity=29.6747967479675, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=217, Percent_Identity=31.7972350230415, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=25.8964143426295, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17540714, Length=200, Percent_Identity=28, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=245, Percent_Identity=24.0816326530612, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=27.2, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=26.3374485596708, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=26.3374485596708, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=29.0196078431373, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=25.5605381165919, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27097; Mature: 26966

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHVTVQIDAGVMTLTLARPEKKNALSNAMYGVLADSLEAAEKDPTIRVVVFQGDGDSF
CCCCEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TAGNDLQDFAAQATGAFSGERHVTRFLKALANATRPLVAAVQGQAVGVGTTMLLHCDLVF
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEECCCCEEEEEEEEEE
VSPDARLTTPFVNLALVPEAASSWLLPARVGHARAYAMFALGEAVDGATAVAWGLANALV
ECCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EQGDLRARARAAADQLAKRPLGALTVTKRLMRDAEKIAQLMDTEGAEFAARLQTAEAREA
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FMAFAERRAPDFSKAG
HHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDHVTVQIDAGVMTLTLARPEKKNALSNAMYGVLADSLEAAEKDPTIRVVVFQGDGDSF
CCCEEEEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
TAGNDLQDFAAQATGAFSGERHVTRFLKALANATRPLVAAVQGQAVGVGTTMLLHCDLVF
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEECCCCEEEEEEEEEE
VSPDARLTTPFVNLALVPEAASSWLLPARVGHARAYAMFALGEAVDGATAVAWGLANALV
ECCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EQGDLRARARAAADQLAKRPLGALTVTKRLMRDAEKIAQLMDTEGAEFAARLQTAEAREA
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FMAFAERRAPDFSKAG
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]