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The map label for this gene is asd [H]

Identifier: 16124508

GI number: 16124508

Start: 265999

End: 267027

Strand: Direct

Name: asd [H]

Synonym: CC_0253

Alternate gene names: 16124508

Gene position: 265999-267027 (Clockwise)

Preceding gene: 16124506

Following gene: 16124509

Centisome position: 6.62

GC content: 63.95

Gene sequence:

>1029_bases
ATGGGTTACCGGGTCGCCGTGGTCGGCGCCACGGGCAATGTGGGCCGCGAGATGTTCAACATCCTCGAGGAAGTCAAATT
CCCCGTGGACAAGATGCACGCCATCGCCAGCCGCAAATCCATCGGCGTCGAGGTCTCGTTCGGCAACGAGATCCTCAAGT
GTGAGGACCTGGAGCAGTTCGACTTCTCCAAGGTCGATCTCGTGCTGATGAGCGCCGGCGGTTCGATCTCCAAGGCCTGG
GGCGAGAAGATCGGCGCGGCCGGTCCGATCGTCATCGACAACTCCAGCCACTTCCGGATGGACCCGGACGTGCCGCTGGT
GGTGCCGGAGGTGAACCCGGAAGCCGTCAACAGCATCCCCAAGAACATCATCGCCAATCCGAACTGCTCGACGGCCCAGC
TGGTGGTGGCGCTGAAGCCGCTGCACGATGAGGCCAAGATCAAGCGGGTGGTCGTCTCGACCTACCAGTCTGTCTCCGGC
GCGGGCAAGGAGGGCATGGACGAGCTCTGGGACCAGACCAAGGGCGTCTATGTCCTGGGCGCGCCGCCGCCCAAGAAGTT
CACCAAACAGATCGCCTTCAACGTCATCCCCCACATCGACGTCTTCATGGACGACGGCTTCACCAAGGAAGAGTGGAAGA
TGGCCGTCGAGACCCAGAAGATCCTGGATCCGGCGATCAAGCTGACCGCCACCTGCGTGCGCGTGCCGGTCATGGTCGGC
CACTCGGAGTCGGTGAACGTCGAGTTCGAGAGCCCGCTGGACGAGGATGAGGCCCGCGAGATCCTGCGCGAGGCCGACGG
CATCGTCGTGGTCGATAAGCGCGAGGACGGCGGCTACATCACGCCCAAGGAATCCCAGGGCGAGTTCCCGGTCTACATCT
CGCGCATCCGCAAGGACCCGACCGTCGAGAACGGCCTGGCGTTCTGGTGCGTGTCGGACAACCTGCGCAAGGGCGCGGCG
CTGAACGCGGTGCAGATCGCCCAGCTGCTGCACGACAAGGGCCTGCTGAAGCGCAAGGTCCTGGCCTAG

Upstream 100 bases:

>100_bases
CGCGCCTGAGAGAAACCCTCGGCTTGCGCCCGCTGGGCATGAGGCGTAACGGAACCACGCCCCGCGAGGTCCGCCGGGCG
ACAGTCTTCAGGAGAGCGCG

Downstream 100 bases:

>100_bases
GACGGTCCCCGCCGTCCTTCGCCCAGCGGAGGACGGCGGATTTCCTGGTCGCAAACCCAGAATTTCCCAACTCTCCGCAA
GATGCGGGCGGATGGCGGGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MGYRVAVVGATGNVGREMFNILEEVKFPVDKMHAIASRKSIGVEVSFGNEILKCEDLEQFDFSKVDLVLMSAGGSISKAW
GEKIGAAGPIVIDNSSHFRMDPDVPLVVPEVNPEAVNSIPKNIIANPNCSTAQLVVALKPLHDEAKIKRVVVSTYQSVSG
AGKEGMDELWDQTKGVYVLGAPPPKKFTKQIAFNVIPHIDVFMDDGFTKEEWKMAVETQKILDPAIKLTATCVRVPVMVG
HSESVNVEFESPLDEDEAREILREADGIVVVDKREDGGYITPKESQGEFPVYISRIRKDPTVENGLAFWCVSDNLRKGAA
LNAVQIAQLLHDKGLLKRKVLA

