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The map label for this gene is visC [H]

Identifier: 16124362

GI number: 16124362

Start: 116870

End: 118099

Strand: Direct

Name: visC [H]

Synonym: CC_0107

Alternate gene names: 16124362

Gene position: 116870-118099 (Clockwise)

Preceding gene: 16124361

Following gene: 16124367

Centisome position: 2.91

GC content: 71.63

Gene sequence:

>1230_bases
GTGATCATCGCCGGCGCCGGCATGGCCGGCTCCACCCTGGCCCTGGCTCTGGCCTCGGGCGGCCTGAGGCCGCTGCTGGT
CGATCCTGCGCCCTTCGAGGCCCAGCTGGCCCCGACCTTCGATGGTCGCAGCTCGGCGATCGCCTATTCCTCGTTCCGTC
AGTGGCGGGCGATCGGCGCGGGCCAGGCGCTGGAGCCGCACGCCCAGCGCATCGAGCAGATCCTGGTCACCGACGGCCGC
ACGCCCGGCGCGGCGGCCCGCAAGCCGCTGCCGGCCTTCCTGCGCTTCGACTCCAGTGAGATCTCCGGGCGCATCGAGGG
CGAGCCGCTGGGCTATCTGGTCGAGAACCGCCAGATCCGCGCCGCGCTCTCCAAGGCCGTCATCGACAAGAACATCCCGG
TGATTGCGCCGATGGCCGCCAAGGCCTTGTCGGTCGAGCCCGGCGCGGCAAAGCTGACCCTGTCGGACGGCCGAGTGCTG
ACCGCGCCTCTGGCCGTCAGCGCCGAGGGGCGGGGCTCGGTGCTACGCCGCGCAGCCGGTATCGGCGACATCGGCTGGAG
CTATGGCCAGAGCGGCGTGGTCTGCACCGTCAGGCTGGAGCGCCCGCACGAGGGCGTGGCCCACGAATACTTCCTGCCCA
GCGGCCCCTTCGCCATCCTGCCGCTGACCGACAATCGCGCGAGCCTCGTGTGGACCGAGAGCACCGCGCGCGGCGAGGCC
TTGCGCCAGGCGGGCCCCGAGGCCTTCCACGCCCACCTGATGCGCCGGTTCGGCGACTTCCTGGGCGCGGTGTCGATCGA
GGGGCCGATCTTCGTCTATCCGCTGTCGCTGTCCCTGGCCGAGCGCATGGTCGCCCCGCGTCTGGCCTTGATTGGTGACG
CCGCTCACGGCGTGCACCCGATCGCGGGTCAGGGCCTGAATCTGGGCCTCAAGGACGCCGCCGCCCTGGCCGAAGTGCTG
GTCGAGGCGGTGCGCCACGGCGAAGACATCGGGGCCGAGGCCGTGCTGGAGCGTTACGCCCGCTGGCGGCGGTTCGACAC
CGTGACCAACGCCCTGGCCTTCGACGCCTTTGTGCGGATCTTCTCCAACGACAACCCGCTGCTGCGGCTGGCGCGGGGCG
CGGGTCTGGCGGTGGTCAACCAGATCGCCCCGGCGCGCCGCTTCTTCATGCACGAGGCCGGCGGCGGGGTGGGTGATCTG
CCGAAGCTTTTGCGGGGGCAAGCGCTGTAA

Upstream 100 bases:

>100_bases
CCGAGAGCCATAAGTAGGGACCCGGCTCTGGACAGCGACCGGCGGCGAGGCCCATATCGCCGCCATGCGCGCCCCCAACG
CCCCTTCGCACGACGCTGAT

Downstream 100 bases:

>100_bases
GGGCGCTTTCTTTCCTCCCCCTTTGGGGGAGGGGGACCGGCGAACGCCGGTGGAGGGGCCCTGTGTGGTGGTGATCTCAC
CACCGCTTCGCGGACCCCCT

Product: 2-octaprenyl-6-methoxyphenol hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MIIAGAGMAGSTLALALASGGLRPLLVDPAPFEAQLAPTFDGRSSAIAYSSFRQWRAIGAGQALEPHAQRIEQILVTDGR
TPGAAARKPLPAFLRFDSSEISGRIEGEPLGYLVENRQIRAALSKAVIDKNIPVIAPMAAKALSVEPGAAKLTLSDGRVL
TAPLAVSAEGRGSVLRRAAGIGDIGWSYGQSGVVCTVRLERPHEGVAHEYFLPSGPFAILPLTDNRASLVWTESTARGEA
LRQAGPEAFHAHLMRRFGDFLGAVSIEGPIFVYPLSLSLAERMVAPRLALIGDAAHGVHPIAGQGLNLGLKDAAALAEVL
VEAVRHGEDIGAEAVLERYARWRRFDTVTNALAFDAFVRIFSNDNPLLRLARGAGLAVVNQIAPARRFFMHEAGGGVGDL
PKLLRGQAL

Sequences:

