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The map label for this gene is lpsI [H]

Identifier: 16124461

GI number: 16124461

Start: 220931

End: 221641

Strand: Direct

Name: lpsI [H]

Synonym: CC_0206

Alternate gene names: 16124461

Gene position: 220931-221641 (Clockwise)

Preceding gene: 16124458

Following gene: 16124462

Centisome position: 5.5

GC content: 63.15

Gene sequence:

>711_bases
ATGGTCGACAAGGTGAAGAAGGACGCCGTCGAAGCCCTTGCCGGGCTTTTGTTCGACGGCATGACCATCATGGCCGGCGG
GTTCGGCCTCTGCGGCATTCCGGAGAACCTGATCGCGGCGATCCGCGAGGCGGGAACCAAGGACCTCACGGTCATCTCCA
ACAACTGCGGCGTCGACGGCTTTGGCCTCGGAATCCTGCTCGAGAACCGCCAGATCAAGAAGATGGTCTCGTCCTATGTG
GGCGAGAACAAGCTGTTCGAACAGCTCTATCTCTCGGGCGAACTGGAGCTGGAGTTCAATCCGCAGGGCACCCTGGCCGA
GCGTATCCGCGCCGGCGGCGCGGGCATCCCGGCCTTCTTCACGCGCACCGGCTACGGCACCCTGGTGGCCGAGGGCAAGG
AGACCCGCGAGTTCGACGGCGAGATGTATGTGATGGAGCGCGGCCTGACCGCCGACCTCTCGATCGTCAAGGCCTGGAAG
GCCGACGCCGAGGGCAACCTGATCTATCGAAAGACCGCTCGGAACTTCAATCCGATGATGGCCACGGCGGGCAAGAAGAC
CGTTGTCGAGGTCGAGGAGCTGGTCGCGATCGGCGAGCTTGACAAGGACGCCATCCACACCCCCGGCATCTATGTCGACC
GCCTGATCAAGGGCGCGAAGTTCGAGAAGCGCATCGAGCGCGTGACCACTCGCCAGAAGGAAACCGCGTAA

Upstream 100 bases:

>100_bases
CCTTCGGGAAAATAATTCATCAAGGGTTGAATTTATTCGCGGCTCGGGCGACACGCTGCGCCCAGCGCCAGACGTATAAG
TCTGGGAACAGGGAGACACC

Downstream 100 bases:

>100_bases
TGGCCTGGACCCGCGACGAGGTGGCGGCCCGCGCCGCCAAGGAGCTGCAGGACGGCTTCTACGTGAACCTGGGCATCGGC
ATCCCGACCCTGGTGGCCAA

Product: 3-oxoadipate CoA-transferase subunit alpha

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MVDKVKKDAVEALAGLLFDGMTIMAGGFGLCGIPENLIAAIREAGTKDLTVISNNCGVDGFGLGILLENRQIKKMVSSYV
GENKLFEQLYLSGELELEFNPQGTLAERIRAGGAGIPAFFTRTGYGTLVAEGKETREFDGEMYVMERGLTADLSIVKAWK
ADAEGNLIYRKTARNFNPMMATAGKKTVVEVEELVAIGELDKDAIHTPGIYVDRLIKGAKFEKRIERVTTRQKETA

Sequences:

>Translated_236_residues
MVDKVKKDAVEALAGLLFDGMTIMAGGFGLCGIPENLIAAIREAGTKDLTVISNNCGVDGFGLGILLENRQIKKMVSSYV
GENKLFEQLYLSGELELEFNPQGTLAERIRAGGAGIPAFFTRTGYGTLVAEGKETREFDGEMYVMERGLTADLSIVKAWK
ADAEGNLIYRKTARNFNPMMATAGKKTVVEVEELVAIGELDKDAIHTPGIYVDRLIKGAKFEKRIERVTTRQKETA
>Mature_236_residues
MVDKVKKDAVEALAGLLFDGMTIMAGGFGLCGIPENLIAAIREAGTKDLTVISNNCGVDGFGLGILLENRQIKKMVSSYV
GENKLFEQLYLSGELELEFNPQGTLAERIRAGGAGIPAFFTRTGYGTLVAEGKETREFDGEMYVMERGLTADLSIVKAWK
ADAEGNLIYRKTARNFNPMMATAGKKTVVEVEELVAIGELDKDAIHTPGIYVDRLIKGAKFEKRIERVTTRQKETA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=248, Percent_Identity=58.0645161290323, Blast_Score=288, Evalue=3e-78,
Organism=Homo sapiens, GI11545841, Length=249, Percent_Identity=55.0200803212851, Blast_Score=261, Evalue=4e-70,
Organism=Escherichia coli, GI1788551, Length=213, Percent_Identity=44.6009389671362, Blast_Score=191, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=247, Percent_Identity=53.0364372469636, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21358325, Length=243, Percent_Identity=51.0288065843621, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24655794, Length=243, Percent_Identity=51.0288065843621, Blast_Score=248, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25761; Mature: 25761

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKVKKDAVEALAGLLFDGMTIMAGGFGLCGIPENLIAAIREAGTKDLTVISNNCGVDG
CCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCC
FGLGILLENRQIKKMVSSYVGENKLFEQLYLSGELELEFNPQGTLAERIRAGGAGIPAFF
EEEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHHH
TRTGYGTLVAEGKETREFDGEMYVMERGLTADLSIVKAWKADAEGNLIYRKTARNFNPMM
HCCCCEEEEECCCHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHH
ATAGKKTVVEVEELVAIGELDKDAIHTPGIYVDRLIKGAKFEKRIERVTTRQKETA
HCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDKVKKDAVEALAGLLFDGMTIMAGGFGLCGIPENLIAAIREAGTKDLTVISNNCGVDG
CCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCC
FGLGILLENRQIKKMVSSYVGENKLFEQLYLSGELELEFNPQGTLAERIRAGGAGIPAFF
EEEEEEECCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCHHH
TRTGYGTLVAEGKETREFDGEMYVMERGLTADLSIVKAWKADAEGNLIYRKTARNFNPMM
HCCCCEEEEECCCHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCHH
ATAGKKTVVEVEELVAIGELDKDAIHTPGIYVDRLIKGAKFEKRIERVTTRQKETA
HCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]