Sequences:

>Translated_342_residues
MGYRVAVVGATGNVGREMFNILEEVKFPVDKMHAIASRKSIGVEVSFGNEILKCEDLEQFDFSKVDLVLMSAGGSISKAW
GEKIGAAGPIVIDNSSHFRMDPDVPLVVPEVNPEAVNSIPKNIIANPNCSTAQLVVALKPLHDEAKIKRVVVSTYQSVSG
AGKEGMDELWDQTKGVYVLGAPPPKKFTKQIAFNVIPHIDVFMDDGFTKEEWKMAVETQKILDPAIKLTATCVRVPVMVG
HSESVNVEFESPLDEDEAREILREADGIVVVDKREDGGYITPKESQGEFPVYISRIRKDPTVENGLAFWCVSDNLRKGAA
LNAVQIAQLLHDKGLLKRKVLA
>Mature_341_residues
GYRVAVVGATGNVGREMFNILEEVKFPVDKMHAIASRKSIGVEVSFGNEILKCEDLEQFDFSKVDLVLMSAGGSISKAWG
EKIGAAGPIVIDNSSHFRMDPDVPLVVPEVNPEAVNSIPKNIIANPNCSTAQLVVALKPLHDEAKIKRVVVSTYQSVSGA
GKEGMDELWDQTKGVYVLGAPPPKKFTKQIAFNVIPHIDVFMDDGFTKEEWKMAVETQKILDPAIKLTATCVRVPVMVGH
SESVNVEFESPLDEDEAREILREADGIVVVDKREDGGYITPKESQGEFPVYISRIRKDPTVENGLAFWCVSDNLRKGAAL
NAVQIAQLLHDKGLLKRKVLA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=333, Percent_Identity=35.7357357357357, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1789841, Length=353, Percent_Identity=25.2124645892351, Blast_Score=88, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=397, Percent_Identity=27.2040302267003, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37483; Mature: 37351

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRVAVVGATGNVGREMFNILEEVKFPVDKMHAIASRKSIGVEVSFGNEILKCEDLEQF
CCEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEECCCCEEEECCCCCC
DFSKVDLVLMSAGGSISKAWGEKIGAAGPIVIDNSSHFRMDPDVPLVVPEVNPEAVNSIP
CCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCEEEECCCHHHHHHCC
KNIIANPNCSTAQLVVALKPLHDEAKIKRVVVSTYQSVSGAGKEGMDELWDQTKGVYVLG
HHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEE
APPPKKFTKQIAFNVIPHIDVFMDDGFTKEEWKMAVETQKILDPAIKLTATCVRVPVMVG
CCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
HSESVNVEFESPLDEDEAREILREADGIVVVDKREDGGYITPKESQGEFPVYISRIRKDP
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCCHHHHHHCCCC
TVENGLAFWCVSDNLRKGAALNAVQIAQLLHDKGLLKRKVLA
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
GYRVAVVGATGNVGREMFNILEEVKFPVDKMHAIASRKSIGVEVSFGNEILKCEDLEQF
CEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCEEEEECCCCEEEECCCCCC
DFSKVDLVLMSAGGSISKAWGEKIGAAGPIVIDNSSHFRMDPDVPLVVPEVNPEAVNSIP
CCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCEEEECCCHHHHHHCC
KNIIANPNCSTAQLVVALKPLHDEAKIKRVVVSTYQSVSGAGKEGMDELWDQTKGVYVLG
HHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEE
APPPKKFTKQIAFNVIPHIDVFMDDGFTKEEWKMAVETQKILDPAIKLTATCVRVPVMVG
CCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
HSESVNVEFESPLDEDEAREILREADGIVVVDKREDGGYITPKESQGEFPVYISRIRKDP
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCCEECCCCCCCCCCHHHHHHCCCC
TVENGLAFWCVSDNLRKGAALNAVQIAQLLHDKGLLKRKVLA
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]