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The map label for this gene is tadA [H]

Identifier: 16124486

GI number: 16124486

Start: 247055

End: 247540

Strand: Direct

Name: tadA [H]

Synonym: CC_0231

Alternate gene names: 16124486

Gene position: 247055-247540 (Clockwise)

Preceding gene: 16124484

Following gene: 16124488

Centisome position: 6.15

GC content: 70.37

Gene sequence:

>486_bases
ATGCGCACTGATGAGAGCGAGGATCAAGACCACCGCATGATGCGCCTGGCGCTCGACGCCGCGCGCGCCGCAGCCGAGGC
GGGCGAAACGCCGGTCGGGGCGGTGATCCTGGATCCCAGCACCGGCGAGGTGATCGCGACCGCCGGCAACGGCCCGATCG
CGGCCCATGACCCCACCGCCCACGCCGAGATCGCCGCCATGCGCGCTGCGGCCGCCAAGCTTGGCAACTATCGCCTGACG
GACCTGACCTTGGTGGTGACCTTGGAGCCTTGCGCCATGTGCGCCGGGGCGATCAGCCACGCGCGGATCGGGCGGGTGGT
GTTCGGGGCTGACGACCCGAAGGGCGGCGCCGTTGTGCATGGTCCGAAATTCTTCGCCCAGCCGACCTGCCATTGGCGGC
CTGAGGTGACGGGCGGCGTGCTGGCCGACGAGAGCGCGGATCTGTTGCGCGGCTTCTTTCGCGCGCGCCGCAAGGCCAAG
ATCTAG

Upstream 100 bases:

>100_bases
CTTGACCGTCGAGGTGAGGCTCGTACAGGGGATCGTGGGGTTTGGTCATGGCGCGTCCTTCTTGGGCTGGGCGCATCTCT
CGATGGGCTTTCGGTTTCTA

Downstream 100 bases:

>100_bases
TTGACCATCGCGGAGGTCAGCAGAACCTTCGAGCCCGGCTTGCCCAGCACCTGGTCGGCGGTCTTCTGCAACTCGCGGCC
CACGTGATCGATGTCCGGCG

Product: cytidine and deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRTDESEDQDHRMMRLALDAARAAAEAGETPVGAVILDPSTGEVIATAGNGPIAAHDPTAHAEIAAMRAAAAKLGNYRLT
DLTLVVTLEPCAMCAGAISHARIGRVVFGADDPKGGAVVHGPKFFAQPTCHWRPEVTGGVLADESADLLRGFFRARRKAK
I

Sequences:

>Translated_161_residues
MRTDESEDQDHRMMRLALDAARAAAEAGETPVGAVILDPSTGEVIATAGNGPIAAHDPTAHAEIAAMRAAAAKLGNYRLT
DLTLVVTLEPCAMCAGAISHARIGRVVFGADDPKGGAVVHGPKFFAQPTCHWRPEVTGGVLADESADLLRGFFRARRKAK
I
>Mature_161_residues
MRTDESEDQDHRMMRLALDAARAAAEAGETPVGAVILDPSTGEVIATAGNGPIAAHDPTAHAEIAAMRAAAAKLGNYRLT
DLTLVVTLEPCAMCAGAISHARIGRVVFGADDPKGGAVVHGPKFFAQPTCHWRPEVTGGVLADESADLLRGFFRARRKAK
I

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=154, Percent_Identity=51.2987012987013, Blast_Score=141, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=36, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322425, Length=158, Percent_Identity=34.1772151898734, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355527, Length=149, Percent_Identity=34.2281879194631, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16895; Mature: 16895

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDESEDQDHRMMRLALDAARAAAEAGETPVGAVILDPSTGEVIATAGNGPIAAHDPTA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCEECCCCCC
HAEIAAMRAAAAKLGNYRLTDLTLVVTLEPCAMCAGAISHARIGRVVFGADDPKGGAVVH
HHHHHHHHHHHHHHCCEEEEEEEEEEEECHHHHHHHHHHHHHHCEEEECCCCCCCCEEEE
GPKFFAQPTCHWRPEVTGGVLADESADLLRGFFRARRKAKI
CCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTDESEDQDHRMMRLALDAARAAAEAGETPVGAVILDPSTGEVIATAGNGPIAAHDPTA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCEECCCCCC
HAEIAAMRAAAAKLGNYRLTDLTLVVTLEPCAMCAGAISHARIGRVVFGADDPKGGAVVH
HHHHHHHHHHHHHHCCEEEEEEEEEEEECHHHHHHHHHHHHHHCEEEECCCCCCCCEEEE
GPKFFAQPTCHWRPEVTGGVLADESADLLRGFFRARRKAKI
CCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]