>Translated_409_residues
MIIAGAGMAGSTLALALASGGLRPLLVDPAPFEAQLAPTFDGRSSAIAYSSFRQWRAIGAGQALEPHAQRIEQILVTDGR
TPGAAARKPLPAFLRFDSSEISGRIEGEPLGYLVENRQIRAALSKAVIDKNIPVIAPMAAKALSVEPGAAKLTLSDGRVL
TAPLAVSAEGRGSVLRRAAGIGDIGWSYGQSGVVCTVRLERPHEGVAHEYFLPSGPFAILPLTDNRASLVWTESTARGEA
LRQAGPEAFHAHLMRRFGDFLGAVSIEGPIFVYPLSLSLAERMVAPRLALIGDAAHGVHPIAGQGLNLGLKDAAALAEVL
VEAVRHGEDIGAEAVLERYARWRRFDTVTNALAFDAFVRIFSNDNPLLRLARGAGLAVVNQIAPARRFFMHEAGGGVGDL
PKLLRGQAL
>Mature_409_residues
MIIAGAGMAGSTLALALASGGLRPLLVDPAPFEAQLAPTFDGRSSAIAYSSFRQWRAIGAGQALEPHAQRIEQILVTDGR
TPGAAARKPLPAFLRFDSSEISGRIEGEPLGYLVENRQIRAALSKAVIDKNIPVIAPMAAKALSVEPGAAKLTLSDGRVL
TAPLAVSAEGRGSVLRRAAGIGDIGWSYGQSGVVCTVRLERPHEGVAHEYFLPSGPFAILPLTDNRASLVWTESTARGEA
LRQAGPEAFHAHLMRRFGDFLGAVSIEGPIFVYPLSLSLAERMVAPRLALIGDAAHGVHPIAGQGLNLGLKDAAALAEVL
VEAVRHGEDIGAEAVLERYARWRRFDTVTNALAFDAFVRIFSNDNPLLRLARGAGLAVVNQIAPARRFFMHEAGGGVGDL
PKLLRGQAL

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967307, Length=348, Percent_Identity=33.6206896551724, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI32967305, Length=348, Percent_Identity=33.6206896551724, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1789273, Length=409, Percent_Identity=33.7408312958435, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1789274, Length=400, Percent_Identity=33.5, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1786883, Length=383, Percent_Identity=36.2924281984334, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25146631, Length=442, Percent_Identity=27.1493212669683, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321694, Length=463, Percent_Identity=26.133909287257, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920760, Length=433, Percent_Identity=26.7898383371824, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43252; Mature: 43252

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIAGAGMAGSTLALALASGGLRPLLVDPAPFEAQLAPTFDGRSSAIAYSSFRQWRAIGA
CEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCC
GQALEPHAQRIEQILVTDGRTPGAAARKPLPAFLRFDSSEISGRIEGEPLGYLVENRQIR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEECCHHCCCEECCCCCEEEECCCHHH
AALSKAVIDKNIPVIAPMAAKALSVEPGAAKLTLSDGRVLTAPLAVSAEGRGSVLRRAAG
HHHHHHHHHCCCCEEECCHHHHEECCCCCEEEEECCCEEEEECEEEECCCCHHHHHHHCC
IGDIGWSYGQSGVVCTVRLERPHEGVAHEYFLPSGPFAILPLTDNRASLVWTESTARGEA
CCCCCHHCCCCCEEEEEEECCCCCCCCCEEECCCCCEEEEEECCCCEEEEEECCCHHHHH
LRQAGPEAFHAHLMRRFGDFLGAVSIEGPIFVYPLSLSLAERMVAPRLALIGDAAHGVHP
HHHCCHHHHHHHHHHHHHHHHCCEEECCCEEEEECCHHHHHHHHHCHHHEECCCCCCCCC
IAGQGLNLGLKDAAALAEVLVEAVRHGEDIGAEAVLERYARWRRFDTVTNALAFDAFVRI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSNDNPLLRLARGAGLAVVNQIAPARRFFMHEAGGGVGDLPKLLRGQAL
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MIIAGAGMAGSTLALALASGGLRPLLVDPAPFEAQLAPTFDGRSSAIAYSSFRQWRAIGA
CEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCHHHHHHHHHHHHHCC
GQALEPHAQRIEQILVTDGRTPGAAARKPLPAFLRFDSSEISGRIEGEPLGYLVENRQIR
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEECCHHCCCEECCCCCEEEECCCHHH
AALSKAVIDKNIPVIAPMAAKALSVEPGAAKLTLSDGRVLTAPLAVSAEGRGSVLRRAAG
HHHHHHHHHCCCCEEECCHHHHEECCCCCEEEEECCCEEEEECEEEECCCCHHHHHHHCC
IGDIGWSYGQSGVVCTVRLERPHEGVAHEYFLPSGPFAILPLTDNRASLVWTESTARGEA
CCCCCHHCCCCCEEEEEEECCCCCCCCCEEECCCCCEEEEEECCCCEEEEEECCCHHHHH
LRQAGPEAFHAHLMRRFGDFLGAVSIEGPIFVYPLSLSLAERMVAPRLALIGDAAHGVHP
HHHCCHHHHHHHHHHHHHHHHCCEEECCCEEEEECCHHHHHHHHHCHHHEECCCCCCCCC
IAGQGLNLGLKDAAALAEVLVEAVRHGEDIGAEAVLERYARWRRFDTVTNALAFDAFVRI
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSNDNPLLRLARGAGLAVVNQIAPARRFFMHEAGGGVGDLPKLLRGQAL
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]